Cas no 852054-42-3 (7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde)

7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde is a brominated heterocyclic aldehyde with a fused thienodioxine core, offering versatile reactivity for synthetic applications. Its structure combines an electron-rich dioxine moiety with an aldehyde functional group, making it a valuable intermediate in organic synthesis, particularly for constructing complex heterocycles or conjugated systems. The bromine substituent enhances its utility in cross-coupling reactions, such as Suzuki or Sonogashira couplings, enabling further derivatization. This compound is particularly useful in materials science and pharmaceutical research, where its unique scaffold can contribute to the development of functionalized polymers or bioactive molecules. Its stability and well-defined reactivity profile make it a reliable building block for advanced chemical synthesis.
7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde structure
852054-42-3 structure
Product Name:7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde
CAS No:852054-42-3
MF:C7H5BrO3S
MW:249.081800222397
MDL:MFCD08690306
CID:719696
PubChem ID:11391008
Update Time:2025-10-07

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Chemical and Physical Properties

Names and Identifiers

    • 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
    • 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxaldehyde
    • 5-bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-7-carbaldehyde
    • Thieno[3,4-b]-1,4-dioxin-5-carboxaldehyde,7-bromo-2,3-dihydro-
    • 7-BROMO-2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXINE-5-CARBOXALDEHYDE 97
    • 7-bromo-2H,3H-thieno[3,4-b][1,4]dioxine-5-carbaldehyde
    • BCP17569
    • OR8641
    • SBB100517
    • CB0162
    • FCH1327030
    • AX8110336
    • AB0027019
    • ST24029892
    • W8796
    • 2,3-Dihydro-7-bromoth
    • ST240
    • 7-Bromo-2,3-dihydrothieno[3,4-b]-1,4-dioxin-5-carboxaldehyde (ACI)
    • 7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde, AldrichCPR
    • DS-17037
    • MFCD08690306
    • 7-Bromo-2 pound not3-dihydrothieno[3 pound not4-b][1 pound not4]dioxine-5-carbaldehyde
    • SCHEMBL14852718
    • EN300-1718462
    • 5-bromo-3,4-ethylenedioxythiophene-2-carbaldehyde
    • AKOS015920293
    • Z1269175252
    • DTXSID40464445
    • CS-0103681
    • B5396
    • 852054-42-3
    • C7H5BrO3S
    • DB-076277
    • 7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde
    • MDL： MFCD08690306
    • Inchi： 1S/C7H5BrO3S/c8-7-6-5(4(3-9)12-7)10-1-2-11-6/h3H,1-2H2
    • InChI Key： YEKBJVHBVICUOZ-UHFFFAOYSA-N
    • SMILES： O=CC1=C2C(OCCO2)=C(Br)S1

Computed Properties

  • Exact Mass: 247.91400
  • Monoisotopic Mass: 247.91428g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 190
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 63.8
  • XLogP3: 2.1

Experimental Properties

  • Density: 1.835±0.06 g/cm3 (20 oC 760 Torr)
  • Melting Point: 147.0 to 152.0 deg-C
  • Boiling Point: 351.5°C at 760 mmHg
  • Flash Point: 166.4°C
  • Refractive Index: 1.656
  • PSA: 63.77000
  • LogP: 2.09430

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Security Information

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Customs Data

  • HS CODE：2934999090
  • Customs Data：

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
093334-250mg
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3 95%
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Fluorochem
093334-1g
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Fluorochem
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 852054-42-3 95%
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Fluorochem
093334-10g
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Alichem
A169007800-1g
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3 95%
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Alichem
A169007800-5g
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3 95%
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Alichem
A169007800-10g
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3 95%
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TRC
B683190-25mg
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3
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 $ 64.00 2023-04-18
TRC
B683190-50mg
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3
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 $ 75.00 2023-04-18
TRC
B683190-100mg
7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
 852054-42-3
100mg
 $ 110.00 2023-04-18

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Acetonitrile ;  0 °C; 60 h, rt
Reference
Efficiency enhancement of ruthenium-based DSSCs employing A-p-D-p-A organic Co-sensitizers
Abdellah, Islam M.; El-Shafei, Ahmed, RSC Advances, 2020, 10(47), 27940-27953

Production Method 2

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Dimethylformamide ;  overnight, rt
Reference
Photocatalysts for H2 generation from starburst triphenylamine/carbazole donor-based metal-free dyes and porous anatase TiO2 cube
Huang, Jian-Feng; Lei, Yang; Xiao, Li-Min; Chen, Xin-Lun; Zhong, Yu-Hui; et al, ChemSusChem, 2020, 13(5), 1037-1043

Production Method 3

Reaction Conditions
1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran ;  10 min, -78 °C
1.2 -78 °C → rt; overnight, rt
1.3 Reagents: Hydrochloric acid Solvents: Water
1.4 Reagents: N-Bromosuccinimide Solvents: Dimethylformamide ;  2 h, rt
Reference
Simple organic molecules bearing a 3,4-ethylenedioxythiophene linker for efficient dye-sensitized solar cells
Liu, Wei-Hsin; Wu, I-Che; Lai, Chin-Hung; Lai, Cheng-Hsuan; Chou, Pi-Tai; et al, Chemical Communications (Cambridge, 2008, (41), 5152-5154

Production Method 4

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Acetic acid ,  Tetrahydrofuran ,  Water ;  0 °C; 17 h, rt
Reference
Preparative Fluorous Mixture Synthesis of Diazonium-Functionalized Oligo(phenylene vinylene)s
Jian, Huahua; Tour, James M., Journal of Organic Chemistry, 2005, 70(9), 3396-3424

Production Method 5

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Dimethylformamide ;  25 °C; 60 h, 25 °C
Reference
Electrochemical impedance parameters elucidate performance of carbazole-triphenylamine-ethylenedioxythiophene-based molecules in dye-sensitized solar cells
Yang, Chien-Hsin; Sun, Yu-Kuang; Chuang, Yao-Yuan; Wang, Tzong-Liu; Shieh, Yeong-Tarng; et al, Electrochimica Acta, 2012, 69, 256-267

Production Method 6

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Chloroform ;  0 °C; overnight, rt
Reference
Energy levels, charge injection, charge recombination and dye regeneration dynamics for donor-acceptor π-conjugated organic dyes in mesoscopic TiO2 sensitized solar cells
Planells, Miquel; Pelleja, Laia; Clifford, John N.; Pastore, Mariachiara; De Angelis, Filippo; et al, Energy & Environmental Science, 2011, 4(5), 1820-1829

Production Method 7

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Acrylonitrile ;  0 °C; 60 h, rt
Reference
A new series of EDOT based co-sensitizers for enhanced efficiency of cocktail DSSC: a comparative study of two different anchoring groups
Koyyada, Ganesh ; Chitumalla, Ramesh Kumar; Thogiti, Suresh; Kim, Jae Hong; Jang, Joonkyung ; et al, Molecules, 2019, 24(19),

Production Method 8

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Acetonitrile ;  rt → 0 °C; 60 h, rt
Reference
Thiophene backbone amide linkers, a new class of easily prepared and highly acid-labile linkers for solid-phase synthesis
Jessing, Mikkel; Brandt, Malene; Jensen, Knud J.; Christensen, Jorn B.; Boas, Ulrik, Journal of Organic Chemistry, 2006, 71(18), 6734-6741

Production Method 9

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Tetrahydrofuran ;  3 d, rt
Reference
Synthesis and Optical Properties of New Chalcones Containing a 3,4-Ethylenedioxythiophene Fragment
Ignashevich, A. N.; Shavrina, T. V.; Shklyaeva, E. V.; Abashev, G. G., Russian Journal of Organic Chemistry, 2020, 56(11), 1920-1928

Production Method 10

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Acetic acid ,  Tetrahydrofuran ;  cooled; 17 h, rt
Reference
Organic sensitizers with bridged triphenylamine donor units for efficient dye-sensitized solar cells
Cai, Liping; Tsao, Hoi Nok; Zhang, Wei; Wang, Long; Xue, Zhaosheng; et al, Advanced Energy Materials, 2013, 3(2), 200-205

Production Method 11

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Chloroform ;  rt; 45 min, rt
1.2 Reagents: Sodium sulfite Solvents: Water ;  rt
Reference
Green Solvent-Processed Hemi-Isoindigo Polymers for Stable Temperature Sensors
Ngai, Jenner H. L.; Polena, John; Afzal, Daniel; Gao, Xiguang; Kapadia, Mihir; et al, Advanced Functional Materials, 2022, 32(17),

Production Method 12

Reaction Conditions
1.1 Reagents: Sodium bicarbonate ,  Bromine Solvents: Chloroform ;  4 h, reflux
Reference
Synthesis of π-Conjugated 2,2:6',2''-Terpyridine-Substituted Oligomers Based on 3,4-Ethylenedioxythiophene
Fillaud, Laure; Trippe-Allard, Gaelle; Lacroix, Jean Christophe, Organic Letters, 2013, 15(5), 1028-1031

Production Method 13

Reaction Conditions
1.1 Reagents: N-Bromosuccinimide Solvents: Dimethylformamide ;  rt; 4 h, 20 °C; cooled
Reference
Spectral and Photophysical Characterization of Donor-π-Acceptor Arylthienyl- and Bithienyl-Benzothiazole Derivatives in Solution and Solid State
Pina, Joao; Seixas de Melo, J. Sergio; Burrows, Hugh D.; Batista, Rosa M. F.; Costa, Susana P. G.; et al, Journal of Physical Chemistry A, 2007, 111(35), 8574-8578

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Raw materials

7-Bromo-2,3-dihydrothieno3,4-b1,4dioxine-5-carbaldehyde Preparation Products

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SunaTech Inc.
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(CAS:852054-42-3)7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
Order Number:IN1910
Stock Status:in Stock
Quantity:1g;5g;10g
Purity:98%
Pricing Information Last Updated:Friday, 25 July 2025 14:34
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SunaTech Inc.
(CAS:852054-42-3)7-Bromo-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde
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Purity:98%
Quantity:1g;5g;10g
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