Production Method 1

32834-84-7

86631-56-3

Reaction Conditions

1.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  3 h, rt → reflux

Reference

Single-component, low molecular weight organic supergelators based on chiral barbiturate scaffolds

Seidenkranz, Daniel T.; et al, Supramolecular Chemistry, 2019, 31(8), 499-507

Production Method 2

32834-84-7

86631-56-3

Reaction Conditions

1.1 Reagents: Benzoyl peroxide ,  N-Bromosuccinimide Solvents: Carbon tetrachloride
2.1 Solvents: Benzene ,  Acetonitrile
3.1 Reagents: Nickel dichloride ,  Lithium aluminum hydride Solvents: Tetrahydrofuran
4.1 Reagents: Benzoyl peroxide ,  N-Bromosuccinimide Solvents: Carbon tetrachloride

Reference

New and improved synthesis of optically pure (R)- and (S)-2,2'-dimethyl-1,1'-binaphthyl and related compounds

Maigrot, Nicole; et al, Synthesis, 1985, (3), 317-20

Production Method 3

126613-06-7

86631-56-3

Reaction Conditions

1.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ;  0 °C; 18 h, 20 °C
2.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Carbon tetrachloride ;  2 h, reflux

Reference

Organocatalytic Enantioselective Synthesis of Bicyclo[2.2.2]octenones via Oxaziridinium Catalysed ortho-Hydroxylative Phenol Dearomatization

D'Arcy, Tom D. ; et al, Angewandte Chemie, 2022, 61(30),

Production Method 4

917-64-6

126613-06-7

86631-56-3

Reaction Conditions

1.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ;  rt → 0 °C; 0 °C; 0 °C → reflux; 19 h, reflux; reflux → 0 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  0 °C
2.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  3 h, rt → reflux

Reference

Single-component, low molecular weight organic supergelators based on chiral barbiturate scaffolds

Seidenkranz, Daniel T.; et al, Supramolecular Chemistry, 2019, 31(8), 499-507

Production Method 5

128575-34-8

917-64-6

86631-56-3

Reaction Conditions

1.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ,  Tetrahydrofuran ;  0 °C; 6 h, 80 °C
1.2 Reagents: Ammonium chloride Solvents: Water
2.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  12 h, 80 °C
2.2 Reagents: Water

Reference

Investigation of the interaction between a novel unnatural chiral ligand and reactant on palladium for asymmetric hydrogenation

Jeon, Eun Hee; et al, Physical Chemistry Chemical Physics, 2015, 17(27), 17771-17777

Production Method 6

2586-62-1

21450-90-8

86631-56-3

Reaction Conditions

1.1 Catalysts: Nickel bromide ,  (1S)-1-(Diphenylphosphino)-2-[(1S)-1-methoxyethyl]ferrocene Solvents: Diethyl ether
2.1 Reagents: Benzoyl peroxide ,  N-Bromosuccinimide Solvents: Carbon tetrachloride

Reference

Asymmetric synthesis catalyzed by chiral ferrocenylphosphine-transition-metal complexes. 6. Practical asymmetric synthesis of 1,1'-binaphthyls via asymmetric cross-coupling with a chiral [(alkoxyalkyl)ferrocenyl]monophosphine/nickel catalyst

Hayashi, Tamio; et al, Journal of the American Chemical Society, 1988, 110(24), 8153-6

Production Method 7

2862113-80-0

3378-82-3

86631-56-3

Reaction Conditions

1.1 Reagents: Tetrabutylammonium iodide ,  Zinc Catalysts: Bis(triphenylphosphine)nickel dichloride ,  2764676-49-3 Solvents: N-Methyl-2-pyrrolidone ;  16 h, 45 °C
2.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, 0 °C
2.2 Reagents: Phosphorus tribromide Solvents: Tetrahydrofuran ;  2 h, 0 °C

Reference

Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho-Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2'-Bipyridine Ligand

Perveen, Saima; et al, Angewandte Chemie, 2022, 61(47),

Production Method 8

86631-57-4

86631-56-3

Reaction Conditions

1.1 Reagents: Nickel dichloride ,  Lithium aluminum hydride Solvents: Tetrahydrofuran
2.1 Reagents: Benzoyl peroxide ,  N-Bromosuccinimide Solvents: Carbon tetrachloride

Reference

New and improved synthesis of optically pure (R)- and (S)-2,2'-dimethyl-1,1'-binaphthyl and related compounds

Maigrot, Nicole; et al, Synthesis, 1985, (3), 317-20

Production Method 9

18531-94-7

358-23-6

86631-56-3

Reaction Conditions

1.1 Reagents: Triethylamine ,  4-(Dimethylamino)pyridine ;  0 °C; 1 h, 20 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  20 °C
2.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ;  0 °C; 18 h, 20 °C
3.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Carbon tetrachloride ;  2 h, reflux

Reference

Organocatalytic Enantioselective Synthesis of Bicyclo[2.2.2]octenones via Oxaziridinium Catalysed ortho-Hydroxylative Phenol Dearomatization

D'Arcy, Tom D. ; et al, Angewandte Chemie, 2022, 61(30),

Production Method 10

18531-94-7

358-23-6

86631-56-3

Reaction Conditions

1.1 Reagents: Pyridine Solvents: Dichloromethane ;  rt
1.2 0 °C; 5 h, rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  0 °C
2.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ;  30 min, 0 °C; 20 h, reflux; reflux → rt
2.2 Reagents: Hydrochloric acid Solvents: Water ;  0 °C
3.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Carbon tetrachloride ;  rt; 2 h, reflux

Reference

Design of Phosphinic Acid Catalysts with the Closest Stereogenicity at the α-Position: Synthesis and Application of α-Stereogenic Perfluoroalkyl Phosphinic Acid Catalysts

Fujii, Kohei; et al, Organic Letters, 2019, 21(9), 3387-3391

Production Method 11

86631-56-3

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, 0 °C
1.2 Reagents: Phosphorus tribromide Solvents: Tetrahydrofuran ;  2 h, 0 °C

Reference

Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho-Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2'-Bipyridine Ligand

Perveen, Saima; et al, Angewandte Chemie, 2022, 61(47),

Production Method 12

19634-89-0

86631-56-3

Reaction Conditions

1.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Cyclohexane ;  5 h, rt

Reference

Iminium salt catalysts for asymmetric epoxidation: the first high enantioselectivities

Bulman Page, Philip C.; et al, Organic Letters, 2004, 6(10), 1543-1546

Production Method 13

76373-22-3

86631-56-3

Reaction Conditions

1.1 Reagents: Carbon tetrabromide ,  Triphenylphosphine Solvents: Dichloromethane

Reference

Synthesis of axially dissymmetric chiral ammonium salts by quaternization of secondary amines with (R)-(+)-2,2'-bis(bromomethyl)-6,6'-dinitrobiphenyl and (R)-(+)-2,2'-bis(bromomethyl)-1,1'-binaphthyl and an examination of their abilities as chiral phase-transfer catalysts

Shi, Min; et al, Journal of Chemical Research, 1995, (2), 46-7

Production Method 14

126613-06-7

86631-56-3

Reaction Conditions

1.1 Reagents: Magnesium ,  Iodine Solvents: tert-Butyl methyl ether ;  5 min, rt
1.2 Solvents: tert-Butyl methyl ether ;  rt; 15 min, rt; 30 min, reflux
1.3 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: tert-Butyl methyl ether ;  55 °C; 45 min, 55 °C; 55 °C → rt; 18 h, rt; rt → 4 °C
1.4 Reagents: Hydrochloric acid Solvents: Toluene ,  Water ;  < 10 °C; 18 h, rt
2.1 Reagents: 1,3-Dibromo-5,5-dimethylhydantoin Solvents: Ethyl acetate ;  15 min, rt
2.2 Catalysts: Azobisisobutyronitrile ;  rt → 65 °C; 3.5 h, 65 °C; 65 °C → 25 °C
2.3 Solvents: Water ;  18 h, rt; 1 h, rt → 1.5 °C

Reference

Large Scale Synthesis of Chiral (3Z,5Z)-2,7-Dihydro-1H-azepine-Derived Hamari Ligand for General Asymmetric Synthesis of Tailor-Made Amino Acids

Takahashi, Motohiro ; et al, Organic Process Research & Development, 2019, 23(4), 619-628

Production Method 15

126613-06-7

86631-56-3

Reaction Conditions

1.1 Reagents: Magnesium Solvents: tert-Butyl methyl ether ;  rt
1.2 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel ;  rt → 35 °C
1.3 Solvents: tert-Butyl methyl ether ;  35 °C → reflux; 1 h, reflux
1.4 Reagents: Hydrochloric acid Solvents: Water ;  acidified
2.1 Reagents: Azobisisobutyronitrile ,  N-Bromosuccinimide Solvents: Cyclohexane ;  rt → reflux; 3 h, reflux

Reference

Asymmetric Henry reaction catalyzed by CuOTf/NNN tridentate pincer ligand

Xu, Shanshan; et al, Youji Huaxue, 2012, 32(6), 1131-1135

Production Method 16

126613-06-7

86631-56-3

Reaction Conditions

1.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ;  30 min, 0 °C; 20 h, reflux; reflux → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  0 °C
2.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Carbon tetrachloride ;  rt; 2 h, reflux

Reference

Design of Phosphinic Acid Catalysts with the Closest Stereogenicity at the α-Position: Synthesis and Application of α-Stereogenic Perfluoroalkyl Phosphinic Acid Catalysts

Fujii, Kohei; et al, Organic Letters, 2019, 21(9), 3387-3391

Production Method 17

917-64-6

126613-06-7

86631-56-3

Reaction Conditions

1.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: tert-Butyl methyl ether ;  30 min, reflux
2.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Hexane ;  rt; 2 h, reflux

Reference

A Scalable Synthesis of (R)-3,5-Dihydro-4H-dinaphth[2,1-c:1'2'-e]azepine

Ikunaka, Masaya; et al, Organic Process Research & Development, 2003, 7(5), 644-648

Production Method 18

14304-75-7

86631-56-3

Reaction Conditions

1.1 Reagents: Zinc Catalysts: Bis(triphenylphosphine)nickel dichloride ,  2764676-49-3 Solvents: N-Methyl-2-pyrrolidone ;  16 h, 45 °C
2.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, 0 °C
2.2 Reagents: Phosphorus tribromide Solvents: Tetrahydrofuran ;  2 h, 0 °C

Reference

Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho-Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2'-Bipyridine Ligand

Perveen, Saima; et al, Angewandte Chemie, 2022, 61(47),

Production Method 19

917-64-6

18531-94-7

86631-56-3

Reaction Conditions

1.1 Reagents: Triethylamine ,  Trifluoromethanesulfonic anhydride Solvents: Dichloromethane ;  -78 °C; 3 h, -78 °C; -78 °C → 0 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water
1.3 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ,  Tetrahydrofuran ;  0 °C; 6 h, 80 °C
1.4 Reagents: Ammonium chloride Solvents: Water
2.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  12 h, 80 °C
2.2 Reagents: Water

Reference

Investigation of the interaction between a novel unnatural chiral ligand and reactant on palladium for asymmetric hydrogenation

Jeon, Eun Hee; et al, Physical Chemistry Chemical Physics, 2015, 17(27), 17771-17777

Production Method 20

3378-82-3

86631-56-3

Reaction Conditions

1.1 Reagents: Zinc Catalysts: Bis(triphenylphosphine)nickel dichloride ,  2764676-49-3 Solvents: N-Methyl-2-pyrrolidone ;  16 h, 45 °C
2.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, 0 °C
2.2 Reagents: Phosphorus tribromide Solvents: Tetrahydrofuran ;  2 h, 0 °C

Reference

Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho-Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2'-Bipyridine Ligand

Perveen, Saima; et al, Angewandte Chemie, 2022, 61(47),

Production Method 21

80703-23-7

86631-56-3

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Diethyl ether
2.1 Reagents: Carbon tetrabromide ,  Triphenylphosphine Solvents: Dichloromethane

Reference

Synthesis of axially dissymmetric chiral ammonium salts by quaternization of secondary amines with (R)-(+)-2,2'-bis(bromomethyl)-6,6'-dinitrobiphenyl and (R)-(+)-2,2'-bis(bromomethyl)-1,1'-binaphthyl and an examination of their abilities as chiral phase-transfer catalysts

Shi, Min; et al, Journal of Chemical Research, 1995, (2), 46-7

Production Method 22

18531-94-7

37595-74-7

86631-56-3

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Solvents: Dimethylformamide ;  24 h, rt
2.1 Catalysts: Dichloro[1,1′-(1,3-propanediyl)bis[1,1-diphenylphosphine-κP]]nickel Solvents: Diethyl ether ;  rt → 0 °C; 0 °C; 0 °C → reflux; 19 h, reflux; reflux → 0 °C
2.2 Reagents: Hydrochloric acid Solvents: Water ;  0 °C
3.1 Reagents: N-Bromosuccinimide Catalysts: Azobisisobutyronitrile Solvents: Benzene ;  3 h, rt → reflux

Reference

Single-component, low molecular weight organic supergelators based on chiral barbiturate scaffolds

Seidenkranz, Daniel T.; et al, Supramolecular Chemistry, 2019, 31(8), 499-507

Production Method 23

54130-90-4

86631-56-3

Reaction Conditions

1.1 Solvents: Benzene ,  Acetonitrile
2.1 Reagents: Nickel dichloride ,  Lithium aluminum hydride Solvents: Tetrahydrofuran
3.1 Reagents: Benzoyl peroxide ,  N-Bromosuccinimide Solvents: Carbon tetrachloride

Reference

New and improved synthesis of optically pure (R)- and (S)-2,2'-dimethyl-1,1'-binaphthyl and related compounds

Maigrot, Nicole; et al, Synthesis, 1985, (3), 317-20

Production Method 24

68498-84-0

32281-97-3

86631-56-3

Reaction Conditions

1.1 Reagents: Tripotassium phosphate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: Toluene ;  3 h, 100 °C
1.2 Reagents: Phosphorus oxychloride ;  0 °C; 15 min, 0 °C
1.3 Solvents: Dimethylformamide ;  0 °C; 0 °C → 60 °C; 6 h, 60 °C
1.4 Reagents: Sodium bicarbonate Solvents: Water ;  pH 6, cooled
1.5 Reagents: 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone Solvents: Chlorobenzene ;  72 h, reflux
2.1 Reagents: Tetrabutylammonium iodide ,  Zinc Catalysts: Bis(triphenylphosphine)nickel dichloride ,  2764676-49-3 Solvents: N-Methyl-2-pyrrolidone ;  16 h, 45 °C
3.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, 0 °C
3.2 Reagents: Phosphorus tribromide Solvents: Tetrahydrofuran ;  2 h, 0 °C

Reference

Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho-Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2'-Bipyridine Ligand

Perveen, Saima; et al, Angewandte Chemie, 2022, 61(47),

1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- Raw materials

• 1-Chloro-7-methoxy-2-naphthalenecarboxaldehyde
• boric acid-carbon
• (R)-2,2'-Dimethyl-1,1'-binaphthyl
• 1,1'-binaphthalene, 2,2'-dimethyl-
• 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-
• 7-Bromo-1-tetralone
• Methanesulfonic acid,1,1,1-trifluoro-, 1,1'-[1,1'-binaphthalene]-2,2'-diyl ester
• [1,1'-Binaphthalene]-2,2'-dicarboxylicacid, (1R)-
• Methylmagnesium Iodide (3.0 M in Diethyl ether)
• (R)-1,1'-Binaphthalene-2,2'-diyl Bis(trifluoromethanesulfonate)
• (1R)-[1,1'-Binaphthalene]-2,2'-diol
• N,N-Bis(trifluoromethylsulfonyl)aniline
• Trifluoromethanesulfonic Anhydride
• 1-Bromo-2-naphthaldehyde
• 1-Bromo-2-methylnaphthalene
• Magnesium,bromo(2-methyl-1-naphthalenyl)-
• 2-Naphthalenecarboxaldehyde,1-chloro-
• 1,1'-Binaphthyl-2,2'-dimethanol
• 3H-Dinaphth[2,1-c:1′,2′-e]azepinium, 4,5-dihydro-4-[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]-4-methyl-, bromide, (11bR)-

1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- Preparation Products

• 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- (86631-56-3)

• 1. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
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• 2. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
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• 3. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
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• 4. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
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• 5. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212

• Catalysts and Inorganic Chemicals Catalysts

Recent Advances in the Application of 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- (CAS: 86631-56-3) in Chemical Biology and Pharmaceutical Research

The compound 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- (CAS: 86631-56-3) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its unique structural properties and versatile applications. This chiral binaphthyl derivative serves as a crucial intermediate in the synthesis of complex molecules, particularly in asymmetric catalysis and drug development. Recent studies have highlighted its potential in constructing novel chiral ligands, catalysts, and bioactive compounds, making it a focal point for researchers aiming to develop enantioselective synthetic methodologies and therapeutic agents.

One of the most notable advancements involves the use of 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- as a precursor for the synthesis of chiral phosphine ligands. These ligands have demonstrated exceptional efficacy in asymmetric hydrogenation reactions, a critical process in the production of enantiomerically pure pharmaceuticals. For instance, a 2023 study published in Journal of the American Chemical Society reported the development of a new class of binaphthyl-based phosphine ligands derived from this compound, achieving over 99% enantiomeric excess (ee) in the hydrogenation of α,β-unsaturated carboxylic acids. This breakthrough underscores the compound's pivotal role in advancing green and sustainable synthetic chemistry.

In addition to its applications in catalysis, 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- has been explored for its potential in drug discovery. Researchers have utilized its rigid, chiral framework to design small-molecule inhibitors targeting protein-protein interactions (PPIs). A recent study in Nature Chemical Biology detailed the synthesis of a library of binaphthyl-derived compounds, including derivatives of 86631-56-3, which exhibited potent inhibitory activity against the p53-MDM2 interaction—a key target in cancer therapy. The study highlighted the compound's ability to impart high binding affinity and selectivity, paving the way for novel anticancer agents.

Further investigations have also revealed the compound's utility in materials science, particularly in the development of chiral organic frameworks (COFs) and liquid crystals. Its bromomethyl groups provide reactive sites for post-synthetic modifications, enabling the construction of functional materials with tailored properties. A 2023 Advanced Materials publication demonstrated the incorporation of 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- into a COF structure, resulting in a material with exceptional chiral recognition capabilities for use in enantioselective separations.

Despite these promising developments, challenges remain in the large-scale synthesis and purification of 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)-. Recent efforts have focused on optimizing synthetic routes to improve yield and enantiopurity. For example, a 2024 Organic Process Research & Development article described a scalable, cost-effective method for its production using continuous flow chemistry, addressing previous limitations in batch processing. Such innovations are critical for translating laboratory-scale discoveries into industrial applications.

In conclusion, 1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-, (1R)- (CAS: 86631-56-3) continues to be a cornerstone in chemical biology and pharmaceutical research, with its applications spanning asymmetric synthesis, drug discovery, and materials science. Ongoing research is expected to further unlock its potential, particularly in addressing unmet medical needs and advancing sustainable chemistry. Future directions may include exploring its use in biocatalysis and the development of next-generation chiral materials, solidifying its position as a versatile and indispensable tool in modern science.

• 88986-01-0(Phenanthrene, 9-[2-(bromomethyl)phenyl]-)
• 135325-62-1(Fluoranthene,1-(bromomethyl)-)
• 54130-90-4(1,1'-Binaphthalene, 2,2'-bis(bromomethyl)-)
• 104463-80-1(Anthracene, 9-[2,6-bis(bromomethyl)phenyl]-)
• 138982-82-8(Fluoranthene, 1,6,7,10-tetrakis(bromomethyl)-)
• 80603-34-5(Phenanthrene, 9-[2-(bromomethyl)-1-naphthalenyl]-)
• 61684-55-7(Naphthalene, 2-[(bromomethyl)phenyl]-)
• 77061-07-5(Fluoranthene,7-(bromomethyl)-)
• 662143-35-3(Naphthalene, 1-[2,6-bis(bromomethyl)phenyl]-)
• 37803-02-4(2-(Bromomethyl)-1-[2-(bromomethyl)naphthalen-1-yl]naphthalene)