Production Method 1

251554-42-4

870679-59-7

Reaction Conditions

1.1 Reagents: Tin ,  Hydrochloric acid Solvents: Ethanol ,  Water ;  30 min, reflux; reflux → rt
1.2 Reagents: Sodium hydroxide Solvents: Water ;  basified, rt

Reference

Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide

Murineddu, Gabriele; et al, Journal of Medicinal Chemistry, 2005, 48(23), 7351-7362

Production Method 2

251554-42-4

870679-59-7

Reaction Conditions

1.1 Reagents: Tin ,  Hydrochloric acid Solvents: Ethanol ,  Water ;  45 min, 110 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ;  basified, cooled

Reference

Vinyl Carbocations Generated under Basic Conditions and Their Intramolecular C-H Insertion Reactions

Wigman, Benjamin; et al, Journal of the American Chemical Society, 2019, 141(23), 9140-9144

Production Method 3

251554-42-4

870679-59-7

Reaction Conditions

1.1 Reagents: Tin ,  Hydrochloric acid Solvents: Ethanol ,  Water ;  45 min, 110 °C; cooled
1.2 Reagents: Sodium hydroxide Solvents: Water ;  basified

Reference

Strong bases and weak anions in catalytic C-H insertion reactions of vinyl carbocations

Wigman, Benjamin; et al, ChemRxiv, 2018, 1, 1-11

Production Method 4

826-73-3

870679-59-7

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  Potassium nitrate Solvents: Water ;  2 h, -5 °C; 1 h, -5 °C
2.1 Reagents: Tin ,  Hydrochloric acid Solvents: Ethanol ,  Water ;  30 min, reflux; reflux → rt
2.2 Reagents: Sodium hydroxide Solvents: Water ;  basified, rt

Reference

Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide

Murineddu, Gabriele; et al, Journal of Medicinal Chemistry, 2005, 48(23), 7351-7362

1-Amino-6,7,8,9-tetrahydro-5H-benzo7annulen-5-one Raw materials

• 5H-Benzocyclohepten-5-one,6,7,8,9-tetrahydro-1-nitro-
• 6,7,8,9-tetrahydro-5H-benzo7annulen-5-one

1-Amino-6,7,8,9-tetrahydro-5H-benzo7annulen-5-one Preparation Products

• 1-Amino-6,7,8,9-tetrahydro-5H-benzo7annulen-5-one (870679-59-7)

• 1. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
• 2. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 3. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

• 258528-41-5(1(2H)-Naphthalenone,5-amino-3,4-dihydro-8-methyl-)
• 919077-99-9(1H-Inden-1-one, 6-amino-2,3-dihydro-5-methyl-)
• 851107-86-3(4,5-diamino-2,3-dihydroinden-1-one)
• 51135-91-2(4-Amino-1-indanone)
• 210346-49-9(8-amino-3,4-dihydro-2H-naphthalen-1-one;hydrochloride)
• 149026-12-0(4-amino-2,3-dihydro-1H-inden-1-one hydrochloride)
• 149026-14-2(1H-Inden-1-one, 4-amino-2,3-dihydro-6,7-dimethyl-, hydrochloride)
• 149048-40-8(1H-Inden-1-one, 4-amino-2,3-dihydro-6,7-dimethyl-)
• 41823-28-3(5-Amino-3,4-dihydronaphthalen-1(2H)-one)
• 628732-03-6(7-Aminoindan-1-one)