Cas no 885273-17-6 (2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine)

2-(3-Methoxyphenyl)-1,3-oxazol-4-ylmethanamine is a heterocyclic amine derivative featuring an oxazole core substituted with a 3-methoxyphenyl group. This compound is of interest in medicinal chemistry and pharmaceutical research due to its structural versatility, which allows for potential applications as a building block in the synthesis of bioactive molecules. The presence of the methoxy and oxazole moieties enhances its utility in drug discovery, particularly in the development of CNS-targeting agents or enzyme modulators. Its well-defined chemical structure ensures reproducibility in synthetic applications, while its moderate reactivity facilitates further functionalization. The compound is typically handled under controlled conditions due to its amine functionality.
2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine structure
885273-17-6 structure
Product Name:2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine
CAS No:885273-17-6
MF:C11H12N2O2
MW:204.225182533264
MDL:MFCD06738607
CID:710983
PubChem ID:65289007
Update Time:2025-06-11

2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine Chemical and Physical Properties

Names and Identifiers

    • 4-Oxazolemethanamine,2-(3-methoxyphenyl)-
    • 2-(3-methoxyphenyl)-N-methyl-1,3-oxazol-4-amine
    • 2-(3-Methoxy-phenyl)-oxazol-4-yl-methylamine
    • 2-(3-METHOXYPHENYL)OXAZOL-4-YL-METHYLAMINE,
    • (2-(3-Methoxyphenyl)oxazol-4-yl)methanamine
    • 2-(2-AMINO-1,3-THIAZOL-5-YL)-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL
    • 2-(3-Methoxyphenyl)-oxazol-4-yl-methylamine
    • 4-Oxazolemethanamine,2-(3-methoxyphenyl)
    • C-[2-(3-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE
    • 2-(3-Methoxyphenyl)-4-oxazolemethanamine (ACI)
    • AKOS014623770
    • 885273-17-6
    • CS-0342202
    • 1-[2-(3-METHOXYPHENYL)-1,3-OXAZOL-4-YL]METHANAMINE
    • MFCD06738607
    • [2-(3-METHOXYPHENYL)-1,3-OXAZOL-4-YL]METHANAMINE
    • 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine
    • MDL: MFCD06738607
    • Inchi: 1S/C11H12N2O2/c1-14-10-4-2-3-8(5-10)11-13-9(6-12)7-15-11/h2-5,7H,6,12H2,1H3
    • InChI Key: VTOCLFFVCLIXPZ-UHFFFAOYSA-N
    • SMILES: N1C(CN)=COC=1C1C=C(OC)C=CC=1

Computed Properties

  • Exact Mass: 204.09000
  • Monoisotopic Mass: 204.089877630g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 201
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.3
  • Topological Polar Surface Area: 61.3?2

Experimental Properties

  • Boiling Point: 373.0±52.0°C at 760 mmHg
  • PSA: 61.28000
  • LogP: 2.50920

2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine Security Information

2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine Customs Data

  • HS CODE:2934999090
  • Customs Data:

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine Pricemore >>

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Additional information on 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine

Professional Introduction to Compound with CAS No. 885273-17-6 and Product Name: 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine

The compound identified by the CAS number 885273-17-6 and the product name 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine represents a significant area of interest in the field of chemical and biomedical research. This compound belongs to a class of heterocyclic amines that have garnered considerable attention due to their diverse pharmacological properties and potential applications in drug discovery. The structural framework of this molecule, featuring a 3-methoxyphenyl group and an oxazol ring system, contributes to its unique chemical and biological characteristics, making it a valuable candidate for further investigation.

In recent years, there has been a growing emphasis on the development of novel therapeutic agents that target specific biological pathways. The 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine structure has shown promise in preliminary studies as a modulator of various enzymatic and receptor interactions. Its ability to interact with biological targets at the molecular level has positioned it as a potential lead compound for the development of new medications. The presence of the 3-methoxyphenyl moiety is particularly noteworthy, as it is known to influence the electronic properties and binding affinity of the molecule, thereby enhancing its pharmacological efficacy.

One of the most compelling aspects of this compound is its potential role in addressing neurological disorders. The oxazol ring system is commonly found in bioactive molecules that exhibit neuroprotective and anti-inflammatory properties. Studies have indicated that compounds with similar structural motifs can interact with neurotransmitter systems, potentially offering therapeutic benefits in conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders. The 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine molecule, with its unique combination of functional groups, may serve as a foundation for designing next-generation neuropharmacological agents.

Furthermore, the 3-methoxyphenyl group in this compound adds an additional layer of complexity that could be exploited for therapeutic purposes. This substituent is known to enhance lipophilicity and metabolic stability, which are critical factors in drug design. By optimizing the placement and electronic properties of this group, researchers can fine-tune the pharmacokinetic profile of the molecule, improving its bioavailability and reducing potential side effects. This aspect makes 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine an attractive candidate for further development in medicinal chemistry.

Recent advancements in computational chemistry have also contributed to a deeper understanding of the interactions between this compound and biological targets. Molecular docking studies have revealed that 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine can bind effectively to several key enzymes and receptors involved in disease pathways. These findings provide a strong rationale for conducting further experimental investigations to validate these computational predictions. The integration of computational methods with traditional wet-lab approaches has accelerated the drug discovery process significantly.

The synthesis of 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine presents an interesting challenge due to its complex structural features. However, modern synthetic methodologies have made it increasingly feasible to construct such molecules with high precision. Techniques such as transition-metal-catalyzed cross-coupling reactions and palladium-mediated transformations have been instrumental in achieving efficient synthetic routes. These advancements not only facilitate the production of this compound but also enable the facile introduction of structural variations for optimization purposes.

In conclusion, the compound identified by CAS number 885273-17-6 and named 2-(3-methoxyphenyl)-1,3-oxazol-4-ylmethanamine represents a promising candidate for further exploration in pharmaceutical research. Its unique structural features and demonstrated interactions with biological targets make it a valuable asset in the quest for novel therapeutic agents. As research continues to uncover new applications for this molecule, it is likely that it will play an increasingly important role in addressing some of today's most pressing medical challenges.

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