Cas no 84478-67-1 (BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO-)
BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO- Chemical and Physical Properties
Names and Identifiers
-
- BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO-
- 4-bromo-5-ethoxy-2-fluoroaniline
- 4-bromo-5-ethoxy-2-fluorobenzenamine
- 84478-67-1
- SB80798
- SCHEMBL7893305
- RNCJZYXRZHUKQJ-UHFFFAOYSA-N
-
- Inchi: 1S/C8H9BrFNO/c1-2-12-8-4-7(11)6(10)3-5(8)9/h3-4H,2,11H2,1H3
- InChI Key: RNCJZYXRZHUKQJ-UHFFFAOYSA-N
- SMILES: C1(N)=CC(OCC)=C(Br)C=C1F
Computed Properties
- Exact Mass: 232.98515Da
- Monoisotopic Mass: 232.98515Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 147
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.4
- Topological Polar Surface Area: 35.3?2
BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A019148938-1g |
4-Bromo-5-ethoxy-2-fluoroaniline |
84478-67-1 | 97% | 1g |
$707.20 | 2023-08-31 | |
| Crysdot LLC | CD12026038-1g |
4-Bromo-5-ethoxy-2-fluoroaniline |
84478-67-1 | 97% | 1g |
$680 | 2024-07-24 |
BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO- Related Literature
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Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
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Ying Li,Weirong Yao,Yunfei Xie,Renjun Pei RSC Adv., 2015,5, 98724-98729
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Jianyao Huang,Dong Gao,Zhihui Chen,Weifeng Zhang Polym. Chem., 2021,12, 2471-2480
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Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
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José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
Additional information on BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO-
Introduction to BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO (CAS No. 84478-67-1)
BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO, identified by its Chemical Abstracts Service (CAS) number 84478-67-1, is a fluorinated aromatic amine derivative that has garnered significant attention in the field of medicinal chemistry and drug discovery. This compound belongs to a class of molecules that exhibit diverse biological activities, making it a valuable scaffold for developing novel therapeutic agents. The structural features of 4-BROMO-5-ETHOXY-2-FLUORO benzeneamine, including the presence of bromine, ethoxy, and fluoro substituents, contribute to its unique chemical properties and reactivity, which are exploited in synthetic chemistry and pharmacological studies.
The synthesis and application of BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO have been explored in several cutting-edge research studies. One notable area of interest is its potential as a precursor in the development of kinase inhibitors. Kinases are enzymes that play a crucial role in cell signaling pathways, and their dysregulation is associated with various diseases, including cancer. The fluorine atom in the molecule enhances metabolic stability and binding affinity, which are critical factors for designing effective kinase inhibitors. Recent studies have demonstrated that derivatives of this compound can selectively inhibit specific kinases, thereby opening up new avenues for targeted therapy.
In addition to its role in kinase inhibition, 4-BROMO-5-ETHOXY-2-FLUORO benzeneamine has been investigated for its antimicrobial properties. The bromine and fluoro substituents contribute to the compound's ability to disrupt bacterial cell membranes and inhibit bacterial growth. This has led to research into its potential use as an antimicrobial agent against drug-resistant bacteria. Preliminary studies have shown promising results in vitro, suggesting that further investigation could lead to the development of new antibiotics based on this scaffold.
The ethoxy group in BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO also plays a significant role in modulating the biological activity of the molecule. Ethoxy-substituted aromatic compounds are known to exhibit a wide range of pharmacological effects, including anti-inflammatory and analgesic properties. Researchers have explored the use of this compound in designing novel anti-inflammatory drugs by leveraging its structural flexibility and ability to interact with various biological targets. The combination of bromine, ethoxy, and fluoro substituents makes this molecule a versatile tool for medicinal chemists seeking to develop innovative therapeutic strategies.
Recent advances in computational chemistry have further enhanced the understanding of the interactions between BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO and biological targets. Molecular docking studies have revealed that this compound can bind effectively to a variety of protein receptors, including those involved in pain perception and immune response. These findings have guided the design of more potent derivatives with improved pharmacokinetic profiles. The use of computational methods has not only accelerated the drug discovery process but also provided insights into the molecular mechanisms underlying the biological activity of this compound.
The synthetic pathways for 4-BROMO-5-ETHOXY-2-FLUORO benzeneamine have also been refined through recent innovations in organic synthesis. Researchers have developed efficient methods for introducing the bromo, ethoxy, and fluoro groups onto the benzene ring while maintaining high selectivity and yield. These advancements have made it possible to produce larger quantities of the compound for both research and commercial purposes. The ability to synthesize complex fluorinated aromatic amines like BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO has significantly contributed to the growth of fluorinated pharmaceuticals, which are known for their improved bioavailability and therapeutic efficacy.
The future prospects for BENZENAMINE, 4-BROMO-5-ETHOXY-2-FLUORO are promising, with ongoing research aimed at expanding its applications in medicine and biotechnology. Investigations into its potential as an intermediate in the synthesis of agrochemicals are also underway. The unique structural features of this compound make it a valuable building block for creating novel molecules with enhanced crop protection properties. As our understanding of its chemical properties and biological activities continues to grow, so too will its significance in various scientific disciplines.
In conclusion,BENZENAMINE, 4-BROMO-5-EThylOXy-Z-FluOrOl (CAS No. 84478671) represents a fascinating example of how structural modifications can lead to compounds with diverse biological activities. Its role in developing kinase inhibitors,antimicrobial agents,and anti-inflammatory drugs underscores its importance in modern medicinal chemistry。With further research,this compound is poised to make significant contributions to therapeutic innovation across multiple fields。
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