Cas no 88127-22-4 (Guanosine, 2'-deoxy-N,N-dimethyl-)

Guanosine, 2'-deoxy-N,N-dimethyl- structure
88127-22-4 structure
Product Name:Guanosine, 2'-deoxy-N,N-dimethyl-
CAS No:88127-22-4
MF:C12H17N5O4
MW:295.294481992722
CID:644109
Update Time:2023-12-05

Guanosine, 2'-deoxy-N,N-dimethyl- Chemical and Physical Properties

Names and Identifiers

    • Guanosine, 2'-deoxy-N,N-dimethyl-
    • 2-(dimethylamino)-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
    • Inchi： 1S/C12H17N5O4/c1-16(2)12-14-10-9(11(20)15-12)13-5-17(10)8-3-6(19)7(4-18)21-8/h5-8,18-19H,3-4H2,1-2H3,(H,14,15,20)/t6-,7+,8+/m0/s1
    • InChI Key： IKDIHBAQIZQROC-XLPZGREQSA-N
    • SMILES： O=C1N=C(N(C)C)NC2N([C@H]3C[C@H](O)[C@@H](CO)O3)C=NC1=2

Guanosine, 2'-deoxy-N,N-dimethyl- Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Tributylstannane Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  1 h, reflux
2.1 Reagents: Ammonium hydroxide Solvents: Water ;  2 h, rt
Reference
Homopurine RP-stereo-defined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs
Maciaszek, Anna; et al, Organic & Biomolecular Chemistry, 2019, 17(18), 4611-4620

Production Method 2

Reaction Conditions
1.1 Reagents: Chlorotrimethylsilane ;  30 min, rt
1.2 1.5 h, rt
1.3 Solvents: Water ;  rt
2.1 Reagents: Tributylstannane Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  1 h, reflux
3.1 Reagents: Ammonium hydroxide Solvents: Water ;  2 h, rt
Reference
Homopurine RP-stereo-defined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs
Maciaszek, Anna; et al, Organic & Biomolecular Chemistry, 2019, 17(18), 4611-4620

Production Method 3

Reaction Conditions
1.1 Reagents: Ammonium hydroxide Solvents: Water ;  2 h, rt
Reference
Homopurine RP-stereo-defined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs
Maciaszek, Anna; et al, Organic & Biomolecular Chemistry, 2019, 17(18), 4611-4620

Production Method 4

Reaction Conditions
1.1 Reagents: Tributylstannane Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  1 h, reflux
2.1 Reagents: Chlorotrimethylsilane ;  30 min, rt
2.2 1.5 h, rt
2.3 Solvents: Water ;  rt
3.1 Reagents: Tributylstannane Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  1 h, reflux
4.1 Reagents: Ammonium hydroxide Solvents: Water ;  2 h, rt
Reference
Homopurine RP-stereo-defined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs
Maciaszek, Anna; et al, Organic & Biomolecular Chemistry, 2019, 17(18), 4611-4620

Production Method 5

Reaction Conditions
1.1 Reagents: Chlorotrimethylsilane ;  15 min, rt
1.2 30 min, rt
1.3 Solvents: Water ;  rt
2.1 Reagents: Tributylstannane Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  1 h, reflux
3.1 Reagents: Chlorotrimethylsilane ;  30 min, rt
3.2 1.5 h, rt
3.3 Solvents: Water ;  rt
4.1 Reagents: Tributylstannane Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  1 h, reflux
5.1 Reagents: Ammonium hydroxide Solvents: Water ;  2 h, rt
Reference
Homopurine RP-stereo-defined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs
Maciaszek, Anna; et al, Organic & Biomolecular Chemistry, 2019, 17(18), 4611-4620

Guanosine, 2'-deoxy-N,N-dimethyl- Raw materials

Guanosine, 2'-deoxy-N,N-dimethyl- Preparation Products

Guanosine, 2'-deoxy-N,N-dimethyl- Suppliers

NewCan Biotech Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:88127-22-4)2'-Deoxy-N2,N2-dimethylguanosine
Order Number:NC14163
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:01
Price ($):Price inquiry

Guanosine, 2'-deoxy-N,N-dimethyl- Related Literature

88127-22-4 (Guanosine, 2'-deoxy-N,N-dimethyl-) Related Products

Recommended suppliers
NewCan Biotech Limited
(CAS:88127-22-4)2'-Deoxy-N2,N2-dimethylguanosine
NC14163
Purity:97%
Quantity:10g
Price ($):Inquiry
Email