Cas no 82032-43-7 (Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate)

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate is a versatile heterocyclic compound featuring both a hydroxymethyl and a carboxylate ester functional group on an imidazole core. This structure makes it a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and bioactive molecules. The hydroxymethyl group offers a reactive site for further derivatization, while the ester moiety provides flexibility for hydrolysis or transesterification. Its imidazole ring is conducive to coordination chemistry and metal-binding applications. The compound’s stability under standard conditions and compatibility with common solvents enhance its utility in multistep synthetic routes. Its well-defined reactivity profile ensures reproducibility in research and industrial applications.
Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate structure
82032-43-7 structure
Product Name:Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate
CAS No:82032-43-7
MF:C6H8N2O3
MW:156.139321327209
MDL:MFCD00191520
CID:822848
PubChem ID:87571198
Update Time:2025-05-27

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Chemical and Physical Properties

Names and Identifiers

    • Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate
    • 5-(HYDROXYMETHYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER
    • 5-Hydroxymethyl-1H-Imidazole-4-Carboxylic Acid Methyl Ester
    • Methyl 5-hydroxymethyl-4-imidazolecarboxylate
    • RRNBWPNDHRAYBV-UHFFFAOYSA-N
    • KM2102
    • FCH917878
    • 2698AC
    • OR322726
    • AX8101299
    • ST24033254
    • methyl 5-hydroxymethyl-1H-
    • 1H-Imidazole-4-carboxylic acid, 5-(hydroxymethyl)-, methyl ester (9CI)
    • Methyl 4-(hydroxymethyl)-1H-imidazole-5-carboxylate (ACI)
    • Methyl 5-hydroxymethyl-1H-imidazole-4-carboxylate
    • DB-075807
    • CS-0314532
    • DTXSID00332777
    • N12728
    • 82032-43-7
    • H0840
    • SY052651
    • SCHEMBL2393641
    • MFCD00191520
    • AKOS006229385
    • AS-68766
    • Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate, AldrichCPR
    • methyl 4-(hydroxymethyl)-1h-imidazole-5-carboxylate
    • BP-10750
    • Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate #
    • MDL： MFCD00191520
    • Inchi： 1S/C6H8N2O3/c1-11-6(10)5-4(2-9)7-3-8-5/h3,9H,2H2,1H3,(H,7,8)
    • InChI Key： RRNBWPNDHRAYBV-UHFFFAOYSA-N
    • SMILES： O=C(C1=C(CO)N=CN1)OC

Computed Properties

  • Exact Mass: 156.05300
  • Monoisotopic Mass: 156.05349212g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 151
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 4
  • XLogP3: -0.6
  • Topological Polar Surface Area: 75.2

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.385±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 171-172 oC
  • Boiling Point: 459.1±35.0 °C at 760 mmHg
  • Flash Point: 231.4±25.9 °C
  • Solubility: Dissolution (91 g/l) (25 o C),
  • PSA: 75.21000
  • LogP: -0.31140
  • Solubility: Not determined
  • Vapor Pressure: 0.0±1.2 mmHg at 25°C

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Security Information

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Customs Data

  • HS CODE：2933290090
  • Customs Data：

    China Customs Code:

    2933290090

    Overview:

    2933290090. Other compounds with non fused imidazole ring in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
H0840-5G
Methyl 5-(Hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7 >98.0%(T)
5g
 ￥3450.00 2024-04-15
Chemenu
CM186838-250mg
Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7 95%+
250mg
 $174 2024-07-23
Chemenu
CM186838-1g
Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7 95%+
1g
 $434 2024-07-23
Chemenu
CM186838-5g
Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7 95%+
5g
 $1156 2024-07-23
Apollo Scientific
OR322726-500mg
5-Hydroxymethyl-1H-imidazole-4-carboxylic acid methyl ester
 82032-43-7
500mg
 ￡224.00 2024-05-24
Chemenu
CM186838-5g
Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7 95%
5g
 $834 2021-08-05
TRC
B585338-10mg
Methyl 5-(Hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7
10mg
 $ 50.00 2022-06-07
TRC
B585338-50mg
Methyl 5-(Hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7
50mg
 $ 70.00 2022-06-07
TRC
B585338-100mg
Methyl 5-(Hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7
100mg
 $ 115.00 2022-06-07
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
M863089-250mg
Methyl 5-(Hydroxymethyl)-1H-imidazole-4-carboxylate
 82032-43-7 ≥98%(T)
250mg
 ￥364.50 2022-09-01

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Production Method

Production Method 1

Reaction Conditions
1.1 Catalysts: Acetic acid
Reference
Synthesis of 4,5-disubstituted imidazoles
Kavadias, Gerry; et al, Canadian Journal of Chemistry, 1982, 60(6), 723-9

Production Method 2

Reaction Conditions
1.1 Reagents: Lithium bromide ,  Sodium borohydride
2.1 Catalysts: Acetic acid
Reference
Synthesis of 4,5-disubstituted imidazoles
Kavadias, Gerry; et al, Canadian Journal of Chemistry, 1982, 60(6), 723-9

Production Method 3

Reaction Conditions
1.1 -
2.1 Reagents: Lithium bromide ,  Sodium borohydride
3.1 Catalysts: Acetic acid
Reference
Synthesis of 4,5-disubstituted imidazoles
Kavadias, Gerry; et al, Canadian Journal of Chemistry, 1982, 60(6), 723-9

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Raw materials

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Preparation Products

Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate Related Literature

Related Categories

82032-43-7 (Methyl 5-(hydroxymethyl)-1H-imidazole-4-carboxylate) Related Products

Recommended suppliers
Yunnanjiuzhen
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen
SunaTech Inc.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
SunaTech Inc.
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Shanghai Aoguang Biotechnology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Aoguang Biotechnology Co., Ltd
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.