Cas no 832737-37-8 (2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine)

2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine structure
832737-37-8 structure
Product Name:2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine
CAS No:832737-37-8
MF:C14H13F3N2O2S
MW:330.325432538986
MDL:MFCD05667118
CID:3059656
PubChem ID:17024560
Update Time:2025-11-02

2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine Chemical and Physical Properties

Names and Identifiers

    • 2-(Ethylsulfonyl)-4-(p-tolyl)-6-(trifluoromethyl)pyrimidine
    • 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine
    • AKOS000311440
    • 2-ethylsulfonyl-4-(p-tolyl)-6-(trifluoromethyl)pyrimidine
    • 2-ethylsulfonyl-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine
    • BBL038537
    • EN300-229980
    • 2-Ethanesulfonyl-4-p-tolyl-6-trifluoromethyl-pyrimidine
    • 832737-37-8
    • STK312214
    • 2-(ethylsulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine
    • CS-0299635
    • MDL: MFCD05667118
    • Inchi: 1S/C14H13F3N2O2S/c1-3-22(20,21)13-18-11(8-12(19-13)14(15,16)17)10-6-4-9(2)5-7-10/h4-8H,3H2,1-2H3
    • InChI Key: TYQHISYWSLUYCN-UHFFFAOYSA-N
    • SMILES: S(C1N=C(C(F)(F)F)C=C(C2C=CC(C)=CC=2)N=1)(CC)(=O)=O

Computed Properties

  • Exact Mass: 330.06498332Da
  • Monoisotopic Mass: 330.06498332Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 22
  • Rotatable Bond Count: 4
  • Complexity: 467
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 68.3?2

2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine Pricemore >>

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Additional information on 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine

Comprehensive Overview of 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine (CAS No. 832737-37-8)

2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine (CAS No. 832737-37-8) is a specialized pyrimidine derivative with significant applications in pharmaceutical and agrochemical research. This compound features a unique molecular structure, combining an ethanesulfonyl group, a 4-methylphenyl moiety, and a trifluoromethyl substituent, which contribute to its distinct chemical properties and reactivity. Researchers and industry professionals are increasingly interested in this compound due to its potential as a building block for drug discovery and material science.

The growing demand for trifluoromethylated compounds in modern chemistry has placed 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine in the spotlight. Its CAS No. 832737-37-8 is frequently searched in academic databases and chemical marketplaces, reflecting its relevance in high-value synthetic applications. The compound’s sulfonyl group enhances its stability and solubility, making it a versatile intermediate for heterocyclic chemistry and medicinal chemistry projects.

In recent years, the pharmaceutical industry has shown heightened interest in pyrimidine-based scaffolds due to their role in designing kinase inhibitors and antiviral agents. The presence of the trifluoromethyl group in CAS No. 832737-37-8 is particularly noteworthy, as it often improves metabolic stability and bioavailability in drug candidates. This aligns with current trends in precision medicine and targeted therapy, where researchers seek compounds with optimized pharmacokinetic profiles.

From a synthetic chemistry perspective, 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine offers multiple sites for further functionalization. The 4-methylphenyl ring can undergo electrophilic aromatic substitution, while the pyrimidine core is amenable to nucleophilic attacks. Such flexibility makes it a valuable intermediate for constructing complex molecules, including agrochemicals and specialty chemicals. Its CAS No. 832737-37-8 is often cited in patents and research papers focusing on crop protection and sustainable agriculture.

Another area of interest is the compound’s potential in material science. The trifluoromethyl group imparts lipophilicity and electron-withdrawing characteristics, which are desirable in designing organic electronic materials and liquid crystals. As industries explore green chemistry and energy-efficient processes, 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine could play a role in developing next-generation functional materials.

For researchers sourcing CAS No. 832737-37-8, quality and purity are critical factors. Reputable suppliers provide detailed analytical data, including HPLC, NMR, and mass spectrometry results, to ensure compliance with Good Laboratory Practices (GLP). The compound’s stability under various storage conditions is also a common query, emphasizing the need for proper handling and storage protocols.

In summary, 2-(ethanesulfonyl)-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine (CAS No. 832737-37-8) is a multifaceted compound with broad applicability in drug development, agrochemical innovation, and advanced materials. Its structural features align with contemporary research priorities, making it a subject of ongoing scientific exploration. As the demand for tailor-made chemicals grows, this compound is poised to remain a key player in cutting-edge chemistry.

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