Production Method 1

1074-24-4

88111-74-4

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran ,  Hexane ;  10 min, -78 °C
1.2 -78 °C → rt; 1 h, rt

Reference

Preparation of Polyfunctional Aryl Azides from Aryl Triazenes. A New Synthesis of Ellipticine, 9-Methoxyellipticine, Isoellipticine, and 7-Carbethoxyisoellipticine

Liu, Ching-Yuan; et al, Journal of Organic Chemistry, 2007, 72(19), 7106-7115

Production Method 2

1074-24-4

88111-74-4

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran ,  Hexane ;  30 min, -78 °C
1.2 1.5 h, -30 °C; overnight, rt

Reference

H-Bonded Effects on Novel Supramolecular Dendrimers Containing Electron-Transporting Donor Dendrons and Single/Double H-Bonded Acceptor Emitters

Wu, Chung-Wen; et al, Macromolecules, 2006, 39(23), 7985-7997

Production Method 3

88111-73-3

88111-74-4

Reaction Conditions

1.1 Reagents: Sodium ethoxide Solvents: Ethanol ,  Nitropropane
1.2 -

Reference

Synthesis and chiral recognition of optically active crown ethers incorporating a helicene moiety as the chiral center

Yamamoto, Koji; et al, Journal of the Chemical Society, 1990, (2), 271-6

Production Method 4

1074-24-4

88111-74-4

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran ,  Hexane

Reference

Preparation of Polyfunctional Arylmagnesium, or Arylzinc Reagents Bearing a Triazene Moiety and Their Applications in Organic Synthesis

Liu, Ching-Yuan, 2007, , ,

Production Method 5

1074-24-4

2591-86-8

88111-74-4

Reaction Conditions

1.1 Solvents: Diethyl ether ,  Tetrahydrofuran ;  0 °C
1.2 Reagents: Butyllithium ;  1 h, 0 °C
1.3 3 - 6 h, rt
1.4 Reagents: Hydrochloric acid Solvents: Water ;  2 h, rt

Reference

Alkyne Metathesis with Simple Catalyst Systems: Efficient Synthesis of Conjugated Polymers Containing Vinyl Groups in Main or Side Chain

Brizius, Glen; et al, Journal of the American Chemical Society, 2000, 122(50), 12435-12440

Production Method 6

13862-28-7

78775-11-8

88111-74-4

Reaction Conditions

1.1 Reagents: Pyridinium, 1-fluoro-2,4,6-trimethyl-, tetrafluoroborate(1-) (1:1) Catalysts: 2-Aminobenzenesulfonic acid ,  Palladium diacetate Solvents: Trifluoroacetic acid ,  1,1,1,3,3,3-Hexafluoro-2-propanol ;  15 h, rt; 24 h, 90 °C

Reference

Pd-Catalyzed, ortho C-H Methylation and Fluorination of Benzaldehydes Using Orthanilic Acids as Transient Directing Groups

Chen, Xiao-Yang ; et al, Journal of the American Chemical Society, 2018, 140(8), 2789-2792

Production Method 7

88111-73-3

88111-74-4

Reaction Conditions

Reference

Synthesis and chiral recognition of novel crown ethers incorporating helicene chiral centers

Nakazaki, Masao; et al, Journal of the Chemical Society, 1983, (14), 787-8

Production Method 8

88111-74-4

Reaction Conditions

1.1 Reagents: Iodine ,  Bromine
2.1 Reagents: Butyllithium Solvents: Tetrahydrofuran

Reference

Remarkable Dependence of the Final Charge Separation Efficiency on the Donor-Acceptor Interaction in Photoinduced Electron Transfer

Higashino, Tomohiro; et al, Angewandte Chemie, 2016, 55(2), 629-633

Production Method 9

553-94-6

88111-74-4

Reaction Conditions

1.1 Reagents: Acetic acid ,  Phosphoric acid ,  Hydrogen bromide Solvents: Water
2.1 Reagents: Sodium ethoxide Solvents: Ethanol ,  Nitropropane
2.2 -

Reference

Synthesis and chiral recognition of optically active crown ethers incorporating a helicene moiety as the chiral center

Yamamoto, Koji; et al, Journal of the Chemical Society, 1990, (2), 271-6

4-Bromo-2,5-dimethylbenzaldehyde Raw materials

• 1,4-Dibromo-2,5-dimethylbenzene
• Benzene, 1-bromo-4-(bromomethyl)-2,5-dimethyl-
• piperidine-1-carbaldehyde
• 2,5-Dimethylbromobenzene
• Potassium Trifluoromethylborate
• 4-Bromo-3-methylbenzaldehyde

4-Bromo-2,5-dimethylbenzaldehyde Preparation Products

• 4-Bromo-2,5-dimethylbenzaldehyde (88111-74-4)

• 1. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 2. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
• 3. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 4. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 5. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoyl derivatives

• 24078-12-4(4-bromo-2-methyl-benzaldehyde)
• 83647-40-9(3-Bromo-2-methylbenzaldehyde)
• 88174-55-4(Benzaldehyde, 5-bromo-2,3,4-trimethyl-)
• 88174-52-1(Benzaldehyde, 3-bromo-2,4,5,6-tetramethyl-)
• 88174-44-1(4-bromo-2,3,5,6-tetramethylbenzaldehyde)
• 88174-34-9(Benzaldehyde, 2-bromo-3,4,5,6-tetramethyl-)
• 88174-27-0(Benzaldehyde, 3-bromo-2,4,6-trimethyl-)
• 36276-24-1(3-Bromo-4-methylbenzaldehyde)
• 88174-53-2(Benzaldehyde, 2-bromo-4,6-dimethyl-)
• 88174-38-3(Benzaldehyde, 6-bromo-2,3,4-trimethyl-)