Cas no 851886-92-5 (7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one)

7-Amino-1,3-dihydro-1-methyl-2H-benzimidazol-2-one is a benzimidazole derivative with a molecular formula of C8H9N3O. This heterocyclic compound features a reactive amino group at the 7-position, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Its rigid benzimidazole core enhances stability, while the methyl substitution at the 1-position influences steric and electronic properties. The compound is particularly useful in the development of bioactive molecules, including kinase inhibitors and antimicrobial agents, due to its ability to participate in hydrogen bonding and π-stacking interactions. High purity grades are available for research applications, ensuring reproducibility in synthetic pathways. Proper handling under inert conditions is recommended due to potential sensitivity to oxidation.
7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one structure
851886-92-5 structure
Product Name:7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one
CAS No:851886-92-5
MF:C8H9N3O
MW:163.176561117172
CID:1119011
PubChem ID:59635419
Update Time:2025-05-19

7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one Chemical and Physical Properties

Names and Identifiers

    • 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one
    • 851886-92-5
    • 7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
    • 7-amino-1-methyl-1,3-dihydro-2H-benzimidazol-2-one
    • EN300-7849699
    • 7-amino-1-methyl-1,3-dihydrobenzimidazol-2-one
    • 7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
    • SCHEMBL2082442
    • 7-amino-1-methyl-1,3-dihydro-2H-benzoimidazol-2-one
    • HURLDMSOLJJDGK-UHFFFAOYSA-N
    • G75043
    • Inchi: 1S/C8H9N3O/c1-11-7-5(9)3-2-4-6(7)10-8(11)12/h2-4H,9H2,1H3,(H,10,12)
    • InChI Key: HURLDMSOLJJDGK-UHFFFAOYSA-N
    • SMILES: O=C1NC2C=CC=C(C=2N1C)N

Computed Properties

  • Exact Mass: 163.074561919g/mol
  • Monoisotopic Mass: 163.074561919g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 207
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 58.4?2

7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Enamine
EN300-7849699-0.05g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
0.05g
$827.0 2025-03-21
Enamine
EN300-7849699-0.1g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
0.1g
$867.0 2025-03-21
Enamine
EN300-7849699-0.25g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
0.25g
$906.0 2025-03-21
Enamine
EN300-7849699-0.5g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
0.5g
$946.0 2025-03-21
Enamine
EN300-7849699-1.0g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
1.0g
$986.0 2025-03-21
Enamine
EN300-7849699-2.5g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
2.5g
$1931.0 2025-03-21
Enamine
EN300-7849699-5.0g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
5.0g
$2858.0 2025-03-21
Enamine
EN300-7849699-10.0g
7-amino-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one
851886-92-5 95.0%
10.0g
$4236.0 2025-03-21
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1637799-100mg
7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
851886-92-5 98%
100mg
¥2457.00 2024-07-28
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1637799-250mg
7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
851886-92-5 98%
250mg
¥4725.00 2024-07-28

Additional information on 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one

Comprehensive Overview of 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one (CAS No. 851886-92-5)

7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one (CAS No. 851886-92-5) is a specialized organic compound belonging to the benzimidazole class, which has garnered significant attention in pharmaceutical and biochemical research. This compound, characterized by its amino and methyl functional groups, serves as a critical intermediate in the synthesis of various bioactive molecules. Its unique structure makes it a valuable candidate for applications in drug discovery, particularly in targeting enzymes and receptors involved in metabolic pathways.

The growing interest in benzimidazole derivatives stems from their diverse pharmacological properties, including antimicrobial, antiviral, and anticancer activities. Researchers are increasingly exploring 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one for its potential role in developing novel therapeutics. For instance, its structural similarity to purine bases allows it to interact with DNA and RNA, making it a promising scaffold for designing small-molecule inhibitors. This aligns with current trends in precision medicine, where targeted therapies are in high demand.

From a synthetic chemistry perspective, the compound’s CAS No. 851886-92-5 is often referenced in patents and academic publications detailing innovative synthetic routes. Its amino group provides a reactive site for further functionalization, enabling the creation of libraries of derivatives for high-throughput screening. This is particularly relevant in the context of AI-driven drug discovery, where computational models predict the bioactivity of such compounds before laboratory validation. As a result, 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one is frequently discussed in forums focusing on cheminformatics and molecular docking studies.

Another area of interest is the compound’s potential role in green chemistry. With sustainability becoming a priority, researchers are investigating eco-friendly synthesis methods for benzimidazole derivatives. 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one can be synthesized using catalytic processes that minimize waste and reduce energy consumption, addressing the demand for sustainable pharmaceuticals. This aligns with global initiatives like the UN’s Sustainable Development Goals (SDGs), particularly Goal 12 (Responsible Consumption and Production).

In analytical chemistry, the compound’s purity and stability are critical for reproducible results. Advanced techniques such as HPLC and LC-MS are employed to characterize CAS No. 851886-92-5, ensuring compliance with regulatory standards. This is especially important for researchers sourcing the compound for preclinical studies, where consistency is paramount. Frequently asked questions (FAQs) in online forums often revolve around its solubility, storage conditions, and compatibility with common reagents.

Beyond pharmaceuticals, 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one has potential applications in material science. Its conjugated system and heterocyclic core make it a candidate for developing organic semiconductors or fluorescent probes. This versatility underscores its relevance in interdisciplinary research, bridging gaps between chemistry, biology, and engineering.

In summary, 7-amino-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one (CAS No. 851886-92-5) is a multifaceted compound with broad applicability in drug development, sustainable chemistry, and advanced materials. Its integration into cutting-edge research areas like AI-augmented discovery and green synthesis highlights its enduring significance. As scientific communities continue to explore its properties, this compound is poised to remain a focal point in innovation-driven industries.

Recommended suppliers
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Inner Mongolia Xinhong Biological Technology Co., Ltd
SunaTech Inc.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
SunaTech Inc.
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.