Production Method 1

2546-56-7

860296-20-4

Reaction Conditions

1.1 Reagents: Diisopropylamine ,  Butyllithium Solvents: Tetrahydrofuran ,  Hexane ;  20 h, -75 °C
1.2 -
1.3 Reagents: Hydrochloric acid Solvents: Water ;  rt

Reference

Converting core compounds into building blocks: The concept of regiochemically exhaustive functionalization

Marzi, Elena; Bobbio, Carla; Cottet, Fabrice; Schlosser, Manfred, European Journal of Organic Chemistry, 2005, (10), 2116-2123

Production Method 2

2546-56-7

860296-20-4

860296-21-5

Reaction Conditions

1.1 Reagents: Diisopropylamine ,  Butyllithium Solvents: Tetrahydrofuran ,  Hexane ;  10 min, -75 °C
1.2 -
1.3 Reagents: Hydrochloric acid Solvents: Water ;  rt

Reference

Converting core compounds into building blocks: The concept of regiochemically exhaustive functionalization

Marzi, Elena; Bobbio, Carla; Cottet, Fabrice; Schlosser, Manfred, European Journal of Organic Chemistry, 2005, (10), 2116-2123

4-Chloro-5-fluoropyridine-3-carboxylic Acid Raw materials

• 4-Chloro-3-fluoropyridine

4-Chloro-5-fluoropyridine-3-carboxylic Acid Preparation Products

• 4-chloro-3-fluoro-pyridine-2-carboxylic acid (860296-21-5)
• 4-Chloro-5-fluoropyridine-3-carboxylic Acid (860296-20-4)

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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

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