Production Method 1

5470-18-8

14092-04-7

874013-97-5

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  -78 °C; 18 h, -20 °C; -20 °C → rt

Reference

Molecular modeling, design, synthesis, and biological activity of 1H-pyrrolo[2,3-c]pyridine-7-amine derivatives as potassium-competitive acid blockers

Arikawa, Yasuyoshi; Hasuoka, Atsushi; Hirase, Keizo; Inatomi, Nobuhiro; Sato, Fumihiko; et al, Chemical & Pharmaceutical Bulletin, 2014, 62(4), 336-342

7-Chloro-2-methyl-1H-pyrrolo[2,3-C]pyridine Raw materials

• 2-chloro-3-nitro-pyridine
• 1-Propenylmagnesium bromide

7-Chloro-2-methyl-1H-pyrrolo[2,3-C]pyridine Preparation Products

• 7-Chloro-2-methyl-1H-pyrrolo[2,3-C]pyridine (874013-97-5)

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• Solvents and Organic Chemicals Organic Compounds

• 357263-41-3(7-Chloro-1H-pyrrolo[2,3-c]pyridine)
• 930790-43-5(7-Chloro-5-methyl-1H-pyrrolo[2,3-c]pyridine)
• 13058-77-0(8-Chloro-1,7-naphthyridine)
• 874013-98-6(1H-Pyrrolo[2,3-c]pyridine, 7-chloro-2,3-dimethyl-)
• 102337-43-9(1-chloro-9H-Pyrido[3,4-b]indole)
• 854018-87-4(4-chloro-2-methyl-1H-Pyrrolo[3,2-c]pyridine)
• 930790-54-8(5-chloro-7-methyl-1H-Pyrrolo[2,3-c]pyridine)
• 930302-88-8(8-chloro-2-methyl-1,7-Naphthyridine)
• 1158715-33-3(5,7-dichloro-2,3-dimethyl-1H-Pyrrolo[2,3-c]pyridine)
• 1001412-41-4(5,7-Dichloro-1H-pyrrolo[2,3-C]pyridine)