Production Method 1

105-13-5

836-41-9

Reaction Conditions

1.1 Catalysts: Manganese zirconium oxide Solvents: Toluene ;  3 h, 1 atm, 80 °C

Reference

Efficient imine synthesis via oxidative coupling of alcohols with amines in an air atmosphere using a mesoporous manganese-zirconium solid solution catalyst

Wu, Shipeng; et al, Catalysis Science & Technology, 2021, 11(3), 810-822

Production Method 2

123-11-5

836-41-9

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Copper ,  Silica Solvents: Toluene ;  0.5 h, 1 atm, 100 °C

Reference

Reductive Amination of Ketones or Amination of Alcohols over Heterogeneous Cu Catalysts: Matching the Catalyst Support with the N-Alkylating Agent

Santoro, Federica; et al, ChemCatChem, 2012, 4(9), 1249-1254

Production Method 3

123-11-5

836-41-9

Reaction Conditions

1.1 2 - 2.1 kPa, 80 °C

Reference

Alkoxy substituted (E,E)-3,6-bis(styryl)pyridazine-a photosensitive mesogen for liquid crystals

Lifka, Thorsten; et al, Tetrahedron, 2008, 64(27), 6551-6560

Production Method 4

857402-61-0

123-11-5

836-41-9

Reaction Conditions

1.1 Solvents: Benzene-d6 ;  1 h, 25 °C

Reference

Readily Available Primary Aminoboranes as Powerful Reagents for Aldimine Synthesis

Junor, Glen P. ; et al, Angewandte Chemie, 2019, 58(9), 2875-2878

Production Method 5

857402-61-0

123-11-5

836-41-9

Reaction Conditions

1.1 Solvents: Benzene-d6 ;  0.5 h, rt

Reference

Cobalt-Catalyzed Deoxygenative Hydroboration of Nitro Compounds and Applications to One-Pot Synthesis of Aldimines and Amides

Gudun, Kristina A.; et al, Advanced Synthesis & Catalysis, 2022, 364(3), 601-611

Production Method 6

123-11-5

836-41-9

Reaction Conditions

1.1 Catalysts: Cobalt ,  Carbon nitride (C3N4) Solvents: Ethanol ,  Formic acid ;  12 h, 70 °C

Reference

Cobalt-Doped g-C3N4 Nanosheets for One-Pot Synthesis of Imines under Mild Conditions

Zhu, Jiukang; et al, ACS Applied Nano Materials, 2023, 6(7), 5127-5135

Production Method 7

2393-23-9

836-41-9

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Ferrous bromide ;  6 h, 110 °C

Reference

A Solvent-Free Process for Synthesis of Imines by Iron-Catalyzed Oxidative Self- or Cross-Condensation of Primary Amines Using Molecular Oxygen as Sole Oxidant

Gopalaiah, Kovuru; et al, Catalysis Letters, 2016, 146(9), 1648-1654

Production Method 8

2393-23-9

836-41-9

Reaction Conditions

1.1 Catalysts: (SP-5-52)-Carbonylhydro[[N,N′-(2,6-pyridinediyl-κN)bis[P,P-bis(1,1-dimethylethyl… ;  160 °C

Reference

Enhanced Reactivities toward Amines by Introducing an Imine Arm to the Pincer Ligand: Direct Coupling of Two Amines To Form an Imine Without Oxidant

He, Li-Peng; et al, Organometallics, 2012, 31(14), 5208-5211

Production Method 9

3585-93-1

836-41-9

Reaction Conditions

1.1 Reagents: Indium trichloride Solvents: Acetonitrile

Reference

An indium mediated efficient chemoselective deoxygenation of N-oxides and nitrones

Ilias, Md.; et al, Tetrahedron Letters, 2002, 43(10), 1877-1879

Production Method 10

103-33-3

105-13-5

836-41-9

Reaction Conditions

1.1 Reagents: Cesium hydroxide Catalysts: 1,10-Phenanthroline ,  Cobalt (reaction product with 1,10-phenanthroline/HMTA/Melamine, carbon-suppor…) Solvents: Toluene ;  24 h, 130 °C

Reference

Heterogeneous cobalt-catalyzed degradation of azo compounds using alcohols as the stoichiometric hydrogen source

Panja, Dibyajyoti; et al, Journal of Environmental Chemical Engineering, 2023, 11(2),

Production Method 11

104-87-0

836-41-9

Reaction Conditions

1.1 Solvents: Ethanol ;  3 h, reflux

Reference

Synthesis of structurally diverse 2-azetidinones via Staudinger reaction on a solid support

Jarrahpour, Aliasghar; et al, Bulletin of the Chemical Society of Japan, 2011, 84(3), 320-327

Production Method 12

105-13-5

622-37-7

836-41-9

Reaction Conditions

1.1 Reagents: Triphenylphosphine ,  Potassium hydroxide Catalysts: (OC-6-12)-Dichloro[4-[[(S)-ethylthio-κS]methyl]acridine-κN](triphenylphosphine)r… Solvents: Toluene ;  rt → 135 °C; 18 h, 135 °C

Reference

Acceptorless dehydrogenative construction of C=N and C=C bonds through catalytic aza-Wittig and Wittig reactions in the presence of an air-stable ruthenium pincer complex

Biswas, Nandita; et al, Dalton Transactions, 2019, 48(19), 6501-6512

Production Method 13

105-13-5

622-37-7

836-41-9

Reaction Conditions

1.1 Reagents: Potassium tert-butoxide Catalysts: 2633072-21-4 Solvents: Toluene ;  18 h, 130 °C

Reference

Redox-Neutral Imination of Alcohol with Azide: A Sustainable Alternative to the Staudinger/Aza-Wittig Reaction

Li, Huaifeng; et al, ACS Catalysis, 2021, 11(7), 4071-4076

Production Method 14

123-11-5

836-41-9

Reaction Conditions

1.1 Catalysts: Titanium tetrabutoxide Solvents: Tetrahydrofuran ;  rt; 54 h, rt
1.2 Reagents: Water ;  rt; 1 h, rt

Reference

Room temperature metathesis of aryl isocyanates and aromatic aldehydes catalyzed by group(IV) metal alkoxides: An experimental and computational study

Kumar, Akshai; et al, Journal of Organometallic Chemistry, 2010, 695(3), 338-345

Production Method 15

123-11-5

100-52-7

836-41-9

Reaction Conditions

1.1 Solvents: Ethanol ;  20 min, 50 °C

Reference

(R)-oxynitrilases as biocatalysts for the addition of cyanide to phenylimines

Solis O., Aida; et al, Revista Mexicana de Ciencias Farmaceuticas, 2002, 33(4), 27-31

Production Method 16

105-13-5

836-41-9

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Gold alloy, base, Au 65,Pd 35 (nanoparticles, zirconia-supported) Solvents: Ethanol ;  9 h, 40 °C
1.2 1 h, 40 °C

Reference

Au-Pd alloy nanoparticle catalyzed selective oxidation of benzyl alcohol and tandem synthesis of imines at ambient conditions

Cui, Wenjing ; et al, Catalysis Today, 2014, 235, 152-159

Production Method 17

105-13-5

836-41-9

Reaction Conditions

1.1 Catalysts: Cobalt (composite with carbon and nitrogen; carbon nanotube encapsulated) ;  20 h, 160 °C

Reference

Direct reductive coupling of nitroarenes and alcohols catalysed by Co-N-C/CNT@AC

Liu, Di; et al, Green Chemistry, 2019, 21(8), 2129-2137

Production Method 18

105-13-5

836-41-9

Reaction Conditions

1.1 Catalysts: Cobalt Solvents: Octane ;  12 h, 0.6 MPa, 140 °C

Reference

Preparation of Co-N-C catalysts and "one-pot method" for synthesis of N-benzyl aniline

Leng, Jie; et al, Huagong Xuebao (Chinese Edition), 2020, 71(11), 5016-5024

Production Method 19

105-13-5

836-41-9

Reaction Conditions

1.1 Catalysts: 1-Butanaminium, N,N,N-tributyl-, stereoisomer of diaqua[μ10-[orthosilicato(4-)-κ… Solvents: Acetonitrile ,  Toluene ;  4 h, 60 °C; 2 h, 100 °C

Reference

Visible-Light-Responsive Multielectron Redox Catalysis of Lacunary Polyoxometalates Induced by Substrate Coordination to Their Lacuna

Suzuki, Kosuke; et al, Chemistry - An Asian Journal, 2015, 10(1), 144-148

Production Method 20

123-11-5

836-41-9

Reaction Conditions

1.1 Solvents: Benzene ;  4 h, reflux

Reference

Applications of dynamic combinatorial chemistry for the determination of effective molarity

Ciaccia, Maria; et al, Chemical Science, 2015, 6(1), 144-151

Production Method 21

123-11-5

836-41-9

Reaction Conditions

1.1 Reagents: Pinacolborane Catalysts: Cobalt(II) acetylacetonate ,  Bis[2-(diphenylphosphino)phenyl] ether Solvents: Benzene-d6 ;  1 h, rt
1.2 Solvents: Benzene-d6 ;  0.5 h, rt

Reference

Cobalt-Catalyzed Deoxygenative Hydroboration of Nitro Compounds and Applications to One-Pot Synthesis of Aldimines and Amides

Gudun, Kristina A.; et al, Advanced Synthesis & Catalysis, 2022, 364(3), 601-611

Production Method 22

123-11-5

836-41-9

Reaction Conditions

1.1 Reagents: Carbon monoxide ,  Water Catalysts: Gold ,  Titania Solvents: Triethylamine ;  1 h, 5 atm, 25 °C

Reference

Direct one-pot reductive imination of nitroarenes using aldehydes and carbon monoxide by titania supported gold nanoparticles at room temperature

Huang, Jun; et al, Green Chemistry, 2011, 13(10), 2672-2677

Production Method 23

2393-23-9

836-41-9

Reaction Conditions

1.1 Reagents: tert-Butyl hydroperoxide Catalysts: Chitosan (Cu/chitosan bead complex) Solvents: Acetonitrile ;  24 h, 80 °C

Reference

Uniform Cu/chitosan beads as a green and reusable catalyst for facile synthesis of imines via oxidative coupling reaction

Chutimasakul, Threeraphat; et al, RSC Advances, 2020, 10(35), 21009-21018

Production Method 24

3526-43-0

836-41-9

Reaction Conditions

1.1 Reagents: 1,5-Diazabicyclo[4.3.0]non-5-ene Catalysts: Carbon dioxide ,  Eosin Solvents: Dimethyl sulfoxide ;  48 h, 1 atm, 25 - 30 °C

Reference

CO2-Catalyzed Efficient Dehydrogenation of Amines with Detailed Mechanistic and Kinetic Studies

Riemer, Daniel; et al, ACS Catalysis, 2018, 8(12), 11679-11687

Production Method 25

3526-43-0

836-41-9

Reaction Conditions

1.1 Reagents: Sodium borohydride Catalysts: Chloro(triphenylphosphine)gold ,  3,6,9,12-Tetraoxatridecan-1-ol, 13-(4-ethenylphenyl)-, polymer with ethenylbenze… Solvents: Tetrahydrofuran ,  Diglyme ;  rt; 3 h, rt
1.2 Solvents: Mesitylene ;  5 h, 150 °C
1.3 Reagents: Oxygen Solvents: Toluene ;  20 h, 100 °C

Reference

Aerobic oxidation of amines catalyzed by polymer-incarcerated Au nanoclusters: effect of cluster size and cooperative functional groups in the polymer

Miyamura, Hiroyuki; et al, Bulletin of the Chemical Society of Japan, 2011, 84(6), 588-599

Production Method 26

3526-43-0

836-41-9

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Gold ,  Graphite Solvents: Toluene ;  24 h, 110 °C

Reference

Graphite-Supported Gold Nanoparticles as Efficient Catalyst for Aerobic Oxidation of Benzylic Amines to Imines and N-Substituted 1,2,3,4-Tetrahydroisoquinolines to Amides: Synthetic Applications and Mechanistic Study

So, Man-Ho; et al, Chemistry - An Asian Journal, 2009, 4(10), 1551-1561

Production Method 27

64-10-8

105-13-5

836-41-9

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Oxygen ;  24 h, 135 °C

Reference

Base-mediated synthesis of imines and amines from N-phenylureas and alcohols

Yadav, Dilip Kumar T.; et al, Synlett, 2014, 25(11), 1611-1615

Production Method 28

3585-93-1

836-41-9

Reaction Conditions

1.1 Reagents: Indium ,  Ammonium chloride Solvents: Methanol

Reference

Indium-mediated deoxygenation of nitrones, N-oxides and deoxygenative reductive coupling of nitrones to vicinal diamines

Jeevanandam, Arumugasamy; et al, Synthetic Communications, 2000, 30(17), 3153-3160

Production Method 29

3585-93-1

836-41-9

Reaction Conditions

1.1 Reagents: Triphenylphosphine ,  Iodine Solvents: Benzene

Reference

Deoxygenation of α-aryl-N-phenylnitrones with diiodotriphenylphosphorane

Furukawa, Isao; et al, Nippon Kagaku Kaishi, 1989, (10), 1748-52

Production Method 30

103-33-3

105-13-5

836-41-9

Reaction Conditions

1.1 Reagents: Potassium carbonate Catalysts: 2923249-07-2 Solvents: Toluene ;  20 h, 130 °C

Reference

Chemodivergent coupling of azoarenes with benzyl alcohols via a borrowing hydrogen strategy using a well-defined nickel catalyst

Bansal, Sadhna; et al, Catalysis Science & Technology, 2023, 13(9), 2705-2713

Production Method 31

123-11-5

622-37-7

836-41-9

Reaction Conditions

1.1 Reagents: Triphenylphosphine Catalysts: Methyltrioxorhenium Solvents: Benzene ;  10 min, rt
1.2 2 h, rt

Reference

Organic Reactions Catalyzed by Methylrhenium Trioxide: Reactions of Ethyl Diazoacetate and Organic Azides

Zhu, Zuolin; et al, Journal of the American Chemical Society, 1996, 118(41), 9901-9907

Production Method 32

64-10-8

959-33-1

836-41-9

Reaction Conditions

1.1 Catalysts: Potassium hydroxide ;  24 h, 135 °C

Reference

Base-catalyzed synthesis of amides and imines via C-C and C=C bond cleavage

Yadav, Dilip Kumar T.; et al, RSC Advances, 2015, 5(16), 12387-12391

Production Method 33

32979-94-5

836-41-9

Reaction Conditions

1.1 Reagents: Boron trifluoride etherate ,  Oxygen Solvents: Acetonitrile-d3

Reference

Oxidative carbon-carbon bond cleavage reaction of 1,2-diamines and 1,2-amino alcohols under an oxygen atmosphere

Shimizu, Makoto; et al, Tetrahedron Letters, 2001, 42(50), 8865-8868

Production Method 34

38968-72-8

836-41-9

Reaction Conditions

1.1 Catalysts: Acetic acid

Reference

A simple high yield conversion of imidoyl chlorides to imines and amines

Alper, Howard; et al, Synthesis, 1978, (10), 781-2

Production Method 35

45821-44-1

836-41-9

Reaction Conditions

1.1 Solvents: Ethanol ;  overnight, rt

Reference

N-Heterocyclic carbene (NHC)-catalyzed oxidation of unactivated aldimines to amides via imine umpolung under aerobic conditions

Ramarao, Jakkula; et al, RSC Advances, 2022, 12(13), 7621-7625

1-(4-methoxyphenyl)-N-phenyl-methanimine Raw materials

• (4-methoxyphenyl)methanamine
• phenylurea
• 4-Methoxychalcone
• Azobenzene
• 1,2-Ethanediamine, 1,2-bis(4-methoxyphenyl)-N1,N2-diphenyl-, (1R,2S)-rel-
• 1,3,2-DIOXABOROLAN-2-AMINE, 4,4,5,5-TETRAMETHYL-N-PHENYL-
• 4-Methylbenzaldehyde
• 4-Methoxybenzyl alcohol
• benzenamine, n-[(4-methoxyphenyl)methylene]-, n-oxide
• Benzenecarboximidoyl chloride, 4-methoxy-N-phenyl-
• p-Methoxybenzaldehyde
• Benzaldehyde
• azidobenzene
• N-[(4-methoxyphenyl)methyl]aniline

1-(4-methoxyphenyl)-N-phenyl-methanimine Preparation Products

• 1-(4-methoxyphenyl)-N-phenyl-methanimine (836-41-9)

• 1. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 2. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 3. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 4. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 5. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291

• 145771-82-0(Phenol, 4-[[(4-methoxyphenyl)imino]methyl]-, (E)-)
• 3246-78-4(N-[(E)-(4-methoxyphenyl)methylidene]-4-methylaniline)
• 3525-51-7(N-(4-methoxyphenyl)-1-[4-[(4-methoxyphenyl)iminomethyl]phenyl]methanimine)
• 1749-08-2(N,1-Bis(4-Methoxyphenyl)Methanimine)
• 5877-59-8(Benzenamine, 3-methoxy-N-(phenylmethylene)-)
• 783-08-4(N-Benzylidene-4-methoxyaniline)
• 3230-39-5(p-Methoxybenzylidene p-aminophenol)
• 24998-39-8(Phenol,3-[[(4-methoxyphenyl)methylene]amino]-)
• 1613-90-7(Benzenamine, 4-methoxy-N-(phenylmethylene)-, (E)-)
• 116807-88-6(1,4-Benzenediamine, N-[(4-methoxyphenyl)methylene]-)