Cas no 84762-68-5 (4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine)
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine is a heterocyclic compound featuring a pyrimidine core substituted with a chloro group, a 4-methyl-piperazinyl moiety, and an amine functional group. This structure imparts versatility in synthetic applications, particularly in pharmaceutical and agrochemical research, where it serves as a key intermediate for the development of biologically active molecules. The presence of both electron-donating (amine) and electron-withdrawing (chloro) groups enhances its reactivity in nucleophilic substitution and cross-coupling reactions. The 4-methyl-piperazine substituent further contributes to solubility and binding affinity in target interactions. Its well-defined synthetic route and stability under standard conditions make it a reliable building block for medicinal chemistry and drug discovery efforts.
84762-68-5 structure
Product Name:4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine
CAS No:84762-68-5
MF:C9H14ClN5
MW:227.693959712982
MDL:MFCD00473296
CID:892505
PubChem ID:1085197
Update Time:2025-06-07
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine Chemical and Physical Properties
Names and Identifiers
-
- 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-5-amine
- 4-CHLORO-6-(4-METHYL-PIPERAZIN-1-YL)-PYRIMIDIN-5-YLAMINE
- 4-Chloro-6-(4-methyl-piperazin-1-yl)pyrimidin-5-ylamine
- 6-chloro-4-(4-methylpiperazinyl)pyrimidine-5-ylamine
- [4-chloro-6-(4-methylpiperazino)pyrimidin-5-yl]amine
- 4-chloro-6-(4-methyl-1-piperazinyl)-5-pyrimidinamine
- HMS2697C16
- SR-01000363051-1
- DTXSID50360166
- 84762-68-5
- cid_1085197
- TS-00575
- AKOS000301026
- SMR000287015
- 4-chloranyl-6-(4-methylpiperazin-1-yl)pyrimidin-5-amine
- SR-01000363051
- CHEMBL1702150
- BRD-K63361769-001-06-3
- BDBM45628
- 4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine, AldrichCPR
- FT-0677145
- A864009
- CS-0326287
- MLS000709852
- DB-076107
- 4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine
-
- MDL： MFCD00473296
- Inchi： 1S/C9H14ClN5/c1-14-2-4-15(5-3-14)9-7(11)8(10)12-6-13-9/h6H,2-5,11H2,1H3
- InChI Key： YFUZRBRRNUSCQO-UHFFFAOYSA-N
- SMILES： ClC1=C(C(=NC=N1)N1CCN(C)CC1)N
Computed Properties
- Exact Mass: 227.09400
- Monoisotopic Mass: 227.093773g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 15
- Rotatable Bond Count: 1
- Complexity: 207
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- XLogP3: 0.8
- Topological Polar Surface Area: 58.3?2
Experimental Properties
- PSA: 58.28000
- LogP: 1.04810
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine Security Information
- Hazard Category Code： 22
-
Hazardous Material Identification：
- HazardClass：IRRITANT
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | C011175-50mg |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 50mg |
$ 100.00 | 2022-06-01 | ||
| TRC | C011175-100mg |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 100mg |
$ 160.00 | 2022-06-01 | ||
| Chemenu | CM165011-5g |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 95% | 5g |
$777 | 2021-08-05 | |
| Matrix Scientific | 011006-1g |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 1g |
$308.00 | 2023-09-06 | ||
| Matrix Scientific | 011006-500mg |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 500mg |
$200.00 | 2023-09-06 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 011006-1g |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 1g |
5005.0CNY | 2021-07-07 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 011006-500mg |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 500mg |
3251.0CNY | 2021-07-07 | ||
| Chemenu | CM165011-1g |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine |
84762-68-5 | 95% | 1g |
$*** | 2023-05-29 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1396957-1g |
4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-5-amine |
84762-68-5 | 95+% | 1g |
￥2195.00 | 2024-07-28 | |
| Ambeed | A374282-1g |
4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-5-amine |
84762-68-5 | 95+% | 1g |
$217.0 | 2025-04-16 |
4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine Related Literature
-
Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
-
Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
-
4. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
84762-68-5 (4-Chloro-6-(4-methyl-piperazin-1-yl)-pyrimidin-5-ylamine) Related Products
- 203519-89-5(4-Chloro-6-(piperazin-1-yl)pyrimidine hydrochloride)
- 41259-67-0(N'4'-Butyl-6-chloro-pyrimidine-4,5-diamine)
- 84762-70-9(4-Chloro-6-piperidin-1-yl-pyrimidin-5-ylamine)
- 88627-16-1(Ethanol, 2,2'-[(5-amino-6-chloro-4-pyrimidinyl)imino]bis-)
- 18202-82-9(6-chloro-4-N-(propan-2-yl)pyrimidine-4,5-diamine)
- 130623-81-3(6-Chloro-N4,N4-dimethylpyrimidine-4,5-diamine)
- 373356-50-4(4-chloro-6-(piperazin-1-yl)pyrimidine)
- 195252-56-3(6-chloro-4-N-propylpyrimidine-4,5-diamine)
- 88627-25-2(Pteridine, 4-chloro-8-(2-chloroethyl)-5,6,7,8-tetrahydro-)
- 98140-03-5(6-chloro-N4-ethylpyrimidine-4,5-diamine)
Recommended suppliers
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Essenoi Fine Chemical Co., Limited
Gold Member
Audited Supplier
CN Supplier
Reagent
Hunan Well Medicine Synthesis Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
PRIBOLAB PTE.LTD
Gold Member
Audited Supplier
CN Supplier
Reagent
