Production Method 1

655-26-5

842169-71-5

Reaction Conditions

1.1 Reagents: Lithium bis(trimethylsilyl)amide Solvents: Toluene ,  Tetrahydrofuran ;  10 min, rt; 15 min, rt
1.2 Reagents: (Dimethyl sulfide)trihydroboron Solvents: Toluene ;  20 min, rt; rt → 0 °C
1.3 Reagents: Sodium hydroxide Solvents: Water ;  5 min, rt; 90 min, rt
1.4 Reagents: Hydrochloric acid Solvents: Diethyl ether ,  Toluene ,  1,4-Dioxane ;  rt

Reference

Unprecedented Catalytic Asymmetric Reduction of N-H Imines

Gosselin, Francis; O'Shea, Paul D.; Roy, Stephanie; Reamer, Robert A.; Chen, Cheng-Yi; et al, Organic Letters, 2005, 7(2), 355-358

1-(3-Bromo-phenyl)-2,2,2-trifluoro-ethylamine hydrochloride Raw materials

• 3'-Bromo-2,2,2-trifluoroacetophenone

1-(3-Bromo-phenyl)-2,2,2-trifluoro-ethylamine hydrochloride Preparation Products

• 1-(3-Bromo-phenyl)-2,2,2-trifluoro-ethylamine hydrochloride (842169-71-5)

• 1. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 2. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 3. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 4. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
• 5. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Bromobenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Bromobenzenes

• 842169-72-6(1-(4-bromophenyl)-2,2,2-trifluoroethan-1-amine hydrochloride)
• 843608-46-8(1-(4-bromophenyl)-2,2,2-trifluoroethan-1-amine)
• 843608-54-8((1R)-1-(3-Bromophenyl)-2,2,2-trifluoroethylamine)
• 878539-31-2((S)-1-(3-Bromophenyl)-2,2,2-trifluoroethanamine)
• 336105-43-2((s)-1-(4-Bromophenyl)-2,2,2-trifluoroethanamine Hydrochloride)
• 843608-53-7((1R)-1-(4-bromophenyl)-2,2,2-trifluoroethan-1-amine)
• 778565-93-8((1S)-1-(4-bromophenyl)-2,2,2-trifluoroethan-1-amine)
• 842169-83-9((R)-1-(4-Bromophenyl)-2,2,2-trifluoroethanamine hydrochloride)
• 878408-46-9((s)-1-(3-Bromophenyl)-2,2,2-trifluoroethan-1-amine Hydrochloride Salt)
• 843608-45-7(1-(3-bromophenyl)-2,2,2-trifluoroethan-1-amine)