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• 2. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Halobenzoic acids and derivatives
• Other Chemical Reagents Derivatization Reagents
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

Comprehensive Overview of 4-Borono-3-fluorobenzamide (CAS No. 874289-22-2): Properties, Applications, and Research Insights

4-Borono-3-fluorobenzamide (CAS No. 874289-22-2) is a specialized boronic acid derivative with significant potential in pharmaceutical and chemical research. This compound, characterized by its unique fluorobenzamide and boronate functional groups, has garnered attention for its role in Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern organic synthesis. Researchers and industry professionals are increasingly exploring its applications in drug discovery, bioconjugation, and material science, making it a subject of growing interest in academic and industrial settings.

The molecular structure of 4-Borono-3-fluorobenzamide combines a benzamide scaffold with a boronic acid moiety, enabling versatile reactivity. This design facilitates its use as a building block for complex molecules, particularly in the development of targeted therapeutics. Recent studies highlight its utility in proteolysis-targeting chimeras (PROTACs), a cutting-edge approach in cancer therapy. The fluorine atom enhances metabolic stability, while the boron group allows for precise molecular recognition, addressing key challenges in precision medicine.

In the context of green chemistry, 4-Borono-3-fluorobenzamide aligns with the demand for sustainable synthetic methods. Its compatibility with aqueous reaction conditions and low-toxicity catalysts positions it as an eco-friendly alternative in industrial-scale synthesis. Searches for "boronic acid derivatives in drug development" and "fluorinated benzamide applications" have surged, reflecting its relevance in solving bioavailability and selectivity issues in small-molecule drugs.

From a technical perspective, the compound’s crystalline form and solubility profile are critical for formulation scientists. Analytical techniques like NMR spectroscopy and HPLC purity testing are routinely employed to ensure quality. Discussions on platforms such as ResearchGate and PubMed frequently address its stability under physiological conditions, a hot topic for researchers optimizing drug delivery systems.

Market trends indicate rising demand for 4-Borono-3-fluorobenzamide in contract research organizations (CROs) and academic labs. Queries like "CAS 874289-22-2 supplier" and "boronic acid cross-coupling protocols" dominate search engines, underscoring its commercial and scientific value. Innovations in high-throughput screening further amplify its role in identifying novel enzyme inhibitors, particularly for kinase-targeted therapies.

Future directions for 874289-22-2 include exploring its biocompatibility in nanomedicine and theranostic agents. As the scientific community prioritizes personalized treatment, this compound’s modular design offers a template for next-generation diagnostics. Its integration into AI-driven drug design workflows, a trending topic in computational chemistry, exemplifies its cross-disciplinary impact.

• 874288-39-8((4-Carbamoyl-3-fluorophenyl)boronic acid)
• 874219-34-8(3-Carbamoyl-4-fluorophenylboronic acid)
• 871126-22-6((2-fluoro-4-formylphenyl)boronic acid)
• 874289-45-9(N-Ethyl 3-borono-4-fluorobenzamide)
• 874289-53-9(N-Benzyl 3-borono-4-fluorobenzamide)
• 352534-79-3(2-Fluoro-5-formylphenylboronic acid)
• 874289-39-1((5-Carbamoyl-2-fluorophenyl)boronic acid)
• 874289-40-4((2-Fluoro-5-(methylcarbamoyl)phenyl)boronic acid)
• 874289-47-1(N,N-Diethyl 3-borono-4-fluorobenzamide)
• 874289-56-2(3-Borono-4-fluorobenzohydrazide)