Production Method 1

875-51-4

827-23-6

Reaction Conditions

1.1 Reagents: Bromine Solvents: Carbon tetrachloride ;  20 - 25 °C; 1 h, rt

Reference

Effect of structural factors and solvent nature in bromination of anilines

Bagmanov, B. T., Russian Journal of Applied Chemistry, 2009, 82(9), 1570-1576

Production Method 2

827-23-6

Reaction Conditions

1.1 Reagents: Bromine Solvents: Methanol ,  Dichloromethane ;  1 h, rt

Reference

New synthesis of (±)-cis-trikentrin A via tandem indole aryne cycloaddition/Negishi reaction. Applications to library development

Brown, Neil; et al, Tetrahedron Letters, 2009, 50(51), 7113-7115

Production Method 3

827-23-6

Reaction Conditions

1.1 Reagents: Sodium bromide ,  Sodium bromate Solvents: Dichloromethane ,  Water ;  2 h, 25 - 40 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  60 min, rt; 40 - 60 min, rt

Reference

Eco-friendly and versatile brominating reagent prepared from a liquid bromine precursor

Adimurthy, Subbarayappa; et al, Green Chemistry, 2006, 8(10), 916-922

Production Method 4

875-51-4

827-23-6

Reaction Conditions

1.1 Reagents: Bromine Solvents: Carbon tetrachloride ;  cooled; 20 - 25 °C; 1 h, rt

Reference

Features of molecular bromination of aromatic amines

Salahov, M. S.; et al, Azerbaidzhanskii Khimicheskii Zhurnal, 2014, (3), 22-27

Production Method 5

827-23-6

Reaction Conditions

1.1 Reagents: 2,3,5,6-Tetrabromo-4-methyl-4-nitro-2,5-cyclohexadien-1-one Solvents: Trifluoroacetic acid

Reference

Direct nitration of anilines using nitrocyclohexadienones

Lemaire, M.; et al, Synthesis, 1989, (10), 761-3

Production Method 6

616-84-2

827-23-6

Reaction Conditions

1.1 Solvents: Water

Reference

Halogenation. XX. The replacement of sulfonic acid groups by halogens

Datta, Rasik Lal; et al, Journal of the American Chemical Society, 1921, 43, 303-15

Production Method 7

827-23-6

875-51-4

Reaction Conditions

1.1 Catalysts: Copper sulfate Solvents: Acetonitrile ,  Water ;  15 min, 25 °C
1.2 Reagents: Sodium bromide ,  Sodium persulfate ;  15 min, 7 °C; 2 h, 7 °C; 22 h, 25 °C
1.3 Reagents: Sodium hydroxide ,  Sodium thiosulfate Solvents: Water ;  pH 9

Reference

A Practical Procedure for Regioselective Bromination of Anilines

Takahashi, Yusuke; et al, Synthesis, 2021, 53(10), 1828-1832

Production Method 8

827-23-6

875-51-4

Reaction Conditions

1.1 Reagents: Hydrogen tribromide, compd. with N,N-dimethylacetamide (1:2) Solvents: Ethanol ,  Water

Reference

Bis(dimethylacetamide)hydrogen dibromobromate: new brominating agent

Rodygin, M. Yu.; et al, Zhurnal Organicheskoi Khimii, 1992, 28(9), 1926-7

Production Method 9

827-23-6

875-51-4

Reaction Conditions

1.1 Reagents: Ammonium bromide ,  Potassium peroxymonosulfate sulfate (2KHSO5.KHSO4.K2SO4) Solvents: Methanol ,  Water ;  4 min, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water ;  rt

Reference

Fast and efficient bromination of aromatic compounds with ammonium bromide and oxone

Naresh, Mameda; et al, Synthesis, 2013, 45(11), 1497-1504

Production Method 10

29530-42-5

827-23-6

875-51-4

14227-18-0

Reaction Conditions

1.1 Reagents: Hydrogen bromide Solvents: Acetic acid ,  Water

Reference

Preparation of some 2-(methoxyphenyl)-2H-benzotriazoles and the corresponding hydroxyphenyl compounds

Rosevear, Judi; et al, Australian Journal of Chemistry, 1987, 40(10), 1663-73

Production Method 11

612-29-3

827-23-6

875-51-4

14227-18-0

Reaction Conditions

1.1 Solvents: Acetic acid
2.1 Reagents: Hydrogen bromide Solvents: Acetic acid ,  Water

Reference

Preparation of some 2-(methoxyphenyl)-2H-benzotriazoles and the corresponding hydroxyphenyl compounds

Rosevear, Judi; et al, Australian Journal of Chemistry, 1987, 40(10), 1663-73

2,4-Dibromo-6-nitroaniline Raw materials

• 4-Bromo-2-nitroaniline
• 2-Nitroaniline-4-sulfonic acid
• Diazene, (3-methoxyphenyl)(2-nitrophenyl)-
• 1-nitro-2-nitrosobenzene

2,4-Dibromo-6-nitroaniline Preparation Products

• 4-Bromo-2-nitroaniline (875-51-4)
• 2,4-Dibromo-6-nitroaniline (827-23-6)
• 1,3,5-Trimethoxy-2-nitrobenzene (14227-18-0)

• 1. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 2. Excimer formation effects and trap-assisted charge recombination loss channels in organic solar cells of perylene diimide dimer acceptors?
  Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
• 3. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 4. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 5. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes

• 1817-73-8(2-Bromo-4,6-dinitro-benzenamine)
• 13296-94-1(2-Bromo-4-nitroaniline)
• 63240-26-6(2-Bromo-4-Nitro-Naphthalen-1-Ylamine)
• 5228-61-5(5-Bromo-2-nitroaniline)
• 827-94-1(2,6-Dibromo-4-nitroaniline)
• 62554-90-9(4-Bromo-2,6-dinitroaniline)
• 875-51-4(4-Bromo-2-nitroaniline)
• 59255-95-7(2-Bromo-6-nitroaniline)
• 7138-15-0(3-Bromo-2-nitroaniline)
• 147021-89-4(4-bromo-3-nitro-benzene-1,2-diamine)