• 1. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
  Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
• 2. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
• 3. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
• 4. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 5. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583

Chemical Profile of [4-(hydroxymethyl)piperidin-4-yl]methanol (CAS No. 848070-24-6)

[4-(hydroxymethyl)piperidin-4-yl]methanol is a significant compound in the field of pharmaceutical chemistry, characterized by its unique structural and functional properties. This compound, identified by the CAS number 848070-24-6, has garnered attention due to its potential applications in drug development and molecular research. The presence of a piperidine ring and a hydroxymethyl substituent makes it a versatile intermediate for synthesizing more complex molecules.

The chemical structure of [4-(hydroxymethyl)piperidin-4-yl]methanol consists of a six-membered heterocyclic ring containing nitrogen, which is a key feature for its reactivity and biological activity. This piperidine moiety is particularly important in medicinal chemistry, as it is frequently found in bioactive molecules that interact with biological targets. The hydroxymethyl group attached to the fourth position of the piperidine ring further enhances its potential for further functionalization, making it a valuable building block in synthetic chemistry.

In recent years, there has been growing interest in developing new therapeutic agents that leverage the unique properties of piperidine derivatives. [4-(hydroxymethyl)piperidin-4-yl]methanol has been explored in various research studies for its potential role in modulating biological pathways. For instance, studies have suggested that compounds with similar structures may exhibit inhibitory effects on certain enzymes and receptors, which are relevant to diseases such as cancer and neurodegenerative disorders. The hydroxymethyl group provides a site for further chemical modifications, allowing researchers to tailor the molecule's properties for specific applications.

One of the most promising areas of research involving [4-(hydroxymethyl)piperidin-4-yl]methanol is its use as a precursor in the synthesis of novel drug candidates. The piperidine ring is known to be a common pharmacophore in many drugs, contributing to their binding affinity and selectivity. By incorporating this moiety into new molecules, researchers can potentially enhance the efficacy and reduce side effects of existing therapies. Additionally, the hydroxymethyl group can be oxidized to form aldehydes or carboxylic acids, providing multiple pathways for structural diversification.

The synthesis of [4-(hydroxymethyl)piperidin-4-yl]methanol involves multi-step organic reactions that require careful optimization to ensure high yield and purity. Common synthetic routes include nucleophilic substitution reactions on halogenated piperidine derivatives followed by reduction or hydroxylation steps. Advances in catalytic methods have also enabled more efficient and sustainable synthesis strategies, which are increasingly important in pharmaceutical research. These methods often involve transition metal catalysts that facilitate selective transformations while minimizing waste.

In addition to its pharmaceutical applications, [4-(hydroxymethyl)piperidin-4-yl]methanol has shown potential in materials science and chemical biology. Its ability to form stable complexes with other molecules makes it useful for developing new analytical tools and probes for studying biological systems. For example, researchers have explored its use in creating ligands for metal ions or as a component in self-assembling systems. These applications highlight the broad utility of this compound beyond traditional drug development.

The latest research on [4-(hydroxymethyl)piperidin-4-yl]methanol has focused on understanding its interactions with biological targets at a molecular level. Techniques such as nuclear magnetic resonance (NMR) spectroscopy, X-ray crystallography, and computational modeling have been employed to elucidate its binding mechanisms. These studies have provided valuable insights into how the compound interacts with enzymes and receptors, which can inform the design of next-generation therapeutics. The findings from these studies are also contributing to our broader understanding of how piperidine derivatives function in biological systems.

As the field of medicinal chemistry continues to evolve, [4-(hydroxymethyl)piperidin-4-yl]methanol remains a compound of significant interest due to its structural versatility and functional potential. Ongoing research aims to uncover new synthetic routes that improve efficiency and sustainability while expanding its applications in drug discovery and beyond. The integration of cutting-edge technologies such as artificial intelligence (AI) and machine learning (ML) is also facilitating faster identification of promising derivatives from this class of compounds.

In conclusion, [4-(hydroxymethyl)piperidin-4-yl]methanol (CAS No. 848070-24-6) represents an important advancement in pharmaceutical chemistry with far-reaching implications for drug development and scientific research. Its unique structural features make it a valuable intermediate for synthesizing complex molecules, while its potential biological activities continue to be explored through rigorous scientific investigation. As our understanding of this compound grows, so too does its promise for addressing some of the most pressing challenges in medicine today.

• 20691-89-8((1-methylpiperidin-4-yl)methanol)
• 328274-46-0(4-Piperidinemethanol, 1-propyl-)
• 26608-58-2(1-azabicyclo2.2.2octan-4-ylmethanol)
• 141430-48-0(4-Piperidinemethanol, 1-pentyl-)
• 1256643-15-8((4-Ethylpiperidin-4-yl)methanol)
• 141060-33-5(2-1-(4-aminobutyl)piperidin-4-ylpropan-1-ol)
• 148703-15-5((1-Butyl-piperidin-4-yl)-methanol)
• 297172-16-8((4-Methylpiperidin-4-yl)methanol)
• 1354792-85-0((4-Methylpiperidin-4-yl)methanol hydrochloride)
• 90226-87-2((1-Ethylpiperidin-4-YL)methanol)