Cas no 85006-25-3 (Tert-Butyl (tert-butoxycarbonyl)oxycarbamate)

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate is a specialized carbamate derivative used primarily as a protecting group reagent in organic synthesis. Its key advantage lies in its ability to selectively protect amines under mild conditions, offering stability against a range of reaction environments while allowing for facile deprotection under acidic conditions. The tert-butoxycarbonyl (Boc) group enhances solubility in organic solvents, facilitating handling in multi-step syntheses. This compound is particularly valuable in peptide and pharmaceutical chemistry, where precise amine protection is critical. Its robust stability and compatibility with diverse functional groups make it a reliable choice for complex molecular constructions.
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate structure
85006-25-3 structure
Product Name:Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
CAS No:85006-25-3
MF:C10H19NO5
MW:233.261563539505
MDL:MFCD00034797
CID:732608
PubChem ID:2728863
Update Time:2025-06-09

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl (tert-butoxycarbonyl)oxycarbamate
    • N,O-Di-BOC-hydroxylamine
    • N,O-Bis(tert-butoxycarbonyl)hydroxylamine
    • Carbonic acid,[[(1,1-dimethylethoxy)carbonyl]azanyl] 1,1-dimethylethyl ester
    • NULL
    • tert-butyl [(2-methylpropan-2-yl)oxycarbonylamino] carbonate
    • tert-Butyl [(tert-butoxycarbonyl)oxy]carbamate
    • tert-Butyl-N-(tert-butoxycarbonyloxy)carbamate
    • TERT-BUTYL N-(TERT-BUTOXYCARBONYLOXY)CARBAMATE
    • N-(tert-Butoxycarbonyloxy)carbamic Acid tert-Butyl Ester
    • [(tert-Butoxycarbonyl)oxy]carbamic acid tert-butyl ester
    • Carbonic acid [[(1,1-dimethylethoxy)carbonyl]azanyl] 1,1-dimethylethyl ester
    • tert-Butyl (((1,1-dimethylethoxy)carbonyl)oxy)carbamate
    • (tert-Butoxycarbonylamino) tert-butyl carbonate
    • tert-Butyl tert-Butoxycarbonyloxycarbamate
    • 2-{[({[(tert-butoxy)carbonyl]amino}oxy)carbonyl]oxy}-2-meth
    • Carbamic acid, (tert-butoxycarbonyloxy)-, tert-butyl ester (6CI)
    • Carbamic acid, [[(1,1-dimethylethoxy)carbonyl]oxy]-, 1,1-dimethylethyl ester (9CI)
    • 2-[[([[(tert-Butoxy)carbonyl]amino]oxy)carbonyl]oxy]-2-methylpropane
    • N,O-(tert-Butoxycarbonyl)hydroxylamine
    • tert-Butyl (tert-butoxycarbonyloxy)carbamate
    • n,o-di-tert-butoxycarbonylhydroxylamine
    • tert-Butyl (Boc)oxycarbamate
    • 85006-25-3
    • N,O-Bis-tert-butoxycarbonylhydroxylamine
    • J-524378
    • SCHEMBL1609396
    • DTXSID20234067
    • NS00038737
    • UNII-HX6G035C2M
    • N,O-di-(tert-butoxycarbonyl)hydroxylamine
    • HX6G035C2M
    • EN300-160280
    • AKOS000268207
    • SY052917
    • tert-butyl N-(tert-butoxycarbonyloxy)-carbamate
    • ALBB-022890
    • B4780
    • (tert-butoxy)carbonylamino (tert-butoxy)formate
    • MFCD00034797
    • STR09380
    • 2-[({[(TERT-BUTOXYCARBONYL)AMINO]OXY}CARBONYL)OXY]-2-METHYLPROPANE
    • EINECS 285-055-0
    • AC2557
    • N,O-Di-Boc hydroxylamine
    • N-t-butoxycarbonyl-N-t-butoxycarbonyloxyamine
    • BBL102218
    • 2-((((((TERT-BUTOXY)CARBONYL)AMINO)OXY)CARBONYL)OXY)-2-METHYLPROPANE
    • t-butyl N-(t-butoxycarbonyloxy)carbamate
    • N,O-Di-Boc-hydroxylamine, 97%
    • carbamic acid, [[(1,1-dimethylethoxy)carbonyl]oxy]-, 1,1-dimethylethyl ester
    • N,O-bis(t-butoxycarbonyl)hydroxylamine
    • tert-Butyl(tert-butoxycarbonyl)oxycarbamate
    • N,O-bis-BOC-hydroxylamine
    • STL556017
    • CS-W018709
    • CARBONIC ACID, (((1,1-DIMETHYLETHOXY)CARBONYL)AZANYL) 1,1-DIMETHYLETHYL ESTER
    • 2-{[({[(tert-butoxy)carbonyl]amino}oxy)carbonyl]oxy}-2-methylpropane
    • Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
    • MDL： MFCD00034797
    • Inchi： 1S/C10H19NO5/c1-9(2,3)14-7(12)11-16-8(13)15-10(4,5)6/h1-6H3,(H,11,12)
    • InChI Key： AGOSGCWATIJZHQ-UHFFFAOYSA-N
    • SMILES： O=C(OC(C)(C)C)ONC(OC(C)(C)C)=O
    • BRN： 1794022

Computed Properties

  • Exact Mass: 233.12600
  • Monoisotopic Mass: 233.12632271g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 6
  • Complexity: 261
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 73.9
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: 2.4

Experimental Properties

  • Color/Form: White crystals
  • Density: 1.080
  • Melting Point: 67.0 to 71.0 deg-C
  • PSA: 73.86000
  • LogP: 2.76870
  • Solubility: Not determined

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Security Information

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Customs Data

  • HS CODE：2924199090
  • Customs Data：

    China Customs Code:

    2924199090

    Overview:

    2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
N159505-5G
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3 ≥98.0%
5g
 ￥70.90 2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
N159505-25g
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3 ≥98.0%
25g
 ￥278.90 2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
N159505-100g
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3 ≥98.0%
100g
 ￥896.90 2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
N159505-1G
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3 ≥98.0%
1g
 ￥29.90 2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
N159505-10g
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3 ≥98.0%
10g
 ￥115.90 2023-09-01
TRC
B700648-50mg
tert-Butyl (tert-Butoxycarbonyl)oxycarbamate
 85006-25-3
50mg
 $ 50.00 2022-06-06
TRC
B700648-100mg
tert-Butyl (tert-Butoxycarbonyl)oxycarbamate
 85006-25-3
100mg
 $ 65.00 2022-06-06
TRC
B700648-500mg
tert-Butyl (tert-Butoxycarbonyl)oxycarbamate
 85006-25-3
500mg
 $ 80.00 2022-06-06
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
412791-1G
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3 97%
1G
 ￥724.97 2022-02-24
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
412791-5G
Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
 85006-25-3
5g
 ￥678.93 2023-12-06

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Triethylamine ,  Hydroxyamine hydrochloride Solvents: tert-Butyl methyl ether ,  Water
Reference
A facile synthesis of N,O-bis(tert-butoxycarbonyl)hydroxylamine
Staszak, Michael A.; et al, Tetrahedron Letters, 1993, 34(44), 7043-4

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Raw materials

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Preparation Products

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:85006-25-3)Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
Order Number:A863827
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 08:43
Price ($):366.0

Tert-Butyl (tert-butoxycarbonyl)oxycarbamate Related Literature

Related Categories

85006-25-3 (Tert-Butyl (tert-butoxycarbonyl)oxycarbamate) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:85006-25-3)Tert-Butyl (tert-butoxycarbonyl)oxycarbamate
A863827
Purity:99%
Quantity:100g
Price ($):366.0
Email