Cas no 851211-74-0 (1H-Indole-6-carbohydrazide)

1H-Indole-6-carbohydrazide structure
1H-Indole-6-carbohydrazide structure
Product Name:1H-Indole-6-carbohydrazide
CAS No:851211-74-0
MF:C9H9N3O
MW:175.187261343002
MDL:MFCD11977799
CID:717026
PubChem ID:21811249
Update Time:2024-10-26

1H-Indole-6-carbohydrazide Chemical and Physical Properties

Names and Identifiers

    • 1H-Indole-6-carboxylic acid hydrazide
    • 1H-INDOLE-6-CARBOHYDRAZIDE
    • 1H-Indole-6-carboxylic acid, hydrazide
    • IUMFFGBZQDGHEM-UHFFFAOYSA-N
    • 3165AC
    • 1H-Indole-6-carboxylic acid,hydrazide
    • 1H-Indole-6-carboxylicacid, hydrazide
    • AK104010
    • 1H-Indole-6-carboxylic hydrazide
    • AS-58724
    • 851211-74-0
    • EN300-4257360
    • CS-0149899
    • SCHEMBL232249
    • DTXSID20618282
    • BJB21174
    • F17946
    • AKOS009469097
    • 1H-Indole-6-carbohydrazide
    • MDL: MFCD11977799
    • Inchi: 1S/C9H9N3O/c10-12-9(13)7-2-1-6-3-4-11-8(6)5-7/h1-5,11H,10H2,(H,12,13)
    • InChI Key: IUMFFGBZQDGHEM-UHFFFAOYSA-N
    • SMILES: O=C(C1C=C2C(C=CN2)=CC=1)NN

Computed Properties

  • Exact Mass: 175.074561919g/mol
  • Monoisotopic Mass: 175.074561919g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 207
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.2
  • Topological Polar Surface Area: 70.9

1H-Indole-6-carbohydrazide Pricemore >>

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1H-Indole-6-carbohydrazide Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Water ;  5 - 8 min, reflux
Reference
Microwave-assisted synthesis of new hydrazone compounds with two indole rings with antibacterial activities
Ye, Ying; Suo, You-rui; Yang, Fang; Yang, Yong-jing; Han, Li-juan, Huaxue Shiji, 2015, 37(7), 585-589

Production Method 2

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) ;  5 - 8 min, rt
Reference
Microwave-assisted synthesis and molecular recognition properties of novel indole acylhydrazone receptors
Ye, Ying; Suo, Yourui; Yang, Fang; Yang, Yongjing; Han, Lijuan, Journal of Chemical Research, 2015, 39(5), 296-299

Production Method 3

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) ;  10 min
Reference
Synthesis and antibacterial activities of novel 6-substituted indole derivatives containing 1,2,4-triazole Schiff base units promoted by microwave irradiation
Liu, Xing-li; Shi, Zhi-chuan; Zhao, Zhi-gang; Wang, Xiao-hong, Xinan Minzu Daxue Xuebao, 2014, 40(1), 44-48

Production Method 4

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Water ;  10 min, heated; cooled
Reference
Microwave-assisted synthesis of oxadiazoline derivatives containing indole structure and their antibacterial activities
Zhao, Zhigang; Liu, Xingli; Chen, Yu; Li, Hui; Shi, Zhichuan, Youji Huaxue, 2010, 30(12), 1949-1954

Production Method 5

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Water ;  10 min, heated
Reference
Synthesis and characterization of 3-acetyl-2-aryl-5-(6-indole)-1,3,4-oxadiazoline derivatives under microwave irradiation conditions
Ye, Ying; Zhao, Zhigang; Li, Qinghan; Chen, Yu, Huaxue Yanjiu Yu Yingyong, 2009, 21(9), 1340-1343

Production Method 6

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Water ;  10 min, heated
Reference
Microwave-assisted synthesis of indole-6-acylhydrazone and their antibacterial activities
Ye, Ying; Zhao, Zhigang; Liu, Xingli; Li, Qinghan, Youji Huaxue, 2009, 29(6), 993-997

Production Method 7

Reaction Conditions
1.1 Reagents: Hydrazine Solvents: Methanol ;  15 min
Reference
Microwave-assisted synthesis and characterization of indol-6-ylcarbohydrazones
Li, Qinghan; Zhao, Zhigang, Huaxue Yanjiu Yu Yingyong, 2008, 20(8), 988-991

Production Method 8

Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1)
Reference
Synthesis and antibacterial activities of 6-substituted indole derivatives containing oxadiazole and sulfide units
Liu, Xing-li; Shi, Zhi-chuan; Zhao, Zhi-gang; Wang, Zhi-jing; Ye, Ying, Xinan Minzu Daxue Xuebao, 2013, 39(6), 877-880

1H-Indole-6-carbohydrazide Raw materials

1H-Indole-6-carbohydrazide Preparation Products

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