Cas no 85956-22-5 (Pravastatin Lactone)

Pravastatin Lactone structure
Pravastatin Lactone structure
Product Name:Pravastatin Lactone
CAS No:85956-22-5
MF:C23H34O6
MW:406.512467861176
CID:723449
PubChem ID:9931182
Update Time:2024-10-26

Pravastatin Lactone Chemical and Physical Properties

Names and Identifiers

    • Butanoicacid, 2-methyl-,(1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenylester, (2S)-
    • Pravastatin Lactone
    • PRAVASTATIN LACTONE(RG)
    • [14C]-Pravastatin lactone
    • HMS2090H21
    • pravastatin
    • Pravastatin sodium specified impurity D [EP]
    • UNII-JBE3Z4192Q
    • R 414
    • SQ 31369
    • Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α(R*),3β,7β,8β(2S*,4S*),8aβ]]- (ZCI)
    • (+)-Pravastatin lactone
    • [(1S,3S,7S,8S,8aR)-3-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
    • PRAVASTATIN SODIUM IMPURITY, PRAVASTATIN LACTONE-[USP IMPURITY]
    • (1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-Methylbutanoate (Pravastatin Lactone)
    • SQ-31369
    • 85956-22-5
    • Pravastatin Sodium Imp. D (EP); Pravastatin Imp. D (EP); (1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl; Pravastatin Lactone; Pravastatin Sodium Impurity D; Pravastatin Impurity D
    • Pravastatin sodium impurity, pravastatin lactone- [USP]
    • PRAVASTATIN SODIUM IMPURITY, PRAVASTATIN LACTONE- [USP IMPURITY]
    • (S)-((1S,3S,7S,8S,8aR)-3-hydroxy-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate
    • (1S,3S,7S,8S,8aR)-3-Hydroxy-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8ahexahydronaphthalen-1-yl (2S)-2-methylbutanoate
    • DA-77039
    • HY-121795
    • Pravastatin sodium specified impurity D
    • AB01275516-01
    • Pravastatin sodium impurity, pravastatin lactone-[USP]
    • BDBM86706
    • Pravastatin sodium impurity, pravastatin lactone-(USP)
    • PRAVASTATIN EP IMPURITY D
    • AKOS040755957
    • DTXSID70235286
    • Butanoic acid, 2-methyl-, (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S)-
    • CHEMBL5281241
    • R-414
    • PRAVASTATIN SODIUM IMPURITY D (EP IMPURITY)
    • CS-0083314
    • Q27281422
    • SCHEMBL12122532
    • (1S,3S,7S,8S,8AR)-3-HYDROXY-8-{2-[(2R,4R)-4-HYDROXY-6-OXOOXAN-2-YL]ETHYL}-7-METHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL (2S)-2-METHYLBUTANOATE
    • PRAVASTATIN SODIUM IMPURITY, PRAVASTATIN LACTONE-(USP IMPURITY)
    • PRAVASTATIN SODIUM IMPURITY D [EP IMPURITY]
    • DTXCID70157777
    • JBE3Z4192Q
    • CHEBI:145933
    • Inchi： 1S/C23H34O6/c1-4-13(2)23(27)29-20-11-16(24)9-15-6-5-14(3)19(22(15)20)8-7-18-10-17(25)12-21(26)28-18/h5-6,9,13-14,16-20,22,24-25H,4,7-8,10-12H2,1-3H3/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1
    • InChI Key： OQARDMYXSOFTLN-PZAWKZKUSA-N
    • SMILES： O([C@H]1C[C@H](O)C=C2C=C[C@@H]([C@@H]([C@@H]12)CC[C@H]1OC(=O)C[C@H](O)C1)C)C(=O)[C@@H](C)CC

Computed Properties

  • Exact Mass: 406.23600
  • Monoisotopic Mass: 406.23553880g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 29
  • Rotatable Bond Count: 7
  • Complexity: 668
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 8
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.4
  • Topological Polar Surface Area: 93.1?2

Experimental Properties

  • Density: 1.18±0.1 g/cm3 (20 oC 760 Torr),
  • Melting Point: 140-143°C
  • Boiling Point: 590.5±50.0 °C at 760 mmHg
  • Flash Point: 199.5±23.6 °C
  • Refractive Index: 1.548
  • Solubility: Almost insoluble (0.049 g/l) (25 o C),
  • PSA: 93.06000
  • LogP: 2.92030
  • Vapor Pressure: 0.0±3.8 mmHg at 25°C

Pravastatin Lactone Security Information

Pravastatin Lactone Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
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TRC
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Pravastatin Lactone
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 $ 232.00 2023-09-06
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Pravastatin Lactone Production Method

Production Method 1

Reaction Conditions
Reference
Methyl Glyoxylate
Bhattacharya, Apurba, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, ,

Production Method 2

Reaction Conditions
1.1 Reagents: BINOL ,  (T-4)-Dibromobis(2-propanolato)titanium
2.1 -
Reference
Methyl Glyoxylate
Bhattacharya, Apurba, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, ,

Pravastatin Lactone Raw materials

Pravastatin Lactone Preparation Products

Pravastatin Lactone Related Literature

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