Cas no 88491-61-6 (3-Bromopyridazine)

3-Bromopyridazine (CAS 1455-52-1) is a heterocyclic organic compound featuring a pyridazine ring substituted with a bromine atom at the 3-position. This compound serves as a versatile intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. Its bromine moiety enables efficient cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, facilitating the construction of complex pyridazine derivatives. The electron-deficient nature of the pyridazine ring enhances reactivity in nucleophilic substitution reactions. 3-Bromopyridazine is valued for its stability under standard conditions and its compatibility with a range of reaction conditions, making it a reliable building block for researchers in medicinal chemistry and material science.
3-Bromopyridazine structure
3-Bromopyridazine structure
Product Name:3-Bromopyridazine
CAS No:88491-61-6
MF:C4H3BrN2
MW:158.984019517899
MDL:MFCD10688587
CID:709501
PubChem ID:13126699
Update Time:2025-05-27

3-Bromopyridazine Chemical and Physical Properties

Names and Identifiers

    • Pyridazine, 3-bromo-
    • 3-Bromopyridazine
    • 3-bromo-Pyridazine
    • Pyridazine, 3-bromo- (9CI)
    • ILYSUJOMLYXAOC-UHFFFAOYSA-N
    • BCP27608
    • STL556866
    • BBL103057
    • VP30013
    • MB08580
    • SY007900
    • AM804482
    • ST2405001
    • AB0028175
    • X0220
    • 491B616
    • J-
    • 3-Bromopyridazine (ACI)
    • AC-25814
    • MFCD10688587
    • 88491-61-6
    • EN300-42334
    • CS-W004020
    • SCHEMBL180986
    • AKOS009548430
    • DTXSID10520082
    • GS-4388
    • J-512136
    • MDL： MFCD10688587
    • Inchi： 1S/C4H3BrN2/c5-4-2-1-3-6-7-4/h1-3H
    • InChI Key： ILYSUJOMLYXAOC-UHFFFAOYSA-N
    • SMILES： BrC1C=CC=NN=1

Computed Properties

  • Exact Mass: 157.94800
  • Monoisotopic Mass: 157.94796g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 0
  • Complexity: 57.7
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.2
  • Topological Polar Surface Area: 25.8

Experimental Properties

  • Density: 1.727
  • Melting Point: 73-74 °C
  • Boiling Point: 270℃ at 760 mmHg
  • Flash Point: 117.075℃
  • Refractive Index: 1.568
  • PSA: 25.78000
  • LogP: 1.23910

3-Bromopyridazine Security Information

3-Bromopyridazine Customs Data

  • HS CODE：2933990090
  • Customs Data：

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-Bromopyridazine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Matrix Scientific
074611-1g
3-Bromopyridazine, 95+%
 88491-61-6 95+%
1g
 $98.00 2023-09-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-LA560-250mg
3-Bromopyridazine
 88491-61-6 97%
250mg
 221CNY 2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-LA560-50mg
3-Bromopyridazine
 88491-61-6 97%
50mg
 55.0CNY 2021-08-04
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-LA560-5g
3-Bromopyridazine
 88491-61-6 97%
5g
 1051.0CNY 2021-08-04
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-LA560-1g
3-Bromopyridazine
 88491-61-6 97%
1g
 316.0CNY 2021-08-04
Matrix Scientific
074611-5g
3-Bromopyridazine, 95+%
 88491-61-6 95+%
5g
 $296.00 2023-09-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-LA560-200mg
3-Bromopyridazine
 88491-61-6 97%
200mg
 109.0CNY 2021-08-04
TRC
B695863-100mg
3-Bromopyridazine
 88491-61-6
100mg
 $ 64.00 2023-04-18
TRC
B695863-250mg
3-Bromopyridazine
 88491-61-6
250mg
 $ 75.00 2023-04-18
TRC
B695863-500mg
3-Bromopyridazine
 88491-61-6
500mg
 $ 87.00 2023-04-18

3-Bromopyridazine Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Sodium hydroxide Solvents: Water
Reference
Pyridazines by addition of diazoalkanes to 1-bromo- and 1,2-dibromocyclopropenes
Dulayymi, Ahmad R.; et al, Tetrahedron, 1998, 54(42), 12897-12906

Production Method 2

Reaction Conditions
1.1 Solvents: Diethyl ether
1.2 Solvents: Water
2.1 Solvents: Chloroform
3.1 Reagents: Sodium hydroxide Solvents: Water
Reference
Pyridazines by addition of diazoalkanes to 1-bromo- and 1,2-dibromocyclopropenes
Dulayymi, Ahmad R.; et al, Tetrahedron, 1998, 54(42), 12897-12906

Production Method 3

Reaction Conditions
1.1 Reagents: Phosphoric tribromide Solvents: Acetonitrile ;  25 min, 80 °C
1.2 Reagents: Sodium carbonate Solvents: Water ;  basified
Reference
Synthesis of 3-bromopyridazine
Hong, Dong-feng; et al, Yingyong Huagong, 2012, 41(9), 1645-1647

Production Method 4

Reaction Conditions
Reference
Product class 8: pyridazines
Haider, N.; et al, Science of Synthesis, 2004, 16, 125-249

Production Method 5

Reaction Conditions
1.1 Solvents: Chloroform
2.1 Reagents: Sodium hydroxide Solvents: Water
Reference
Pyridazines by addition of diazoalkanes to 1-bromo- and 1,2-dibromocyclopropenes
Dulayymi, Ahmad R.; et al, Tetrahedron, 1998, 54(42), 12897-12906

Production Method 6

Reaction Conditions
1.1 Reagents: Sodium hydroxide ,  Hydrogen Catalysts: Palladium Solvents: Ethanol ;  6 h, 1.5 - 2 MPa, rt → 80 °C
2.1 Reagents: Phosphoric tribromide Solvents: Acetonitrile ;  25 min, 80 °C
2.2 Reagents: Sodium carbonate Solvents: Water ;  basified
Reference
Synthesis of 3-bromopyridazine
Hong, Dong-feng; et al, Yingyong Huagong, 2012, 41(9), 1645-1647

Production Method 7

Reaction Conditions
1.1 Reagents: Sodium hydroxide Solvents: Water ;  90 °C; 6 h, 90 °C → 100 °C; 100 °C → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 3
2.1 Reagents: Sodium hydroxide ,  Hydrogen Catalysts: Palladium Solvents: Ethanol ;  6 h, 1.5 - 2 MPa, rt → 80 °C
3.1 Reagents: Phosphoric tribromide Solvents: Acetonitrile ;  25 min, 80 °C
3.2 Reagents: Sodium carbonate Solvents: Water ;  basified
Reference
Synthesis of 3-bromopyridazine
Hong, Dong-feng; et al, Yingyong Huagong, 2012, 41(9), 1645-1647

3-Bromopyridazine Raw materials

3-Bromopyridazine Preparation Products

3-Bromopyridazine Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:88491-61-6)Pyridazine, 3-bromo- (9CI)
Order Number:sfd2155
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
Price ($):discuss personally

3-Bromopyridazine Related Literature

Related Categories

88491-61-6 (3-Bromopyridazine) Related Products

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:88491-61-6)Pyridazine, 3-bromo- (9CI)
sfd2155
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email