Production Method 1

4885-02-3

85231-15-8

Reaction Conditions

1.1 Reagents: Aluminum chloride Solvents: Dichloromethane ;  rt → 0 °C
1.2 0 °C; 2 h, -5 - 0 °C
1.3 Reagents: Water ;  0 °C

Reference

A transition metal-free approach to a regioselective total synthesis of the natural product derivative 6-methylellipticine, a potent anticancer agent

Lin, Song-Bo; Wang, Wan-Wan; Meng, Jin-Peng; Li, Xi-Wang; Wu, Jun; et al, Tetrahedron Letters, 2019, 60(51),

Production Method 2

85231-15-8

Reaction Conditions

Reference

Arenecarbaldehydes: synthesis by formylation of arene-hydrogen bonds

Schall, A.; Reiser, O., Science of Synthesis, 2007, 25, 605-653

Production Method 3

85231-15-8

1666-04-2

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Water

Reference

2,2'-Bifurylidene-5,5'-diones, coumarins, 3a,7a-dihydro-1H-inden-1-ones, and 5H-furo[3,2-b]pyran-5-ones from propyne and carbon monoxide

Rautenstrauch, Valentin; Megard, Patrick; Gamper, Betty; Bourdin, Bernadette; Walther, Eric; et al, Helvetica Chimica Acta, 1989, 72(4), 811-24

Production Method 4

85231-15-8

1666-04-2

Reaction Conditions

1.1 Solvents: Chloroform ,  Water

Reference

The Reimer-Tiemann reaction

Wynberg, Hans; Meijer, Egbert W., Organic Reactions (Hoboken, 1982, 28,

Production Method 5

4885-02-3

85231-15-8

1666-04-2

Reaction Conditions

1.1 Reagents: Aluminum chloride Solvents: Dichloromethane ;  -5 °C; 5 min, 0 °C
1.2 Solvents: Water ;  cooled

Reference

An expedient synthesis of ellipticine via Suzuki-Miyaura coupling

Konakahara, Takeo; Kiran, Y. B.; Okuno, Yuri; Ikeda, Reiko; Sakai, Norio, Tetrahedron Letters, 2010, 51(17), 2335-2338

4-Hydroxy-2,5-dimethylbenzaldehyde Raw materials

• 1,1-Dichlorodimethyl ether

4-Hydroxy-2,5-dimethylbenzaldehyde Preparation Products

• 4-Hydroxy-2,5-dimethylbenzaldehyde (85231-15-8)
• 2-Hydroxy-3,6-dimethylbenzaldehyde (1666-04-2)

• 1. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
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• 5. Distinct impact of glycation towards the aggregation and toxicity of murine and human amyloid-β?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Xylenols
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Xylenes Xylenols

• 88122-12-7(Benzaldehyde, 3,4-dihydroxy-2-methyl-)
• 53711-21-0(2,5-dihydroxy-3,4,6-trimethylbenzaldehyde)
• 58380-40-8(Benzaldehyde, 4-hydroxy-2,3-dimethyl-)
• 31404-85-0(Benzaldehyde,3,6-dihydroxy-2,4-dimethyl-)
• 1666-04-2(2-Hydroxy-3,6-dimethylbenzaldehyde)
• 179554-20-2(Benzaldehyde,3-hydroxy-2,6-dimethyl-)
• 487-69-4(2,4-Dihydroxy-6-methylbenzaldehyde)
• 73289-89-1(1,2-Benzenedicarboxaldehyde, 3-hydroxy-)
• 2990-31-0(Benzaldehyde,4,6-dihydroxy-2,3-dimethyl-)
• 52643-54-6(3,6-dihydroxy-4,5-dimethylbenzene-1,2-dicarbaldehyde)