Production Method 1

344-07-0

832-53-1

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  -20 °C
2.1 Reagents: Sulfur dioxide ,  Chlorine Solvents: Tetrahydrofuran ;  -78 °C; 0 °C

Reference

Chloropentafluorobenzene

Anilkumar, R.; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2005, 1, 1-5

Production Method 2

879-06-1

832-53-1

Reaction Conditions

1.1 Reagents: Sulfur dioxide ,  Chlorine Solvents: Tetrahydrofuran ;  -78 °C → 0 °C

Reference

1-Chloro-2,3,4,5,6-pentafluorobenzene (CPFB)

Anilkumar, R.; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, ,

Production Method 3

363-72-4

832-53-1

Reaction Conditions

1.1 Reagents: Chlorosulfonic acid ;  3 h, 150 °C

Reference

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia

Toutah, Krimo; et al, Journal of Medicinal Chemistry, 2021, 64(12), 8486-8509

Production Method 4

778-36-9

832-53-1

Reaction Conditions

1.1 Reagents: Thionyl chloride

Reference

Sulfur-nitrogen compounds. VII. Preparation and reactions of some perfluoro aromatic sulfur-nitrogen compounds

Glander, I.; et al, Journal of Fluorine Chemistry, 1979, 14(5), 403-20

Production Method 5

1306747-56-7

832-53-1

344-07-0

344-04-7

363-72-4

Reaction Conditions

1.1 25 h, 145 - 155 °C
2.1 Reagents: Sodium chloride Solvents: Acetonitrile ;  rt; 22 h, rt

Reference

Transformations of polyfluoroarenesulfonyl halides with alkenes, polyfluoroarenethiols and alkali metal halides

Bredikhin, Roman A.; et al, International Electronic Conference on Synthetic Organic Chemistry, 2011, ,

Production Method 6

344-07-0

832-53-1

Reaction Conditions

1.1 Reagents: Magnesium ,  Sulfur dioxide Solvents: Tetrahydrofuran
1.2 Reagents: Chlorine Solvents: Tetrahydrofuran

Reference

Perfluoro- and polyfluorosulfonic acids. Part 22. Polyfluorophenyl pentafluorobenzenesulfonates and their electron-transfer reaction with sodium iodide

Chen, Qing Yun; et al, Journal of the Chemical Society, 1991, (7), 1071-5

Production Method 7

879-06-1

832-53-1

Reaction Conditions

1.1 Reagents: Sulfur dioxide ,  Chlorine Solvents: Tetrahydrofuran ;  -78 °C; 0 °C

Reference

Chloropentafluorobenzene

Anilkumar, R.; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2005, 1, 1-5

Production Method 8

832-53-1

Reaction Conditions

1.1 Reagents: Potassium fluoride
2.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  -20 °C
3.1 Reagents: Sulfur dioxide ,  Chlorine Solvents: Tetrahydrofuran ;  -78 °C; 0 °C

Reference

Chloropentafluorobenzene

Anilkumar, R.; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2005, 1, 1-5

Production Method 9

140200-30-2

832-53-1

344-07-0

344-04-7

363-72-4

Reaction Conditions

1.1 Reagents: Sodium chloride Solvents: Acetonitrile ;  rt; 22 h, rt

Reference

Transformations of polyfluoroarenesulfonyl halides with alkenes, polyfluoroarenethiols and alkali metal halides

Bredikhin, Roman A.; et al, International Electronic Conference on Synthetic Organic Chemistry, 2011, ,

Production Method 10

776-09-0

832-53-1

344-07-0

344-04-7

363-72-4

Reaction Conditions

1.1 Reagents: Sodium bromide Solvents: Acetonitrile ;  rt; 19 h, rt
2.1 Reagents: Sodium chloride Solvents: Acetonitrile ;  rt; 22 h, rt

Reference

Transformations of polyfluoroarenesulfonyl halides with alkenes, polyfluoroarenethiols and alkali metal halides

Bredikhin, Roman A.; et al, International Electronic Conference on Synthetic Organic Chemistry, 2011, ,

Production Method 11

832-53-1

832-53-1

344-07-0

344-04-7

363-72-4

Reaction Conditions

1.1 Catalysts: Cuprous iodide ;  3 h, 149 - 154 °C
2.1 25 h, 145 - 155 °C
3.1 Reagents: Sodium chloride Solvents: Acetonitrile ;  rt; 22 h, rt

Reference

Transformations of polyfluoroarenesulfonyl halides with alkenes, polyfluoroarenethiols and alkali metal halides

Bredikhin, Roman A.; et al, International Electronic Conference on Synthetic Organic Chemistry, 2011, ,

2,3,4,5,6-pentafluorobenzenesulfonyl chloride Raw materials

• Chloropentafluorobenzene
• 2,3,5,6-Tetrafluorobenzene-1-sulfonyl Chloride
• 2,3,4,5,6-pentafluorobenzenesulfonyl chloride
• 1,2,3,4,5-Pentafluoro-6-(2-propen-1-ylsulfonyl)benzene
• Benzenesulfonyl bromide, pentafluoro-
• 1,2,3,4,5-pentafluorobenzene
• Magnesium,chloro(2,3,4,5,6-pentafluorophenyl)-
• pentafluorobenzene-1-sulfonamide

2,3,4,5,6-pentafluorobenzenesulfonyl chloride Preparation Products

• Chloropentafluorobenzene (344-07-0)
• 2,3,4,5,6-pentafluorobenzenesulfonyl chloride (832-53-1)
• Bromopentafluorobenzene (344-04-7)
• 1,2,3,4,5-pentafluorobenzene (363-72-4)

• 1. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
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• 2. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
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  Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
• 4. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 5. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzenesulfonyl compounds Benzenesulfonyl halides
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

• 210532-25-5(3,5-Difluorobenzenesulfonyl chloride)
• 60230-36-6(2,6-difluorobenzene-1-sulfonyl chloride)
• 13918-92-8(2,4-Difluorobenzenesulfonyl chloride)
• 26120-86-5(2,5-difluorobenzene-1-sulfonyl chloride)
• 175278-08-7(2,3,4-trifluorobenzene-1-sulfonyl chloride)
• 2905-21-7(2-Fluorobenzenesulphonyl chloride)
• 701-27-9(3-Fluorobenzenesulfonyl chloride)
• 351003-43-5(3,4,5-Trifluorobenzene-1-sulfonyl chloride)
• 220227-21-4(2,4,5-trifluorobenzene-1-sulfonyl chloride)
• 145758-05-0(3,4-Difluorobenzenesulfonyl chloride)