Cas no 84228-46-6 (Ethyl 4-amino-2-nitrobenzoate)

Ethyl 4-amino-2-nitrobenzoate is a nitro-substituted aromatic ester with the molecular formula C9H10N2O4. This compound is characterized by the presence of both an amino (–NH2) and a nitro (–NO2) functional group on the benzene ring, which makes it a versatile intermediate in organic synthesis. Its ester group enhances solubility in organic solvents, facilitating its use in reactions such as azo dye synthesis, pharmaceutical intermediates, and agrochemical applications. The electron-withdrawing nitro group and electron-donating amino group provide unique reactivity, enabling selective functionalization. The compound is typically supplied as a crystalline solid with high purity, ensuring consistent performance in research and industrial processes.
Ethyl 4-amino-2-nitrobenzoate structure
Ethyl 4-amino-2-nitrobenzoate structure
Product Name:Ethyl 4-amino-2-nitrobenzoate
CAS No:84228-46-6
MF:C9H10N2O4
MW:210.186702251434
MDL:MFCD06656140
CID:720851
PubChem ID:22832069
Update Time:2025-06-07

Ethyl 4-amino-2-nitrobenzoate Chemical and Physical Properties

Names and Identifiers

    • Ethyl 4-amino-2-nitrobenzoate
    • 4-AMINO-2-NITROBENZOIC ACID ETHYL ESTER
    • 4-Amino-2-Nitro-Benzoic Acid Ethyl Ester
    • Benzoic acid,4-amino-2-nitro-, ethyl ester
    • DB-000704
    • EN300-6245469
    • DS-18192
    • AKOS015998782
    • SCHEMBL8771665
    • Ethyl4-amino-2-nitrobenzoate
    • CL8513
    • Benzoic acid, 4-amino-2-nitro-, ethyl ester
    • SB79388
    • CS-0151833
    • 84228-46-6
    • DTXSID30628574
    • YOMQIQZTFBDFSR-UHFFFAOYSA-N
    • MDL： MFCD06656140
    • Inchi： 1S/C9H10N2O4/c1-2-15-9(12)7-4-3-6(10)5-8(7)11(13)14/h3-5H,2,10H2,1H3
    • InChI Key： YOMQIQZTFBDFSR-UHFFFAOYSA-N
    • SMILES： O=C(C1C([N+](=O)[O-])=CC(N)=CC=1)OCC

Computed Properties

  • Exact Mass: 210.06400
  • Monoisotopic Mass: 210.064
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 4
  • Complexity: 251
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.5
  • Topological Polar Surface Area: 98.1A^2

Experimental Properties

  • Density: 1.33
  • Boiling Point: 397.6°C at 760 mmHg
  • Flash Point: 194.3°C
  • Refractive Index: 1.591
  • PSA: 98.14000
  • LogP: 2.45810

Ethyl 4-amino-2-nitrobenzoate Customs Data

  • HS CODE：2922499990
  • Customs Data：

    China Customs Code:

    2922499990

    Overview:

    2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    P.Imported animals and plants\Quarantine of animal and plant products
    Q.Outbound animals and plants\Quarantine of animal and plant products
    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Ethyl 4-amino-2-nitrobenzoate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
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Ethyl 4-amino-2-nitrobenzoate
 84228-46-6 95%
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 $312.00 2023-08-31
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TRC
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Ethyl 4-amino-2-nitrobenzoate
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SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
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4-Amino-2-Nitro-Benzoic Acid Ethyl Ester
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Ethyl 4-amino-2-nitrobenzoate Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Sulfuric acid Solvents: Ethanol ;  reflux
Reference
Novel curcumin derivatives as P-glycoprotein inhibitors: Molecular modeling, synthesis and sensitization of multidrug resistant cells to doxorubicin
Sagnou, Marina; Novikov, Fedor N.; Ivanova, Ekaterina S.; Alexiou, Polyxeni; Stroylov, Victor S.; et al, European Journal of Medicinal Chemistry, 2020, 198,

Ethyl 4-amino-2-nitrobenzoate Raw materials

Ethyl 4-amino-2-nitrobenzoate Preparation Products

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