Production Method 1

1066-26-8

24293-28-5

87462-63-3

Reaction Conditions

1.1 Solvents: Dimethylformamide ,  Toluene ;  overnight, rt

Reference

Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands

Peng, Xin; et al, Bioorganic & Medicinal Chemistry Letters, 2015, 25(3), 519-523

Production Method 2

1002-36-4

87462-63-3

Reaction Conditions

1.1 Reagents: Potassium hydride Solvents: 1,3-Propanediamine ,  Tetrahydrofuran ;  rt; 24 h, rt
2.1 Reagents: Potassium hydroxide Solvents: Diethyl ether ;  rt → 0 °C; 6 h, 0 °C
2.2 Reagents: Water ;  cooled

Reference

Cyclization of gold acetylides: Synthesis of vinyl sulfonates via gold vinylidene complexes

Bucher, Janina; et al, Angewandte Chemie, 2014, 53(15), 3854-3858

Production Method 3

63478-76-2

87462-63-3

Reaction Conditions

1.1 Reagents: Triethylamine Catalysts: 4-(Dimethylamino)pyridine Solvents: Dichloromethane ;  overnight, rt

Reference

Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders

Su, Shang ; et al, Journal of Medicinal Chemistry, 2019, 62(16), 7575-7582

Production Method 4

63478-76-2

87462-63-3

Reaction Conditions

1.1 Reagents: Triethylamine Catalysts: 4-(Dimethylamino)pyridine

Reference

Fused ring aziridines as a facile entry into triazole fused tricyclic and bicyclic heterocycles

Fang, Fang; et al, Organic & Biomolecular Chemistry, 2012, 10(15), 3080-3091

Production Method 5

111-29-5

87462-63-3

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  0 °C → rt; 12 h, rt
2.1 Solvents: Dimethylformamide ,  Toluene ;  overnight, rt

Reference

Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands

Peng, Xin; et al, Bioorganic & Medicinal Chemistry Letters, 2015, 25(3), 519-523

Production Method 6

14916-79-1

87462-63-3

Reaction Conditions

1.1 Reagents: Ethylenediamine ,  Sodium hydride
2.1 Reagents: Triethylamine Catalysts: 4-(Dimethylamino)pyridine

Reference

Fused ring aziridines as a facile entry into triazole fused tricyclic and bicyclic heterocycles

Fang, Fang; et al, Organic & Biomolecular Chemistry, 2012, 10(15), 3080-3091

6-Heptyn-1-ol, 4-methylbenzenesulfonate Raw materials

• 2-Heptyn-1-ol
• pentane-1,5-diol
• hept-6-yn-1-ol
• Sodium Acetylide Suspension (18 wt. % slurry in xylene)
• 1,5-Pentanediol,1,5-bis(4-methylbenzenesulfonate)
• 3-Heyptyn-1-ol

6-Heptyn-1-ol, 4-methylbenzenesulfonate Preparation Products

• 6-Heptyn-1-ol, 4-methylbenzenesulfonate (87462-63-3)

• 1. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
• 2. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 3. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
• 4. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 5. Excited state dynamics of symmetric and asymmetric Cr3(dpa)4Cl2 measured using femtosecond transient absorption spectroscopy?
  Chao-Han Cheng,Wen-Zhen Wang,Shie-Ming Peng,I-Chia Chen Phys. Chem. Chem. Phys., 2017,19, 25471-25477

• 4450-76-4(Benzenesulfonic acid,4-methyl-, pentyl ester)
• 3839-35-8(Hexyl p-Toluenesulfonate)
• 40235-95-8(1,7-Heptanediol,1,7-bis(4-methylbenzenesulfonate))
• 77758-50-0(4-Pentynyl p-Tosylate, 90%)
• 73992-42-4(1,9-Nonanediol, 1,9-bis(4-methylbenzenesulfonate))
• 10157-76-3(Dodecyl p-Toluenesulfonate)
• 3386-32-1(Octadecyl p-Toluenesulfonate)
• 3386-35-4(n-Octyl-p-Toluenesulfonate)
• 24293-28-5(1,5-Pentanediol,1,5-bis(4-methylbenzenesulfonate))
• 5509-08-0(Benzenesulfonic acid, 4-methyl-, decyl ester)