Cas no 857070-66-7 (1H-Benzimidazole-6-methanol,2-chloro-)

1H-Benzimidazole-6-methanol,2-chloro- structure
857070-66-7 structure
Product Name:1H-Benzimidazole-6-methanol,2-chloro-
CAS No:857070-66-7
MF:C8H7ClN2O
MW:182.60698056221
CID:717659
PubChem ID:24801541
Update Time:2024-10-26

1H-Benzimidazole-6-methanol,2-chloro- Chemical and Physical Properties

Names and Identifiers

    • 1H-Benzimidazole-6-methanol,2-chloro-
    • (2-CHLORO-1H-BENZO[D]IMIDAZOL-6-YL)METHANOL
    • (2-chloro-3H-benzimidazol-5-yl)methanol
    • 2-CHLORO-1H-BENZIMIDAZOLE-6-METHANOL
    • 1H-Benzimidazole-5-methanol, 2-chloro- (9CI)
    • 2-Chloro-1H-benzimidazole-6-methanol (ACI)
    • (2-Chloro-1H-1,3-benzodiazol-5-yl)methanol
    • (2-Chloro-1H-1,3-benzodiazol-6-yl)methanol
    • SCHEMBL6467818
    • AKOS006307600
    • 857070-66-7
    • DTXSID00647358
    • XH0019
    • D83878
    • (2-Chloro-1H-benzimidazol-6-yl)methanol
    • AKOS027379793
    • BS-18186
    • Inchi： 1S/C8H7ClN2O/c9-8-10-6-2-1-5(4-12)3-7(6)11-8/h1-3,12H,4H2,(H,10,11)
    • InChI Key： VIZZPVUEIUQVQX-UHFFFAOYSA-N
    • SMILES： ClC1NC2C(=CC(CO)=CC=2)N=1

Computed Properties

  • Exact Mass: 182.0246905g/mol
  • Monoisotopic Mass: 182.0246905g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 167
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.2
  • Topological Polar Surface Area: 48.9?2

Experimental Properties

  • PSA: 48.91000
  • LogP: 1.70860

1H-Benzimidazole-6-methanol,2-chloro- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-AK605-50mg
1H-Benzimidazole-6-methanol,2-chloro-
 857070-66-7 97%
50mg
 598.0CNY 2021-07-09
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-AK605-200mg
1H-Benzimidazole-6-methanol,2-chloro-
 857070-66-7 97%
200mg
 1495.0CNY 2021-07-09
SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd.
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(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 97%
100mg
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SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd.
BD72583-250mg
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 97%
250mg
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SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd.
BD72583-1g
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 97%
1g
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Chemenu
CM526464-100mg
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 97%
100mg
 $92 2023-02-01
Chemenu
CM526464-250mg
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 97%
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Chemenu
CM526464-1g
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 97%
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eNovation Chemicals LLC
Y1227402-5g
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 95%
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 $2000 2024-06-03
Key Organics Ltd
BS-18186-100MG
(2-Chloro-1H-benzo[d]imidazol-6-yl)methanol
 857070-66-7 >97%
100mg
 ￡157.00 2025-02-08

1H-Benzimidazole-6-methanol,2-chloro- Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Phosphorus oxychloride ;  100 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  6 h, 120 °C
2.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  3 h, 5 °C
Reference
Selection of a Respiratory Syncytial Virus Fusion Inhibitor Clinical Candidate. 2. Discovery of a Morpholinopropylaminobenzimidazole Derivative (TMC353121)
Bonfanti, Jean-Francois; et al, Journal of Medicinal Chemistry, 2008, 51(4), 875-896

Production Method 2

Reaction Conditions
1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  3 h, 5 °C
Reference
Selection of a Respiratory Syncytial Virus Fusion Inhibitor Clinical Candidate. 2. Discovery of a Morpholinopropylaminobenzimidazole Derivative (TMC353121)
Bonfanti, Jean-Francois; et al, Journal of Medicinal Chemistry, 2008, 51(4), 875-896

Production Method 3

Reaction Conditions
1.1 Solvents: Xylene ;  12 h, reflux
2.1 Reagents: Phosphorus oxychloride ;  100 °C
2.2 Reagents: Hydrochloric acid Solvents: Water ;  6 h, 120 °C
3.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  3 h, 5 °C
Reference
Selection of a Respiratory Syncytial Virus Fusion Inhibitor Clinical Candidate. 2. Discovery of a Morpholinopropylaminobenzimidazole Derivative (TMC353121)
Bonfanti, Jean-Francois; et al, Journal of Medicinal Chemistry, 2008, 51(4), 875-896

1H-Benzimidazole-6-methanol,2-chloro- Raw materials

1H-Benzimidazole-6-methanol,2-chloro- Preparation Products

1H-Benzimidazole-6-methanol,2-chloro- Related Literature

857070-66-7 (1H-Benzimidazole-6-methanol,2-chloro-) Related Products

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