Production Method 1

811-98-3

88-99-3

85448-30-2

Reaction Conditions

1.1 Reagents: Sulfuric acid Solvents: Methanol-d4 ,  Water ;  90 min, 70 °C

Reference

Variations in GC-MS Response Between Analytes and Deuterated Analogs

Alzweiri, Muhammed; et al, Chromatographia, 2015, 78(3-4), 251-258

Dimethyl phthalate-d Raw materials

• Methanol-d4, 99.8%(High purity)
• Phthalic acid

Dimethyl phthalate-d Preparation Products

• Dimethyl phthalate-d (85448-30-2)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acid esters
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acid esters

Dimethyl phthalate-d (CAS No. 85448-30-2): A Comprehensive Guide to Its Properties and Applications

Dimethyl phthalate-d (CAS No. 85448-30-2), also known as DMP-d, is a deuterated analog of dimethyl phthalate (DMP). This compound is widely used in analytical chemistry, environmental science, and pharmaceutical research due to its unique isotopic labeling. The deuterium substitution in DMP-d enhances its utility as an internal standard in mass spectrometry and nuclear magnetic resonance (NMR) studies, ensuring accurate quantification and traceability in complex matrices.

The growing demand for isotopically labeled compounds like Dimethyl phthalate-d is driven by advancements in precision medicine and environmental monitoring. Researchers increasingly rely on DMP-d to study metabolic pathways, pollutant degradation, and drug metabolism. Its stability and compatibility with high-resolution analytical techniques make it indispensable in modern laboratories.

One of the key advantages of Dimethyl phthalate-d (CAS No. 85448-30-2) is its role in green chemistry. As industries shift toward sustainable practices, deuterated compounds are gaining traction for reducing chemical waste and improving process efficiency. DMP-d is particularly valuable in LC-MS and GC-MS workflows, where it minimizes interference and enhances signal clarity.

In the context of consumer safety, Dimethyl phthalate-d is often discussed in relation to phthalate exposure and human biomonitoring. Public interest in endocrine-disrupting chemicals (EDCs) has surged, with many seeking information on how deuterated standards like DMP-d help detect and quantify such compounds in biological samples. This aligns with global efforts to assess chemical safety and regulatory compliance.

From a technical perspective, CAS No. 85448-30-2 is characterized by high chemical purity and isotopic enrichment, typically exceeding 98%. These specifications ensure reproducibility in research applications, whether in forensic toxicology or material science. The compound’s compatibility with aqueous and organic solvents further broadens its utility.

Looking ahead, the applications of Dimethyl phthalate-d are expected to expand into emerging fields such as microplastics research and personalized healthcare. As analytical techniques evolve, the demand for high-performance isotopic standards will continue to rise, solidifying DMP-d as a cornerstone of scientific innovation.

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