Production Method 1

70671-46-4

82044-23-3

Reaction Conditions

1.1 Reagents: Potassium hydroxide Solvents: Ethanol ;  1.5 h, -20 °C; -20 °C → 0 °C; 17 h, 0 °C
1.2 Solvents: Ethanol ,  Water ;  30 min, rt → reflux

Reference

Total Synthesis of Solandelactone I

Eichenauer, Nils C.; et al, Journal of Natural Products, 2015, 78(11), 2782-2790

Production Method 2

134267-57-5

82044-23-3

Reaction Conditions

1.1 Reagents: Potassium hydroxide Solvents: Ethanol

Reference

Enantioselective synthesis of 2-alkyl-5-methylene-1,3-dioxolan-4-ones and exo-selective Diels-Alder reactions with cyclopentadiene

Roush, William R.; et al, Journal of Organic Chemistry, 1992, 57(12), 3380-7

Production Method 3

56-45-1

82044-23-3

Reaction Conditions

1.1 Reagents: Potassium bromide ,  Hydrogen bromide Solvents: Water ;  rt → -10 °C
1.2 Reagents: Sodium nitrite ;  -10 °C; -10 °C → 0 °C; 12 h, 0 °C
1.3 Reagents: Potassium hydroxide Solvents: Ethanol ;  -15 °C; 2 h, -15 °C; -15 °C → 0 °C; 16 h, 0 °C; pH 2 - 3

Reference

The asymmetric total synthesis of (+)-salvianolic acid A

Zheng, Yong; et al, Tetrahedron, 2016, 72(33), 5047-5050

Production Method 4

56-45-1

82044-23-3

Reaction Conditions

1.1 Reagents: Potassium bromide ,  Nitrous acid Solvents: Water
1.2 Reagents: Potassium hydroxide Solvents: Ethanol

Reference

Potent Inhibitors of a Shikimate Pathway Enzyme from Mycobacterium tuberculosis: Combining mechanism- and modeling-based design

Reichau, Sebastian; et al, Journal of Biological Chemistry, 2011, 286(18), 16197-16207

Production Method 5

56-45-1

82044-23-3

Reaction Conditions

Reference

Total Synthesis of Berkeleylactone A

Ferko, Branislav; et al, Journal of Organic Chemistry, 2019, 84(11), 7159-7165

Production Method 6

111058-32-3

82044-23-3

Reaction Conditions

1.1 Reagents: Potassium hydroxide Solvents: Methanol ;  0 °C → rt; 16 h, rt

Reference

Synthesis of the fungal macrolide berkeleylactone A and its inhibition of microbial biofilm formation

Schriefer, Manuel G.; et al, Organic & Biomolecular Chemistry, 2021, 19(21), 4743-4751

Production Method 7

4538-50-5

82044-23-3

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: p-Toluenesulfonic acid ,  (SP-4-2)-[[2,2′-[(1S,2S)-1,2-Cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6… Solvents: Dichloromethane ;  1 h, rt
1.2 Solvents: Water ;  21 h, rt; 2 h, 85 °C
2.1 Reagents: Potassium hydroxide Solvents: Methanol ;  0 °C → rt; 16 h, rt

Reference

Synthesis of the fungal macrolide berkeleylactone A and its inhibition of microbial biofilm formation

Schriefer, Manuel G.; et al, Organic & Biomolecular Chemistry, 2021, 19(21), 4743-4751

Production Method 8

82044-23-3

Reaction Conditions

1.1 Reagents: Sodium hypochlorite ;  30 min, 0 °C; 1.5 h, > 0 °C
2.1 Reagents: Oxygen Catalysts: p-Toluenesulfonic acid ,  (SP-4-2)-[[2,2′-[(1S,2S)-1,2-Cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6… Solvents: Dichloromethane ;  1 h, rt
2.2 Solvents: Water ;  21 h, rt; 2 h, 85 °C
3.1 Reagents: Potassium hydroxide Solvents: Methanol ;  0 °C → rt; 16 h, rt

Reference

Synthesis of the fungal macrolide berkeleylactone A and its inhibition of microbial biofilm formation

Schriefer, Manuel G.; et al, Organic & Biomolecular Chemistry, 2021, 19(21), 4743-4751

Potassium (R)-Glycidate Raw materials

• L-Serine
• methyl (2R)-oxirane-2-carboxylate
• methyl oxirane-2-carboxylate
• Propanoic acid, 2-chloro-3-hydroxy-, (-)-
• (2S)-2-Bromo-3-hydroxypropanoic acid

Potassium (R)-Glycidate Preparation Products

• Potassium (R)-Glycidate (82044-23-3)

• 1. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 2. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 3. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 4. Excited state potential energy surfaces and their interactions in FeIVO active sites
  Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
• 5. Distribution pattern and allocation of defects in hydrogenated ZnO thin films?
  Vitaly Gurylev,Chung-Yi Su,Tsong-Pyng Perng Phys. Chem. Chem. Phys., 2016,18, 16033-16038

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Epoxides Oxirane carboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Epoxides Oxirane carboxylic acids and derivatives Oxirane carboxylic acids

Potassium (R)-Glycidate: A Comprehensive Overview

Potassium (R)-Glycidate, identified by the CAS number 82044-23-3, is a significant compound in the field of organic chemistry and materials science. This compound, also referred to as potassium (R)-glycidate, has garnered attention due to its unique properties and versatile applications. The compound is characterized by its glycidic acid derivative structure, which imparts it with distinctive chemical and physical attributes.

The synthesis of Potassium (R)-Glycidate involves a series of carefully controlled reactions, often leveraging advanced techniques such as enantioselective catalysis. Recent studies have highlighted the potential of this compound in the development of novel materials, particularly in the realm of biodegradable polymers. Researchers have demonstrated that Potassium (R)-Glycidate can serve as a building block for creating polymers with tailored mechanical properties, making it a valuable asset in sustainable materials science.

In terms of applications, Potassium (R)-Glycidate has found utility in various industries, including pharmaceuticals and agriculture. Its role as an intermediate in drug synthesis has been well-documented, with recent findings suggesting its potential in enhancing drug delivery systems. Moreover, the compound's compatibility with biological systems has led to its exploration in bio-based composites, which are increasingly sought after in eco-friendly manufacturing processes.

Recent advancements in analytical techniques have further elucidated the structural and functional properties of Potassium (R)-Glycidate. For instance, high-resolution mass spectrometry has provided deeper insights into its molecular composition, while nuclear magnetic resonance (NMR) spectroscopy has revealed details about its stereochemical arrangement. These findings have not only improved our understanding of the compound but also paved the way for innovative applications.

From a sustainability perspective, Potassium (R)-Glycidate represents a promising avenue for reducing reliance on petroleum-based products. Its derivation from renewable resources aligns with global efforts to transition towards greener chemical processes. As research continues to uncover new functionalities and applications, Potassium (R)-Glycidate is poised to play an increasingly important role in diverse fields.

In conclusion, Potassium (R)-Glycidate (CAS No. 82044-23-3) stands out as a multifaceted compound with significant potential across various industries. Its unique properties, coupled with ongoing research advancements, ensure that it remains at the forefront of chemical innovation.

• 111058-32-3(methyl (2R)-oxirane-2-carboxylate)
• 4538-50-5(methyl oxirane-2-carboxylate)
• 51877-54-4(oxirane-2-carboxylic acid;potassium salt)
• 23943-96-6((2R)-2-methoxypropanoic acid)
• 26023-30-3(Poly[oxy(1-methyl-2-oxo-1,2-ethanediyl)])
• 23953-00-6((2S)-2-methoxypropanoic acid)
• 118712-39-3(methyl (2S)-oxirane-2-carboxylate)
• 6311-64-4(2,3-Oxiranedicarboxylicacid, potassium salt (1:2))
• 503-11-7(oxirane-2-carboxylic acid)
• 55203-13-9(Propanedioic acid, 2,2'-oxybis-)