Production Method 1

55715-03-2

88089-94-5

Reaction Conditions

1.1 Reagents: 1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide

Reference

Synthesis and evaluation of the anti parasitic activity of aromatic nitro compounds

Lopes, Marcela S.; Pietra, Renata C. C. de Souza; Borgati, Tatiane F.; Romeiro, Carla F. D.; Junior, Policarpo A. S.; et al, European Journal of Medicinal Chemistry, 2011, 46(11), 5443-5447

Production Method 2

55715-03-2

18107-18-1

88089-94-5

Reaction Conditions

1.1 Solvents: Methanol ,  Benzene ;  25 °C

Reference

Solid-Phase Synthesis of Phenolic Steroids: From Optimization Studies to a Convenient Procedure for Combinatorial Synthesis of Biologically Relevant Estradiol Derivatives

Tremblay, Martin R.; Poirier, Donald, Journal of Combinatorial Chemistry, 2000, 2(1), 48-65

Production Method 3

55715-03-2

88089-94-5

Reaction Conditions

1.1 Reagents: Diisopropylethylamine ,  Thionyl chloride Solvents: Dichloromethane ;  5 min, 0 °C
1.2 4 h, 0 °C

Reference

Enantiospecific Synthesis of Imidazoquinazolin-2-ones via Base-Catalyzed Tandem Cyclization

Kumar, Sunil; Ho, Pei-Heng; Barve, Indrajeet J.; Sun, Chung-Ming, ChemistrySelect, 2017, 2(28), 8917-8921

Production Method 4

2417-72-3

88089-94-5

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  Nitric acid Solvents: Water ;  rt; 5 °C; 30 min, 5 °C
1.2 Reagents: Water ;  cooled

Reference

Synthesis of fluorescence indicator indo-1

Xu, Ruo-qian; Guo, Yuan; Song, Dan-mei; He, Huai-zhen; Chen, Kang-yu, Hecheng Huaxue, 2008, 16(5), 503-507

Production Method 5

7356-11-8

88089-94-5

Reaction Conditions

1.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Carbon tetrachloride ;  overnight, rt → reflux

Reference

Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis

Ye, Yuxuan ; Kevlishvili, Ilia; Feng, Sheng ; Liu, Peng ; Buchwald, Stephen L., Journal of the American Chemical Society, 2020, 142(23), 10550-10556

Production Method 6

2417-72-3

88089-94-5

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  Nitric acid Solvents: Water

Reference

On the reaction of fused benzodiazepines with alkynes containing electron-withdrawing groups

Voskressensky, L. G.; Borisova, T. N.; Babakhanova, M. I.; Akbulatov, S. V.; Tsar'kova, A. S.; et al, Russian Chemical Bulletin, 2012, 61(6), 1220-1230

Methyl 4-(bromomethyl)-3-nitrobenzoate Raw materials

• Methyl 4-methyl-3-nitrobenzoate
• Methyl 4-(bromomethyl)benzoate
• 4-(Bromomethyl)-3-nitrobenzoic acid
• (diazomethyl)trimethylsilane

Methyl 4-(bromomethyl)-3-nitrobenzoate Preparation Products

• Methyl 4-(bromomethyl)-3-nitrobenzoate (88089-94-5)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzoic acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Nitrobenzoic acids and derivatives

• 916791-27-0(3-Bromomethyl-4-Nitro-Benzoic Acid)
• 61940-21-4(2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester)
• 88071-91-4(Methyl 5-(bromomethyl)-2-nitrobenzoate)
• 98475-07-1(2-(Bromomethyl)-3-nitrobenzoic Acid Methyl Ester)
• 7356-11-8(Methyl 4-methyl-3-nitrobenzoate)
• 142051-43-2(Benzoic acid, 4-(bromomethyl)-2-nitro-, methyl ester)
• 132874-06-7(Methyl 3-(bromomethyl)-2-nitrobenzoate)
• 88071-90-3(Methyl 3-(Bromomethyl)-4-nitrobenzoate)
• 55715-03-2(4-(Bromomethyl)-3-nitrobenzoic acid)
• 153754-31-5(Methyl 2-(bromomethyl)-3,5-dinitrobenzoate)