Cas no 885681-96-9 (4-Bromo-2-iodobenzyl bromide)

4-Bromo-2-iodobenzyl bromide is a halogenated aromatic compound commonly used as a versatile intermediate in organic synthesis and pharmaceutical research. Its key advantages include the presence of multiple reactive sites (bromine and iodine substituents), enabling selective functionalization for cross-coupling reactions, nucleophilic substitutions, or further derivatization. The benzyl bromide moiety enhances reactivity in alkylation or polymerization processes. This compound is particularly valuable in constructing complex molecular architectures due to its stability and compatibility with various reaction conditions. It serves as a critical building block in medicinal chemistry for developing bioactive molecules and advanced materials. High purity grades ensure consistent performance in demanding synthetic applications.
4-Bromo-2-iodobenzyl bromide structure
4-Bromo-2-iodobenzyl bromide structure
Product Name:4-Bromo-2-iodobenzyl bromide
CAS No:885681-96-9
MF:C7H5Br2I
MW:375.82707285881
MDL:MFCD18391672
CID:1015916
PubChem ID:53231307
Update Time:2025-11-07

4-Bromo-2-iodobenzyl bromide Chemical and Physical Properties

Names and Identifiers

    • 4-BROMO-1-(BROMOMETHYL)-2-IODOBENZENE
    • 4-BROMO-2-IODOBENZYL BROMIDE
    • Benzene, 4-bromo-1-(bromomethyl)-2-iodo-
    • 2-Iodo-4-bromobenzyl bromide
    • IHHHQROJDZQCQH-UHFFFAOYSA-N
    • 2-Iodo-4-bromo(bromomethyl)benzene
    • BCP30403
    • OR40663
    • FCH1369998
    • AK677333
    • AM804742
    • 4-Bromo-1-(bromomethyl)-2-iodobenzene pound>>2-Iodo-4-bromobenzyl bromide
    • 4-Bromo-1-(bromomethyl)-2-iodobenzene (ACI)
    • 4-Bromo-1-bromomethyl-2-iodobenzene
    • MFCD18391672
    • 885681-96-9
    • EN300-6481279
    • DS-20040
    • SY346799
    • AKOS030627618
    • DTXSID601286061
    • YSZC343
    • DB-316242
    • CS-0040964
    • SCHEMBL28419
    • 4-Bromo-2-iodobenzyl bromide
    • MDL: MFCD18391672
    • Inchi: 1S/C7H5Br2I/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2
    • InChI Key: IHHHQROJDZQCQH-UHFFFAOYSA-N
    • SMILES: BrC1C=C(I)C(CBr)=CC=1

Computed Properties

  • Exact Mass: 375.77822g/mol
  • Monoisotopic Mass: 373.78027g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 108
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 0
  • XLogP3: 3.8

4-Bromo-2-iodobenzyl bromide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A013032667-250mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
250mg
$484.80 2023-08-31
Alichem
A013032667-500mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
500mg
$839.45 2023-08-31
Alichem
A013032667-1g
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
1g
$1564.50 2023-08-31
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-VS648-250mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
250mg
507CNY 2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-VS648-1g
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
1g
900.0CNY 2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-VS648-5g
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
5g
2613.0CNY 2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-VS648-100mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
100mg
242CNY 2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-VS648-50mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
50mg
133.0CNY 2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-VS648-200mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
200mg
300.0CNY 2021-07-12
Apollo Scientific
OR40663-250mg
4-Bromo-2-iodobenzyl bromide
885681-96-9 97%
250mg
£28.00 2025-02-20

4-Bromo-2-iodobenzyl bromide Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Carbon tetrabromide ,  Triphenylphosphine Solvents: Dichloromethane ;  0 °C; 0 °C → rt
Reference
Access to chiral tetrahydrofluorenes through a palladium-catalyzed enantioselective tandem intramolecular Heck/Tsuji-Trost reaction
Zhang, Ying; Shen, Hong-Cheng; Li, Yang-Yang; Huang, Yong-Shuang; Han, Zhi-Yong; et al, Chemical Communications (Cambridge, 2019, 55(26), 3769-3772

Production Method 2

Reaction Conditions
1.1 Solvents: 1,2-Dichloroethane ;  rt
1.2 Reagents: N-Bromosuccinimide Catalysts: Benzoyl peroxide ;  rt → reflux; 5 h, reflux; reflux → rt
Reference
Functionalized Dibenzoborepins as Components of Small Molecule and Polymeric π-Conjugated Electronic Materials
Caruso, Anthony; Tovar, John D., Journal of Organic Chemistry, 2011, 76(7), 2227-2239

Production Method 3

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Catalysts: Benzoyl peroxide Solvents: Carbon tetrachloride ;  12 h, reflux
Reference
Dihydrobiphenylenes through Ruthenium-Catalyzed [2+2+2] Cycloadditions of ortho-Alkenylarylacetylenes with Alkynes
Garcia-Rubin, Silvia; Gonzalez-Rodriguez, Carlos; Garcia-Yebra, Cristina; Varela, Jesus A.; Esteruelas, Miguel A.; et al, Angewandte Chemie, 2014, 53(7), 1841-1844

Production Method 4

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Catalysts: Benzoyl peroxide Solvents: Acetonitrile ;  80 °C
Reference
tBuOK-Promoted Cyclization of Imines with Aryl Halides
Li, Ya-Wei; Zheng, Hong-Xing; Yang, Bo; Shan, Xiang-Huan; Qu, Jian-Ping ; et al, Organic Letters, 2020, 22(11), 4553-4556

Production Method 5

Reaction Conditions
1.1 Reagents: Carbon tetrabromide Solvents: Dichloromethane
Reference
CuSO4-Catalyzed dual annulation to synthesize O, S or N-containing tetracyclic heteroacenes
Shan, Xiang-Huan; Yang, Bo; Qu, Jian-Ping; Kang, Yan-Biao, Chemical Communications (Cambridge, 2020, 56(29), 4063-4066

Production Method 6

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Catalysts: Benzoyl peroxide Solvents: Benzene ;  4 h, reflux
Reference
CuSO4-Catalyzed Tandem C(sp3)-H Insertion Cyclization of Toluenes with Isonitriles to Form Indoles
Shan, Xiang-Huan; Wang, Mei-Mei; Tie, Lin; Qu, Jian-Ping ; Kang, Yan-Biao, Organic Letters, 2020, 22(2), 357-360

Production Method 7

Reaction Conditions
1.1 Reagents: Carbon tetrabromide ,  Triphenylphosphine Solvents: Dichloromethane ;  rt; 4 h, rt
Reference
Copper-catalyzed oxidative benzylic C-H cyclization via iminyl radical from intermolecular anion-radical redox relay
Shan, Xiang-Huan; Zheng, Hong-Xing; Yang, Bo; Tie, Lin; Fu, Jia-Le; et al, Nature Communications, 2019, 10(1), 1-9

4-Bromo-2-iodobenzyl bromide Raw materials

4-Bromo-2-iodobenzyl bromide Preparation Products

4-Bromo-2-iodobenzyl bromide Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:885681-96-9)4-Bromo-1-(bromomethyl)-2-iodobenzene, alpha,4-Dibromo-2-iodotoluene
Order Number:sfd7437
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:885681-96-9)4-Bromo-2-iodobenzyl bromide
Order Number:A1060499
Stock Status:in Stock
Quantity:5g/25g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 17:54
Price ($):330.0/1063.0

Additional information on 4-Bromo-2-iodobenzyl bromide

Market Research and Analysis Report on 4-Bromo-2-Iodobenzyl Bromide (CAS No. 885681-96-9)

The compound 4-Bromo-2-Iodobenzyl Bromide, identified by the CAS number 885681-96-9, has emerged as a significant reagent in the fields of organic synthesis, drug discovery, and chemical biology. This compound is widely utilized due to its unique chemical properties, making it an essential building block in the development of complex molecules with potential therapeutic applications.

Recent studies have highlighted the increasing demand for 4-Bromo-2-Iodobenzyl Bromide in the pharmaceutical industry, particularly in the synthesis of bioactive compounds and intermediates. Its role in Suzuki-Miyaura coupling reactions and other cross-coupling processes has further solidified its position as a critical reagent in modern organic chemistry.

Market analysis indicates a growing trend in the procurement of this compound across various regions, driven by advancements in drug discovery pipelines and the rising emphasis on precision medicine. Key players in the global market are focusing on optimizing supply chains to meet the escalating demand while ensuring compliance with regulatory standards.

The application of 4-Bromo-2-Iodobenzyl Bromide extends beyond pharmaceuticals into agrochemicals and materials science, underscoring its versatility. Researchers are actively exploring its potential in developing novel materials with tailored properties, further broadening its market scope.

In conclusion, 4-Bromo-2-Iodobenzyl Bromide (CAS No. 885681-96-9) stands as a pivotal compound in contemporary chemical research and industrial applications. Its continued relevance is expected to drive sustained growth in its market presence, making it a critical focus area for stakeholders in the chemical and pharmaceutical sectors.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:885681-96-9)4-Bromo-1-(bromomethyl)-2-iodobenzene, alpha,4-Dibromo-2-iodotoluene
sfd7437
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Amadis Chemical Company Limited
(CAS:885681-96-9)4-Bromo-2-iodobenzyl bromide
A1060499
Purity:99%/99%
Quantity:5g/25g
Price ($):330.0/1063.0
Email