Cas no 857091-32-8 (Gefitinib-d)

Gefitinib-d structure

Product Name:Gefitinib-d

CAS No:857091-32-8

MF:C₂₂H₂₄ClFN₄O₃

MW:454.951661109924

MDL:MFCD30748179

CID:1076058

PubChem ID:49849312

Update Time:2024-10-26

Gefitinib-d Chemical and Physical Properties

Names and Identifiers

- [2H8]-Gefitinib
- Gefitinib D8
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine
- Gefitinib-d8
- Gefitinib-d
- AKOS040733242
- G16049
- DTXSID60678648
- MS-28290
- 857091-32-8
- DA-53533
- HY-50895S
- CS-0019810
- 1ST159193D8
- N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-{3-[(~2~H_8_)morpholin-4-yl]propoxy}quinazolin-4-amine
- ZD1839 D8
- MDL： MFCD30748179
- Inchi： 1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)/i6D2,7D2,9D2,10D2
- InChI Key： XGALLCVXEZPNRQ-IHGLQNJRSA-N
- SMILES： N(C1C=CC(F)=C(Cl)C=1)C1=NC=NC2=CC(=C(C=C12)OCCCN1C([2H])([2H])C([2H])([2H])OC([2H])([2H])C1([2H])[2H])OC

Computed Properties

Exact Mass: 454.20200
Monoisotopic Mass: 454.2023105g/mol
Isotope Atom Count: 8
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 8
Heavy Atom Count: 31
Rotatable Bond Count: 8
Complexity: 545
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 4.1
Topological Polar Surface Area: 68.7?2

Experimental Properties

PSA: 68.74000
LogP: 4.28650

Gefitinib-d Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
ChemScence	CS-0019810-5mg	Gefitinib-d8	857091-32-8	98.42%	5mg	$550.0	2022-04-26
MedChemExpress	HY-50895S-5mg	Gefitinib-d	857091-32-8	98.42%	5mg	￥18200	2023-08-31
Key Organics Ltd	MS-28290-1mg	Gefitinib-d8	857091-32-8	>97%	1mg	￡1051.43	2025-02-09
A2B Chem LLC	BA56248-1mg	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine	857091-32-8	98%	1mg	$685.00	2024-04-19
A2B Chem LLC	BA56248-5mg	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine	857091-32-8	98%	5mg	$1855.00	2024-04-19
eNovation Chemicals LLC	D622629-5mg	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine	857091-32-8	98%	5mg	$2000	2025-02-22
eNovation Chemicals LLC	D622629-100mg	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine	857091-32-8	98%	100mg	$6850	2025-02-22
eNovation Chemicals LLC	D622629-5mg	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine	857091-32-8	98%	5mg	$2000	2024-08-03
MedChemExpress	HY-50895S-1mg	Gefitinib-d	857091-32-8	98.42%	1mg	￥1900	2025-04-15
eNovation Chemicals LLC	D622629-100mg	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine	857091-32-8	98%	100mg	$6850	2024-08-03

Gefitinib-d Production Method

Production Method 1

184475-71-6

342611-02-3

857091-32-8

Reaction Conditions

1.1 Solvents: Toluene
1.2 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 80 °C
1.3 Reagents: Hydrochloric acid Solvents: Diethyl ether

Reference

Synthesis of isotopomers of gefitinib

Bergin, J. A.; et al, Synthesis and Applications of Isotopically Labelled Compounds, 2004, 301, 301-304

Gefitinib-d Raw materials

Gefitinib-d Preparation Products

Gefitinib-d (857091-32-8)

Gefitinib-d Related Literature

1. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies

Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
2. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?

Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
3. Fe3O4/Au/Fe3O4 nanoflowers exhibiting tunable saturation magnetization and enhanced bioconjugation

Feng Shi,Kunping Yan,Mingli Peng,Xiao Cheng,Yanling Luo,Xuemei Chen,V. A. L. Roy,Zuankai Wang Nanoscale, 2012,4, 747-751
4. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?

Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
5. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents

Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090

857091-32-8 (Gefitinib-d) Related Products

Recommended suppliers

Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.

Gold Member

Audited Supplier

CN Supplier

Reagent

Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.

PRIBOLAB PTE.LTD

Gold Member

Audited Supplier

CN Supplier

Reagent

鉅瀾化工科技(青島)有限公司

Gold Member

Audited Supplier

CN Supplier

Bulk

Shandong Jing Kun Chemical Co.,Ltd.

Gold Member

Audited Supplier

CN Supplier

Bulk

Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.

Gold Member

Audited Supplier

CN Supplier

Reagent

Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.

国产一区二区制服丝袜_一级特黄高清完整大片_欧美.亚洲.日韩.另类.av_黄又色又污又爽又高潮动态图_91夫妻视频电影观看_在线手机亚洲中文字幕_国产中文字幕不卡在线_国产乱妇乱子在线播视频播放网站_gogo裸体艺术中国日本

Cas no 857091-32-8 (Gefitinib-d)

Gefitinib-d Chemical and Physical Properties

Names and Identifiers

Computed Properties

Experimental Properties

Gefitinib-d Pricemore >>

Gefitinib-d Production Method

Production Method 1

Gefitinib-d Raw materials

Gefitinib-d Preparation Products

Gefitinib-d Related Literature

857091-32-8 (Gefitinib-d) Related Products