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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyridines Pyrrolopyridines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyridines

Comprehensive Overview of 2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine Dihydrochloride (CAS No. 868173-88-0)

2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine dihydrochloride (CAS No. 868173-88-0) is a chemically synthesized compound that has garnered significant attention in pharmaceutical and biochemical research due to its unique structural properties and potential applications. This compound belongs to the class of heterocyclic amines, specifically featuring a pyrrolopyridine core, which is known for its versatility in drug discovery and development. Researchers are particularly interested in its role as a building block for designing novel therapeutic agents targeting neurological and metabolic disorders.

The molecular structure of 2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine dihydrochloride includes a pyrrolopyridine scaffold coupled with an ethylamine side chain, which enhances its binding affinity to various biological targets. This characteristic makes it a valuable candidate for studying receptor-ligand interactions and signal transduction pathways. Recent studies have explored its potential in modulating G-protein-coupled receptors (GPCRs), a hot topic in modern pharmacology due to their involvement in numerous physiological processes.

In the context of current research trends, 2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine dihydrochloride has been investigated for its possible role in addressing neurodegenerative diseases such as Alzheimer's and Parkinson's. These conditions are among the most searched topics in biomedical research, reflecting global concerns about aging populations. The compound's ability to interact with neurotransmitter systems positions it as a promising subject for further exploration.

Another area of interest is the compound's application in cancer research. The pyrrolopyridine moiety is frequently found in kinase inhibitors, which are pivotal in targeted cancer therapies. Researchers are examining whether derivatives of 2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine dihydrochloride can inhibit specific oncogenic kinases, a question frequently posed in AI-driven drug discovery platforms. This aligns with the growing demand for precision medicine solutions.

From a synthetic chemistry perspective, the preparation of 2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine dihydrochloride involves multi-step organic reactions, including cyclization and amination processes. Its dihydrochloride salt form improves solubility and stability, making it more suitable for in vitro and in vivo studies. These attributes are critical for researchers seeking high-purity compounds for reproducible experiments.

The compound's CAS number (868173-88-0) serves as a unique identifier in chemical databases, facilitating seamless integration into cheminformatics workflows. This is particularly relevant given the rise of computational chemistry tools that rely on accurate chemical descriptors for virtual screening and molecular docking simulations. Such applications are frequently searched by professionals in pharmaceutical R&D.

In summary, 2-(1H-Pyrrolo[3,2-c]pyridin-3-yl)ethanamine dihydrochloride represents a multifaceted compound with broad implications in drug discovery and mechanistic studies. Its structural features and biological relevance make it a subject of ongoing investigation, particularly in areas like neurology, oncology, and enzyme modulation. As research continues, this compound may unlock new avenues for addressing some of the most pressing challenges in modern medicine.

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