• 1. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 2. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
  Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
• 3. Emerging investigator series: heterogeneous reactions of sulfur dioxide on mineral dust nanoparticles: from single component to mixed components?
  Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
• 4. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridine carboxaldehydes

Comprehensive Overview of 2-Ethoxynicotinaldehyde (CAS No. 885278-07-9): Properties, Applications, and Industry Insights

2-Ethoxynicotinaldehyde (CAS No. 885278-07-9) is a specialized organic compound belonging to the nicotinaldehyde family. This compound has garnered significant attention in recent years due to its versatile applications in pharmaceuticals, agrochemicals, and material science. With the increasing demand for high-purity aldehydes and nicotine derivatives, 2-Ethoxynicotinaldehyde has emerged as a key intermediate in synthetic chemistry. Its unique molecular structure, featuring an ethoxy group at the 2-position of the pyridine ring, enhances its reactivity and selectivity in various chemical transformations.

The compound's CAS number 885278-07-9 is a critical identifier for researchers and manufacturers seeking reliable sourcing and regulatory compliance. Recent trends in green chemistry and sustainable synthesis have further elevated the importance of 2-Ethoxynicotinaldehyde, as it can be utilized in eco-friendly catalytic processes. Industry reports highlight its role in the development of novel APIs (Active Pharmaceutical Ingredients) and biodegradable materials, aligning with global sustainability goals.

One of the most searched questions related to 2-Ethoxynicotinaldehyde is: "What are the synthetic routes for 2-Ethoxynicotinaldehyde?" The compound is typically synthesized via Vilsmeier-Haack formylation or oxidation of 2-ethoxynicotinyl alcohol, with recent advancements focusing on microwave-assisted synthesis to improve yield and reduce reaction time. Researchers are also exploring its potential in photocatalysis and metal-organic frameworks (MOFs), addressing the growing interest in energy-efficient chemical processes.

In the pharmaceutical sector, 2-Ethoxynicotinaldehyde serves as a precursor for antiviral agents and CNS-targeting drugs, reflecting the industry's focus on neurological therapeutics. Its compatibility with cross-coupling reactions (e.g., Suzuki-Miyaura) makes it invaluable for constructing complex heterocycles. Meanwhile, agrochemical applications leverage its role in developing crop protection agents with reduced environmental impact.

From a commercial perspective, the global market for 2-Ethoxynicotinaldehyde is projected to grow at a CAGR of 6.2% (2023-2030), driven by R&D investments in precision medicine and smart materials. Analytical techniques like HPLC and GC-MS are essential for quality control, ensuring compliance with ICH guidelines. Storage recommendations emphasize protection from light and moisture, with inert atmospheres preferred for long-term stability.

Emerging discussions in scientific forums often revolve around scalability challenges and cost-effective purification methods for CAS 885278-07-9. Innovations such as continuous flow chemistry and enzymatic catalysis are being explored to address these gaps. Additionally, the compound's spectral data (IR, NMR) is frequently requested for academic validation, underscoring its relevance in structure-activity relationship (SAR) studies.

In conclusion, 2-Ethoxynicotinaldehyde (CAS No. 885278-07-9) represents a dynamic intersection of chemistry and innovation. Its multifaceted applications—from drug discovery to advanced materials—position it as a compound of enduring scientific and industrial significance. As research continues to uncover new functionalities, this molecule will likely remain at the forefront of specialty chemical development.

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• 35969-54-1(2-ethoxypyridine-3-carboxylic acid)
• 58819-72-0(2,6-dimethoxypyridine-3-carbaldehyde)
• 885278-10-4(2-Isopropoxynicotinaldehyde)
• 1203499-47-1(2-methoxy-5-methylpyridine-3-carbaldehyde)
• 97455-61-3(6-ethoxypyridine-3-carbaldehyde)
• 123506-67-2(6-methoxy-5-methylpyridine-3-carbaldehyde)
• 885278-12-6(2-propoxypyridine-3-carbaldehyde)
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• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)