Cas no 827-45-2 (2-Phenyl-1,3-thiazol-4-ol)

2-Phenyl-1,3-thiazol-4-ol is a heterocyclic compound featuring a thiazole core substituted with a phenyl group at the 2-position and a hydroxyl group at the 4-position. This structure imparts unique reactivity and versatility, making it valuable in organic synthesis and pharmaceutical applications. The compound serves as a key intermediate in the preparation of biologically active molecules, including potential antimicrobial and anti-inflammatory agents. Its aromatic and heterocyclic properties contribute to stability and functional group compatibility, facilitating further derivatization. The hydroxyl group enhances solubility and provides a reactive site for modifications, while the phenyl group influences electronic and steric properties. Suitable for research and industrial use, it offers a balance of synthetic utility and structural diversity.
2-Phenyl-1,3-thiazol-4-ol structure
2-Phenyl-1,3-thiazol-4-ol structure
Product Name:2-Phenyl-1,3-thiazol-4-ol
CAS No:827-45-2
MF:C9H7NOS
MW:177.222980737686
MDL:MFCD08444022
CID:707131
PubChem ID:568728
Update Time:2025-05-28

2-Phenyl-1,3-thiazol-4-ol Chemical and Physical Properties

Names and Identifiers

    • 4-Thiazolol, 2-phenyl-
    • 2-Phenyl-1,3-thiazol-4-ol
    • 4-HYDROXY-2-PHENYL-1,3-THIAZOLE
    • 2-phenyl-thiazol-4-one
    • 4-Thiazolol,2-phenyl
    • hydroxyphenylthiazole
    • phenylthiazolol
    • 2-Phenyl-4-thiazolol (ACI)
    • 2-phenyl-1,3-thiazol-4-ol, AldrichCPR
    • CCMLIFHRMDXEBM-UHFFFAOYSA-N
    • 2-Phenylthiazol-4-ol
    • 827-45-2
    • MFCD08444022
    • EA-0700
    • DTXSID10340949
    • CS-0322388
    • J-510272
    • AKOS005072400
    • 2-Phenyl-1,3-thiazol-4-ol #
    • SCHEMBL242692
    • MDL： MFCD08444022
    • Inchi： 1S/C9H7NOS/c11-8-6-12-9(10-8)7-4-2-1-3-5-7/h1-6,11H
    • InChI Key： CCMLIFHRMDXEBM-UHFFFAOYSA-N
    • SMILES： OC1=CSC(C2C=CC=CC=2)=N1

Computed Properties

  • Exact Mass: 177.02500
  • Monoisotopic Mass: 177.02483502g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 148
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.6
  • Topological Polar Surface Area: 61.4?2

Experimental Properties

  • Melting Point: 119-121°C
  • PSA: 61.36000
  • LogP: 2.51570

2-Phenyl-1,3-thiazol-4-ol Security Information

  • Hazard Category Code： 22
  • Hazardous Material Identification： Xi
  • HazardClass：IRRITANT

2-Phenyl-1,3-thiazol-4-ol Customs Data

  • HS CODE：2934100090
  • Customs Data：

    China Customs Code:

    2934100090

    Overview:

    2934100090. Compounds that structurally contain a non fused thiazole ring(Whether hydrogenated or not). VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-Phenyl-1,3-thiazol-4-ol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A059006342-5g
2-Phenylthiazol-4-ol
 827-45-2 95%
5g
 $852.60 2023-09-01
Apollo Scientific
OR15120-50mg
2-Phenyl-1,3-thiazol-4-ol
 827-45-2
50mg
 ￡20.00 2025-02-19
TRC
P400283-2.5mg
2-Phenyl-1,3-thiazol-4-ol
 827-45-2
2.5mg
 $ 50.00 2022-06-03
TRC
P400283-5mg
2-Phenyl-1,3-thiazol-4-ol
 827-45-2
5mg
 $ 65.00 2022-06-03
TRC
P400283-25mg
2-Phenyl-1,3-thiazol-4-ol
 827-45-2
25mg
 $ 95.00 2022-06-03
SHANG HAI XIAN DING Biotechnology Co., Ltd.
046145-500mg
2-Phenyl-1,3-thiazol-4-ol
 827-45-2 >95%
500mg
 3396.0CNY 2021-07-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.
046145-500mg
2-Phenyl-1,3-thiazol-4-ol
 827-45-2 >95%
500mg
 3396CNY 2021-05-07
Chemenu
CM525846-1g
2-Phenylthiazol-4-ol
 827-45-2 95%
1g
 $268 2023-01-04
eNovation Chemicals LLC
D123731-5g
2-PHENYL-1,3-THIAZOL-4-OL
 827-45-2 95%
5g
 $1450 2025-02-21
eNovation Chemicals LLC
D123731-10g
2-PHENYL-1,3-THIAZOL-4-OL
 827-45-2 95%
10g
 $1980 2025-02-21

2-Phenyl-1,3-thiazol-4-ol Production Method

Production Method 1

Reaction Conditions
Reference
The Vilsmeier reaction of fully conjugated carbocycles and heterocycles
Jones, Gurnos; et al, Organic Reactions (Hoboken, 1997, 49,

Production Method 2

Reaction Conditions
Reference
Product class 17: thiazoles
Kikelj, D.; et al, Science of Synthesis, 2002, 11, 627-833

2-Phenyl-1,3-thiazol-4-ol Raw materials

2-Phenyl-1,3-thiazol-4-ol Preparation Products

2-Phenyl-1,3-thiazol-4-ol Related Literature

827-45-2 (2-Phenyl-1,3-thiazol-4-ol) Related Products

Recommended suppliers
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
上海帛亦醫(yī)藥科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Shanghai Bent Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
SunaTech Inc.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
SunaTech Inc.