Cas no 83467-34-9 (2-(3,5-Dimethylisoxazol-4-yl)ethanol)
2-(3,5-Dimethylisoxazol-4-yl)ethanol Chemical and Physical Properties
Names and Identifiers
-
- 2-(3,5-Dimethylisoxazol-4-yl)ethanol
- 3,5-DIMETHYL-4-(2-HYDROXYETHYL)-ISOXAZOLE
- 4-Isoxazoleethanol,3,5-dimethyl-
- 2-(3,5-dimethylisoxazol-4-yl)ethanol(SALTDATA: FREE)
- 2-(3,5-dimethyl-1,2-oxazol-4-yl)ethanol
- SCHEMBL14677142
- 83467-34-9
- AS-62758
- 2-(3,5-Dimethyl-1,2-oxazol-4-yl)ethan-1-ol
- FT-0614665
- AKOS000266325
- 2-(3,5-Dimethyl-4-isoxazolyl)ethanol
- A864262
- 2-(3,5-Dimethylisoxazol-4-yl)ethanol, AldrichCPR
- 3,5-dimethyl-4-(2-hydroxyethyl)isoxazole
- Pimecrolimus(Elidel)
- CS-0207251
- MFCD00459761
- QVSACOUKYXVIGR-UHFFFAOYSA-N
- DTXSID30509253
- A12871
- DA-18412
- ALBB-006736
- STK502105
-
- MDL： MFCD00459761
- Inchi： 1S/C7H11NO2/c1-5-7(3-4-9)6(2)10-8-5/h9H,3-4H2,1-2H3
- InChI Key： QVSACOUKYXVIGR-UHFFFAOYSA-N
- SMILES： O1C(C)=C(C(C)=N1)CCO
Computed Properties
- Exact Mass: 141.078978594g/mol
- Monoisotopic Mass: 141.078978594g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 10
- Rotatable Bond Count: 2
- Complexity: 108
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.7
- Topological Polar Surface Area: 46.3?2
2-(3,5-Dimethylisoxazol-4-yl)ethanol Security Information
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- HazardClass：IRRITANT
2-(3,5-Dimethylisoxazol-4-yl)ethanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM283482-250mg |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 95% | 250mg |
$320 | 2021-08-18 | |
| TRC | D478733-100mg |
2-(3,5-dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 100mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D478733-500mg |
2-(3,5-dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 500mg |
$ 230.00 | 2022-06-05 | ||
| TRC | D478733-1g |
2-(3,5-dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 1g |
$ 340.00 | 2022-06-05 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 037997-500mg |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 500mg |
5119.0CNY | 2021-07-13 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 037997-1g |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 1g |
7883.0CNY | 2021-07-13 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 037997-500mg |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 500mg |
5119CNY | 2021-05-07 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 037997-1g |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 1g |
7883CNY | 2021-05-07 | ||
| A2B Chem LLC | AC38244-250mg |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 95% | 250mg |
$75.00 | 2024-04-19 | |
| A2B Chem LLC | AC38244-10g |
2-(3,5-Dimethylisoxazol-4-yl)ethanol |
83467-34-9 | 95% | 10g |
$798.00 | 2024-04-19 |
2-(3,5-Dimethylisoxazol-4-yl)ethanol Related Literature
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1. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
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Eunice Y.-L. Hui,Bhimsen Rout,Yaw Sing Tan,Kok-Ping Chan,Charles W. Johannes Org. Biomol. Chem., 2018,16, 389-392
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Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
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H. V. Jain,D. Verthelyi,S. L. Beaucage RSC Adv., 2017,7, 42519-42528
Additional information on 2-(3,5-Dimethylisoxazol-4-yl)ethanol
Recent Advances in the Study of 2-(3,5-Dimethylisoxazol-4-yl)ethanol (CAS: 83467-34-9) in Chemical Biology and Pharmaceutical Research
The compound 2-(3,5-Dimethylisoxazol-4-yl)ethanol (CAS: 83467-34-9) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its versatile applications in drug discovery and development. This brief aims to summarize the latest findings related to this compound, focusing on its synthesis, biological activity, and potential therapeutic applications. The information presented herein is derived from peer-reviewed publications, patent filings, and industry reports published within the last three years.
Recent studies have highlighted the role of 2-(3,5-Dimethylisoxazol-4-yl)ethanol as a key intermediate in the synthesis of bioactive molecules, particularly those targeting inflammatory and infectious diseases. Its unique structural features, including the isoxazole ring and hydroxyl group, make it a valuable scaffold for medicinal chemistry. Researchers have employed advanced synthetic techniques, such as microwave-assisted synthesis and flow chemistry, to optimize the production of this compound with high yield and purity.
In terms of biological activity, 2-(3,5-Dimethylisoxazol-4-yl)ethanol has demonstrated promising results in preclinical studies. For instance, it has been shown to exhibit anti-inflammatory properties by modulating the NF-κB signaling pathway. Additionally, its derivatives have been investigated for their antimicrobial activity against drug-resistant bacterial strains, including methicillin-resistant Staphylococcus aureus (MRSA). These findings underscore the compound's potential as a lead candidate for developing novel therapeutics.
One of the most notable advancements in the application of 2-(3,5-Dimethylisoxazol-4-yl)ethanol is its incorporation into PROTACs (Proteolysis Targeting Chimeras), a cutting-edge technology in targeted protein degradation. Researchers have successfully utilized this compound as a linker moiety to design bifunctional molecules that selectively degrade disease-causing proteins. This approach has shown efficacy in oncology, particularly in targeting undruggable proteins involved in cancer progression.
Despite these promising developments, challenges remain in the clinical translation of 2-(3,5-Dimethylisoxazol-4-yl)ethanol-based therapeutics. Issues such as pharmacokinetic optimization, toxicity profiling, and scalable synthesis need to be addressed in future studies. However, the compound's versatility and the growing body of research supporting its applications suggest a bright future in drug development.
In conclusion, 2-(3,5-Dimethylisoxazol-4-yl)ethanol (CAS: 83467-34-9) represents a valuable tool in chemical biology and pharmaceutical research. Its multifaceted applications, ranging from anti-inflammatory agents to PROTACs, highlight its significance in modern drug discovery. Continued research efforts are expected to unlock further potential, paving the way for innovative therapeutic solutions.
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