Cas no 857979-62-5 (2,5-Dibromothiophene-3-carboxamide)

2,5-Dibromothiophene-3-carboxamide structure
857979-62-5 structure
Product Name:2,5-Dibromothiophene-3-carboxamide
CAS No:857979-62-5
MF:C5H3Br2NOS
MW:284.956418275833
CID:1090580
PubChem ID:72183119
Update Time:2025-07-22

2,5-Dibromothiophene-3-carboxamide Chemical and Physical Properties

Names and Identifiers

    • 2,5-Dibromothiophene-3-carboxamide
    • AKOS022176203
    • Z1220054872
    • 857979-62-5
    • DTXSID10858610
    • DB-339541
    • 3-THIOPHENECARBOXAMIDE, 2,5-DIBROMO-
    • Inchi: 1S/C5H3Br2NOS/c6-3-1-2(5(8)9)4(7)10-3/h1H,(H2,8,9)
    • InChI Key: XMAYVKCRVBSBSG-UHFFFAOYSA-N
    • SMILES: BrC1=C(C(N)=O)C=C(S1)Br

Computed Properties

  • Exact Mass: 284.82816g/mol
  • Monoisotopic Mass: 282.83021g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 155
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.5
  • Topological Polar Surface Area: 71.3?2

2,5-Dibromothiophene-3-carboxamide Pricemore >>

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2,5-Dibromothiophene-3-carboxamide Related Literature

Additional information on 2,5-Dibromothiophene-3-carboxamide

Professional Introduction to 2,5-Dibromothiophene-3-carboxamide (CAS No. 857979-62-5)

2,5-Dibromothiophene-3-carboxamide, identified by the Chemical Abstracts Service Number (CAS No.) 857979-62-5, is a significant compound in the field of organic chemistry and pharmaceutical research. This heterocyclic aromatic compound features a thiophene core substituted with two bromine atoms at the 2- and 5-positions and an amide functional group at the 3-position. Its unique structural attributes make it a valuable intermediate in the synthesis of various biologically active molecules, particularly in the development of novel therapeutic agents.

The< strong>2,5-Dibromothiophene-3-carboxamide molecule's thiophene ring is a cornerstone in medicinal chemistry due to its ability to interact with biological targets in multiple ways. The presence of bromine atoms enhances its reactivity, allowing for further functionalization through cross-coupling reactions, nucleophilic substitutions, and other transformations. These properties have positioned it as a key building block in the synthesis of complex pharmacophores.

In recent years, there has been growing interest in< strong>2,5-Dibromothiophene-3-carboxamide for its potential applications in drug discovery. Researchers have leveraged its structural framework to develop compounds with antimicrobial, antiviral, and anticancer properties. For instance, studies have demonstrated its utility in constructing thiophene-based inhibitors that target specific enzymes involved in disease pathways. The bromine substituents facilitate the introduction of additional moieties, enabling fine-tuning of biological activity.

The< strong>CAS No. 857979-62-5 designation ensures unambiguous identification and traceability of this compound in research and industrial settings. This is particularly crucial in academic and pharmaceutical environments where precise chemical characterization is essential for reproducibility and regulatory compliance. The compound's stability under standard storage conditions further enhances its suitability for long-term research projects.

One of the most compelling aspects of< strong>2,5-Dibromothiophene-3-carboxamide is its role in the synthesis of advanced materials. Beyond pharmaceuticals, this compound has been explored in the development of organic electronic materials, including semiconductors and light-emitting diodes (LEDs). The conjugated system of the thiophene ring contributes to its electronic properties, making it a candidate for applications in optoelectronic devices.

The amide functionality at the 3-position of< strong>2,5-Dibromothiophene-3-carboxamide introduces additional reactivity that can be exploited for bioconjugation purposes. This has opened up avenues for creating prodrugs or targeted drug delivery systems where the amide bond can be selectively cleaved under specific physiological conditions. Such innovations are critical for improving therapeutic efficacy while minimizing side effects.

In conclusion, 2,5-Dibromothiophene-3-carboxamide (CAS No. 857979-62-5) represents a versatile and multifaceted compound with broad applications across chemistry and medicine. Its unique structural features make it an indispensable tool for synthetic chemists and pharmacologists alike. As research continues to uncover new methodologies and applications, this compound is poised to remain at the forefront of chemical innovation.

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