Cas no 82031-33-2 (2-(2-Methoxyethoxy)benzenesulfonamide)

2-(2-Methoxyethoxy)benzenesulfonamide is a sulfonamide derivative featuring a methoxyethoxy substituent on the benzene ring. This structural modification enhances its solubility in polar organic solvents while maintaining reactivity typical of benzenesulfonamides. The compound is of interest in medicinal chemistry and organic synthesis, where it serves as a versatile intermediate for the development of biologically active molecules. Its ether-linked side chain may improve pharmacokinetic properties, such as membrane permeability, compared to simpler sulfonamide analogs. The product is suitable for use in cross-coupling reactions, nucleophilic substitutions, and as a building block for heterocyclic systems. Proper handling and storage under anhydrous conditions are recommended to ensure stability.
2-(2-Methoxyethoxy)benzenesulfonamide structure
82031-33-2 structure
Product Name:2-(2-Methoxyethoxy)benzenesulfonamide
CAS No:82031-33-2
MF:C9H13NO4S
MW:231.26882147789
MDL:MFCD03265376
CID:60400
Update Time:2025-05-23

2-(2-Methoxyethoxy)benzenesulfonamide Chemical and Physical Properties

Names and Identifiers

    • 2-(2-Methoxyethoxy)benzenesulfonamide
    • 2-(2-METHOXY ETHOXY)-BENZENESULFONAMIDE
    • 2-(1-BENZYL-1H-PYRAZOL-4-YL)-ISONICOTINIC ACID
    • 2-(2-Methoxyethoxy)benzen sulfonamide
    • 2-(2-Methoxyethoxy)benzenesulfonamide (ACI)
    • MDL: MFCD03265376
    • Inchi: 1S/C9H13NO4S/c1-13-6-7-14-8-4-2-3-5-9(8)15(10,11)12/h2-5H,6-7H2,1H3,(H2,10,11,12)
    • InChI Key: UIYMPDRCTPYBLI-UHFFFAOYSA-N
    • SMILES: O=S(C1C(OCCOC)=CC=CC=1)(N)=O

Computed Properties

  • Exact Mass: 231.05700
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 5

Experimental Properties

  • Boiling Point: 411.9°C at 760 mmHg
  • PSA: 87.00000
  • LogP: 2.14030

2-(2-Methoxyethoxy)benzenesulfonamide Security Information

2-(2-Methoxyethoxy)benzenesulfonamide Customs Data

  • HS CODE:2935009090
  • Customs Data:

    China Customs Code:

    2935009090

    Overview:

    2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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2-(2-Methoxyethoxy)benzenesulfonamide Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Sodium nitrite ,  Hydrochloric acid
Reference
Preparation of 2-alkoxybenzenesulfonamides
, European Patent Organization, , ,

2-(2-Methoxyethoxy)benzenesulfonamide Raw materials

2-(2-Methoxyethoxy)benzenesulfonamide Preparation Products

2-(2-Methoxyethoxy)benzenesulfonamide Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:82031-33-2)2-(2-Methoxyethoxy)benzenesulfonamide
Order Number:A840237
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 06:49
Price ($):222.0

Additional information on 2-(2-Methoxyethoxy)benzenesulfonamide

2-(2-Methoxyethoxy)benzenesulfonamide (CAS No. 82031-33-2): A Comprehensive Overview

2-(2-Methoxyethoxy)benzenesulfonamide (CAS No. 82031-33-2) is a specialized organic compound that has garnered significant attention in the chemical and pharmaceutical industries. This sulfonamide derivative is characterized by its unique molecular structure, which includes a methoxyethoxy substituent attached to a benzene ring. The compound's versatility and potential applications make it a subject of interest for researchers and industry professionals alike.

The chemical properties of 2-(2-Methoxyethoxy)benzenesulfonamide are largely influenced by its functional groups. The sulfonamide moiety provides the compound with distinctive reactivity, making it useful in various synthetic pathways. Additionally, the methoxyethoxy group enhances its solubility in organic solvents, which is a critical factor in many industrial applications. Researchers often explore its behavior under different conditions to optimize its use in complex chemical processes.

One of the most common queries related to 2-(2-Methoxyethoxy)benzenesulfonamide is its role in pharmaceutical development. The compound has been investigated for its potential as an intermediate in the synthesis of bioactive molecules. Its structural features make it a candidate for drug design, particularly in the development of sulfonamide-based therapeutics. This aligns with the growing interest in targeted drug delivery systems and small-molecule inhibitors, which are hot topics in modern pharmacology.

In addition to its pharmaceutical applications, 2-(2-Methoxyethoxy)benzenesulfonamide is also explored in material science. Its ability to act as a building block for polymers and coatings has been studied, particularly in contexts where chemical resistance and thermal stability are required. This ties into the broader trend of developing high-performance materials for industrial use, a topic frequently searched by engineers and researchers.

The synthesis of 2-(2-Methoxyethoxy)benzenesulfonamide typically involves multi-step organic reactions, starting from readily available precursors. Optimizing these synthetic routes is a key area of research, as it impacts the compound's scalability and cost-effectiveness. Questions about efficient synthesis methods and yield improvement are common among chemists, reflecting the demand for sustainable and economical production processes.

Environmental and safety considerations are also critical when working with 2-(2-Methoxyethoxy)benzenesulfonamide. While the compound is not classified as hazardous under standard regulations, proper handling and disposal practices are essential to minimize any potential risks. This aligns with the increasing focus on green chemistry and sustainable practices in the chemical industry, topics that resonate with environmentally conscious professionals.

Market trends indicate a steady demand for 2-(2-Methoxyethoxy)benzenesulfonamide, driven by its applications in pharmaceuticals and advanced materials. Suppliers and manufacturers are keen to understand the global supply chain dynamics and pricing trends for this compound, which are frequently searched terms in business and trade databases. The compound's niche yet growing market makes it a subject of interest for stakeholders across the value chain.

In summary, 2-(2-Methoxyethoxy)benzenesulfonamide (CAS No. 82031-33-2) is a multifaceted compound with significant potential in both scientific and industrial domains. Its unique properties, coupled with its applicability in cutting-edge research, ensure its continued relevance in the chemical landscape. Whether you're a researcher, manufacturer, or end-user, understanding this compound's capabilities and market dynamics can provide valuable insights for your work.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:82031-33-2)2-(2-Methoxyethoxy)benzenesulfonamide
A840237
Purity:99%
Quantity:100g
Price ($):222.0
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