Production Method 1

872460-12-3

10017-11-5

872460-12-3

Reaction Conditions

1.1 Reagents: N-Hydroxysuccinimide ,  1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride Solvents: Dimethylformamide ,  Water ;  15 min, rt
1.2 Reagents: Sodium hydroxide Solvents: Water ;  24 h, rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  7 d, rt

Reference

Cross-Linking-Density-Changeable Microneedle Patch Prepared from a Glucose-Responsive Hydrogel for Insulin Delivery

Chen, Xiang; et al, ACS Biomaterials Science & Engineering, 2021, 7(10), 4870-4882

Production Method 2

13590-42-6

80506-64-5

872460-12-3

Reaction Conditions

1.1 Solvents: Dimethylformamide ,  Dichloromethane ;  48 h, 35 °C
2.1 Solvents: N-Methyl-2-pyrrolidone ;  1 h, 0 °C
2.2 Reagents: Acetic acid Solvents: Water ;  neutralized, 0 °C
3.1 Reagents: Sodium hydroxide ,  1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide ,  N-Hydroxysuccinimide Solvents: Water ;  1 h, pH 5.5, rt
3.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 5.5 - 6, rt; 24 h, rt

Reference

ATP-Charged Nanoclusters Enable Intracellular Protein Delivery and Activity Modulation for Cancer Theranostics

Zhou, Zhanwei; et al, iScience, 2020, 23(2),

Production Method 3

872460-12-3

2177-63-1

75-21-8

872460-12-3

Reaction Conditions

1.1 Reagents: Sodium hydroxide ,  1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide ,  N-Hydroxysuccinimide Solvents: Water ;  1 h, pH 5.5, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 5.5 - 6, rt; 24 h, rt

Reference

ATP-Charged Nanoclusters Enable Intracellular Protein Delivery and Activity Modulation for Cancer Theranostics

Zhou, Zhanwei; et al, iScience, 2020, 23(2),

Production Method 4

2177-63-1

75-21-8

872460-12-3

Reaction Conditions

1.1 Solvents: N-Methyl-2-pyrrolidone ;  1 h, 0 °C
1.2 Reagents: Acetic acid Solvents: Water ;  neutralized, 0 °C
2.1 Reagents: Sodium hydroxide ,  1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide ,  N-Hydroxysuccinimide Solvents: Water ;  1 h, pH 5.5, rt
2.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 5.5 - 6, rt; 24 h, rt

Reference

ATP-Charged Nanoclusters Enable Intracellular Protein Delivery and Activity Modulation for Cancer Theranostics

Zhou, Zhanwei; et al, iScience, 2020, 23(2),

3-Carboxy-4-fluorophenylboronic acid Raw materials

• b-Benzyl L-Aspartic Acid N-carboxyanhydride
• 3-Carboxy-4-fluorophenylboronic acid
• Prop-2-en-1-amine Hydrochloride
• L-Aspartic acid 4-benzyl ester
• Ethylene Oxide
• MPEG-NH2

3-Carboxy-4-fluorophenylboronic acid Preparation Products

• 3-Carboxy-4-fluorophenylboronic acid (872460-12-3)

• 1. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 2. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 3. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
• 4. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Halobenzoic acids and derivatives
• Other Chemical Reagents Derivatization Reagents
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

• 374538-01-9(4-Fluoro-3-formylphenylboronic acid)
• 874219-59-7(5-Carboxy-2-fluorophenylboronic acid)
• 120153-08-4(4-Carboxy-3-fluorophenylboronic acid)
• 874219-36-0((3-(Ethoxycarbonyl)-4-fluorophenyl)boronic acid)
• 505083-04-5([3-fluoro-4-(methoxycarbonyl)phenyl]boronic acid)
• 874219-35-9((4-fluoro-3-methoxycarbonylphenyl)boronic acid)
• 874288-38-7(4-Ethoxycarbonyl-3-fluorophenylboronic acid)
• 481681-02-1((4-fluoro-3-(hydroxymethyl)phenyl)boronic acid)
• 248270-25-9(3-Fluoro-4-formylphenylboronic acid)
• 87018-11-9(Cyclopentane,1,1'-(4-pentyl-1,7-heptanediyl)bis- (9CI))