Cas no 83873-17-0 ((9b,11b)-Epoxy Fluorometholone Acetate)

(9b,11b)-Epoxy Fluorometholone Acetate is a synthetic corticosteroid derivative characterized by its unique epoxy and acetate functional groups. This compound exhibits potent anti-inflammatory and immunosuppressive properties, making it valuable in pharmaceutical research and development. The epoxy modification at the 9b,11b-positions enhances its metabolic stability, while the acetate group improves lipophilicity, facilitating better tissue penetration. It demonstrates high glucocorticoid receptor affinity, contributing to its efficacy in modulating inflammatory responses. The structural features of this molecule also reduce systemic side effects compared to traditional corticosteroids. Its chemical stability and predictable pharmacokinetics make it a reliable candidate for further investigation in targeted therapeutic applications.
(9b,11b)-Epoxy Fluorometholone Acetate structure
83873-17-0 structure
Product Name:(9b,11b)-Epoxy Fluorometholone Acetate
CAS No:83873-17-0
MF:C24H30O5
MW:398.492007732391
CID:1061951
PubChem ID:71316376
Update Time:2025-07-02

(9b,11b)-Epoxy Fluorometholone Acetate Chemical and Physical Properties

Names and Identifiers

    • (9β,11β)-Epoxy Fluorometholone Acetate
    • (9B,11B)-EPOXY FLUOROMETHOLONE ACETATE
    • A,11
    • DTXSID80747704
    • (6.ALPHA.,9.BETA.,11.BETA.)-17-(ACETYLOXY)-9,11-EPOXY-6-METHYLPREGNA-1,4-DIENE-3,20-DIONE
    • UNII-W9RK4LC5J5
    • SCHEMBL11272815
    • (9beta,11beta)-Epoxy Fluorometholone Acetate
    • [(1S,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-2,8,15-trimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-14-yl] acetate
    • PREGNA-1,4-DIENE-3,20-DIONE, 17-(ACETYLOXY)-9,11-EPOXY-6-METHYL-, (6.ALPHA.,9.BETA.,11.BETA.)-
    • (9beta,11beta)-Epoxyfluorometholone acetate
    • (1S,2S,8S,10S,11S,14R,15S,17S)-14-Acetyl-2,8,15-trimethyl-5-oxo-18-oxapentacyclo(8.8.0.0(1,17).0(2,7).0(11,15))octadeca-3,6-dien-14-yl acetate
    • Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9,11-epoxy-6-methyl-, (6alpha,9beta,11beta)-
    • 83873-17-0
    • (9.BETA.,11.BETA.)-EPOXYFLUOROMETHOLONE ACETATE
    • (6alpha,9beta,11beta)-17-(Acetyloxy)-9,11-epoxy-6-methylpregna-1,4-diene-3,20-dione
    • W9RK4LC5J5
    • (6alpha,9beta,11beta)-6-Methyl-3,20-dioxo-9,11-epoxypregna-1,4-dien-17-yl acetate
    • (6alpha,9beta,11beta)-17-(Acetyloxy)-9,11-epoxy-6-methylpregna-1,4-diene-3,20-dione;
    • (9b,11b)-Epoxy Fluorometholone Acetate
    • Inchi： 1S/C24H30O5/c1-13-10-19-17-7-9-23(14(2)25,28-15(3)26)22(17,5)12-20-24(19,29-20)21(4)8-6-16(27)11-18(13)21/h6,8,11,13,17,19-20H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24+/m0/s1
    • InChI Key： FNGSLGMFTHFCNV-YKXVNNMCSA-N
    • SMILES： O1[C@H]2C[C@]3(C)[C@@](C(C)=O)(CC[C@H]3[C@@H]3C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]132)=O)OC(C)=O

Computed Properties

  • Exact Mass: 398.20900
  • Monoisotopic Mass: 398.20932405g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 29
  • Rotatable Bond Count: 3
  • Complexity: 901
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 8
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.6
  • Topological Polar Surface Area: 73?2

Experimental Properties

  • PSA: 72.97000
  • LogP: 3.56250

(9b,11b)-Epoxy Fluorometholone Acetate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
E589215-1mg
(9b,11b)-Epoxy Fluorometholone Acetate
 83873-17-0
1mg
 $ 173.00 2023-09-07
TRC
E589215-10mg
(9b,11b)-Epoxy Fluorometholone Acetate
 83873-17-0
10mg
 $ 1367.00 2023-09-07

(9b,11b)-Epoxy Fluorometholone Acetate Production Method

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