Cas no 850881-70-8 (Coumoxystrobin)

Coumoxystrobin is a novel strobilurin fungicide that combines the active moiety of coumoxystrobin with a methoxyacrylate group, exhibiting broad-spectrum activity against a wide range of fungal pathogens. It functions by inhibiting mitochondrial respiration through binding to the Qo site of cytochrome b, effectively disrupting energy production in fungal cells. This compound demonstrates excellent preventive and curative properties, particularly against diseases such as powdery mildew, rust, and leaf spot in crops. Its systemic and translaminar movement ensures uniform distribution within plant tissues, enhancing protective efficacy. Coumoxystrobin also exhibits low mammalian toxicity and favorable environmental profiles, making it suitable for integrated pest management (IPM) programs. Its stability under varying environmental conditions further supports its reliability in field applications.
Coumoxystrobin structure
Coumoxystrobin structure
Product Name:Coumoxystrobin
CAS No:850881-70-8
MF:C26H28O6
MW:436.496928215027
CID:2851882
PubChem ID:45380432
Update Time:2025-11-01

Coumoxystrobin Chemical and Physical Properties

Names and Identifiers

    • methyl (E)-2-[2-[(3-butyl-4-methyl-2-oxochromen-7-yl)oxymethyl]phenyl]-3-methoxyprop-2-enoate
    • Coumoxystrobin
    • Coumoxystrobine
    • 521R9X5RXY
    • Dingxiangjunzhi
    • Methyl (alphaE)-2-(((3-butyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy)methyl)-alpha-(methoxymethylene)benzeneacetate
    • Coumoxystrobin [ISO]
    • SYP 3375
    • Q19277625
    • methyl (2E)-2-(2-{[(3-butyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]methyl}phenyl)-3-methoxyprop-2-
    • 850881-70-8
    • UNII-521R9X5RXY
    • methyl (betaE)-2-[[(3-butyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]methyl]-alpha-(methoxymethylene)benzeneacetate
    • methyl (2E)-2-(2-{[(3-butyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]methyl}phenyl)-3-methoxyprop-2-enoate
    • DTXCID6031968
    • CHEBI:83185
    • methyl (2E)-2-(2-(((3-butyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy)methyl)phenyl)-3-methoxyprop-2-enoate
    • SCHEMBL18292073
    • Coumoxystrobin; Dingxiangjunzhi; SYP 3375
    • methyl 2-(2-(3-n-butyl-4-methylcoumarin-7-yloxymethyl)phenyl)-3-methoxyacrylate
    • DTXSID7058200
    • methyl (2E)-2-(2-(((3-butyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy)methyl)phenyl)-3-methoxyprop-2-enoate
    • CHEMBL2286960
    • methyl (betaE)-2-(((3-butyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy)methyl)-alpha-(methoxymethylene)benzeneacetate
    • BENZENEACETIC ACID, 2-(((3-BUTYL-4-METHYL-2-OXO-2H-1-BENZOPYRAN-7-YL)OXY)METHYL)-.ALPHA.-(METHOXYMETHYLENE)-, METHYL ESTER, (.ALPHA.E)-
    • methyl (2E)-2-(2-{[(3-butyl-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]methyl}phenyl)-3-methoxyprop-2-enoate
    • SYP-3375
    • BENZENEACETIC ACID, 2-(((3-BUTYL-4-METHYL-2-OXO-2H-1-BENZOPYRAN-7-YL)OXY)METHYL)-ALPHA-(METHOXYMETHYLENE)-, METHYL ESTER, (ALPHAE)-
    • Inchi: 1S/C26H28O6/c1-5-6-10-21-17(2)20-13-12-19(14-24(20)32-26(21)28)31-15-18-9-7-8-11-22(18)23(16-29-3)25(27)30-4/h7-9,11-14,16H,5-6,10,15H2,1-4H3/b23-16+
    • InChI Key: CWVRPJSBNHNJSI-XQNSMLJCSA-N
    • SMILES: O1C(C(=C(C)C2C=CC(=CC1=2)OCC1C=CC=CC=1/C(=C\OC)/C(=O)OC)CCCC)=O

Computed Properties

  • Exact Mass: 436.18858861g/mol
  • Monoisotopic Mass: 436.18858861g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 32
  • Rotatable Bond Count: 10
  • Complexity: 724
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 5.2
  • Topological Polar Surface Area: 71.1

Coumoxystrobin Pricemore >>

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Coumoxystrobin Production Method

Production Method 1

Reaction Conditions
1.1 -
1.2 -
1.3 Reagents: Sodium carbonate Solvents: Dimethylformamide ;  80 °C
Reference
Design, synthesis and fungicidal activity of Coumoxystrobin (SYP-3375)
Li, Miao; Liu, Changling; Zhang, Mingxing; Guan, Aiying; Zhang, Hong; et al, Nongyaoxue Xuebao, 2010, 12(4), 453-457

Production Method 2

Reaction Conditions
1.1 Reagents: Sodium hydride Solvents: Dimethylformamide ;  0.5 h, rt
1.2 3 h, rt
Reference
Design, synthesis and structure-activity relationship of novel coumarin derivatives
Guan, Ai-Ying; Liu, Chang-Ling; Li, Miao; Zhang, Hong; Li, Zhi-Nian; et al, Pest Management Science, 2011, 67(6), 647-655

Coumoxystrobin Raw materials

Coumoxystrobin Preparation Products

Coumoxystrobin Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:850881-70-8)Coumoxystrobin
Order Number:LE10638
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:03
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:850881-70-8)Coumoxystrobin
Order Number:sfd20835
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally

Additional information on Coumoxystrobin

Coumoxystrobin (CAS No. 850881-70-8): A Comprehensive Guide to Its Properties and Applications

Coumoxystrobin (CAS No. 850881-70-8) is a highly effective fungicide belonging to the strobilurin class of compounds. Known for its broad-spectrum activity, it is widely used in agriculture to protect crops from fungal diseases. The compound's unique chemical structure, featuring a coumarin moiety, enhances its stability and efficacy, making it a preferred choice for modern integrated pest management (IPM) systems.

In recent years, the demand for sustainable agricultural solutions has surged, driven by concerns over food security and environmental impact. Coumoxystrobin addresses these challenges by offering a balance between high performance and reduced ecological footprint. Its mode of action involves inhibiting mitochondrial respiration in fungi, which disrupts energy production and leads to cell death. This mechanism is particularly effective against resistant fungal strains, a growing concern in global agriculture.

The versatility of Coumoxystrobin extends to its compatibility with various crops, including cereals, fruits, and vegetables. Farmers and agronomists frequently search for information on its application rates, mixing compatibility, and residual effects. Studies have shown that when used as part of a rotational fungicide program, it significantly reduces the risk of resistance development, a topic of high interest among researchers and practitioners alike.

Another hot topic in the agricultural sector is the impact of climate change on crop diseases. Rising temperatures and humidity levels create favorable conditions for fungal outbreaks, necessitating robust solutions like Coumoxystrobin. Its ability to perform under diverse environmental conditions makes it a reliable tool for farmers adapting to climate variability. Additionally, its low toxicity to non-target organisms aligns with the principles of eco-friendly farming.

From a technical perspective, Coumoxystrobin is characterized by its high systemic activity and long-lasting protection. These properties are critical for ensuring consistent crop yields, especially in regions prone to disease pressure. The compound's formulation options, such as wettable powders and suspension concentrates, cater to different application needs, further enhancing its practicality.

As the agricultural industry evolves, so does the interest in innovative crop protection strategies. Coumoxystrobin exemplifies this trend by combining scientific advancement with real-world applicability. Whether you're a researcher exploring fungicide modes of action or a farmer seeking effective disease control, this compound offers valuable insights and solutions. Its role in shaping the future of sustainable agriculture cannot be overstated.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:850881-70-8)Coumoxystrobin
LE10638
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:850881-70-8)Coumoxystrobin
sfd20835
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email