Cas no 81-30-1 (1,4,5,8-Naphthalenetetracarboxylic dianhydride)

1,4,5,8-Naphthalenetetracarboxylic dianhydride (NTCDA) is a high-purity organic compound primarily used as a key intermediate in the synthesis of advanced materials, including polyimides, dyes, and pigments. Its rigid, planar structure and reactive anhydride groups make it valuable for producing thermally stable polymers with excellent mechanical and dielectric properties. NTCDA is also employed in the fabrication of n-type organic semiconductors due to its electron-accepting capabilities, contributing to applications in organic electronics and optoelectronic devices. The compound’s high thermal stability and chemical resistance further enhance its suitability for demanding industrial and research applications. Proper handling is required due to its reactivity with moisture and amines.
1,4,5,8-Naphthalenetetracarboxylic dianhydride structure
81-30-1 structure
Product Name:1,4,5,8-Naphthalenetetracarboxylic dianhydride
CAS No:81-30-1
MF:C14H4O6
MW:268.17796421051
MDL:MFCD00006915
CID:34246
PubChem ID:6678
Update Time:2025-06-07

1,4,5,8-Naphthalenetetracarboxylic dianhydride Chemical and Physical Properties

Names and Identifiers

    • naphthalene-1,4,5,8-tetracarboxylic acid
    • Naphthalene-1,4,5,8-tetracarboxylic acid dianhydride
    • 1,4,5,8-Naphthalenetetracarboxylic dianhydride
    • Naphthalene-1,4,5,8-tetracarboxylic Dianhydride (purified by sublimation)
    • 1.4.5.8-Naphthalenetetracarboxylicdianhydride
    • Naphthalene-1,4,5,8-tetracarboxylic Dianhydride
    • NTCDA
    • Nickel broMide
    • NTCDA (purified by sublimation)
    • NTDA
    • Isochromeno[6,5,4-def]isochromene-1,3,6,8-tetraone
    • Naphthalenetetracarboxylic dianhydride
    • Naphthalene-1,8:4,5-tetracarboxylic dianhydride
    • 2,7-Dioxapyrene-1,3,6,8-tetrone
    • 1,8:4,5-Naphthalenetetracarboxylic dianhydride
    • 1,4,5,8-Naphthalenetetracarboxylic acid anhydride
    • 1,4,5,8-Naphthalenetetracarboxylic acid dianhydride
    • L56XQD1V6Y
    • [2]Benzopyrano[6,5,4-def][2]benzopyran-1,3,6,8-te
    • C14-H4-O6
    • 1,4,5,8-NAPHTHALENETETRACARBOXYLIC ACID, 1,8:4,5-DIANHYDRIDE
    • MFCD00006915
    • 1,4,5, 8-Naphthalenetetracarboxylic acid dianhydride
    • 1,4,5,8-Naphthalenetetracarboxylic dianhydride treated HSA
    • Isochromeno[6,5,4-def]isochromene-1,3,6,8-tetrone #
    • 1,8:4, 5-Naphthalenetetracarboxylic dianhydride
    • 2,7-Dioxapyrene-1,3,6, 8-tetrone
    • EINECS 201-342-5
    • 5-19-05-00423 (Beilstein Handbook Reference)
    • NSC 84241
    • BRN 0272788
    • NSC-84241
    • 1,4,5,8-Naphthalenetetracarboxylic dianhydride (NTDA)
    • 1,4,5,8-naphthalene tetracarboxylic acid dianhydride
    • Tox21_304005
    • NAPHTHALIC 1,8:4,5-DIANHYDRIDE
    • [2]Benzopyrano[6,5,4-def][2]benzopyran-1,3,6,8-tetrone
    • 1,5,8-Naphthalenetetracarboxylic dianhydride
    • EN300-220051
    • Q-200077
    • N0369
    • A840089
    • [2]Benzopyrano[6,4-def][2]benzopyran-1,3,6,8-tetrone
    • 1,4,5, 8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride
    • 1,4,5,8-Naphthalenetetracarboxylic dianhydride treated gelatin
    • {[2]Benzopyrano[6,5,4-def][2]benzopyran-1,3,6,8-tetrone}
    • (2)Benzopyrano(6,5,4-def)(2)benzopyran-1,3,6,8-tetrone
    • 1,5,8-Naphthalenetetracarboxylic acid anhydride
    • 6,13-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1,3,8,10,15-pentaene-5,7,12,14-tetrone
    • 1,4,5,8-naphthalenetetracar-boxylic dianhydride
    • DTXSID4052554
    • NSC84241
    • 1,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride
    • AKOS003614689
    • 1,4,5,8-Naphthalenetetracarboxylicdianhydride;Isochromeno[6,5,4-def]isochromene-1,3,6,8-tetraone
    • 1,4,5,8-naphthalenetetracarboxylicdianhydride
    • 1,4,5,8-Naphthalenetetracarboxylic dianhydride treated BSA
    • UNII-L56XQD1V6Y
    • LS-94955
    • C14H4O6
    • 1,5,8-Naphthalenetetracarboxylic acid dianhydride
    • DTXCID1031127
    • 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5 dianhydride
    • 1,4,5,8-Naphthalene, tetracarboxylic 1,8:4,5-dianhydride
    • 1,5-Naphthalenetetracarboxylic dianhydride
    • NCGC00357221-01
    • SCHEMBL148025
    • Isochromeno[6,5,4-def]isochromene-1,3,6,8-tetrone
    • 1,4,5,8-naphthalene tetracarboxylic dianhydride
    • 1,4,5,8-naphthalenetetracarboxylic-1,8:4,5-dianhydride
    • 2,3,6,8-tetrone
    • 81-30-1
    • N0755
    • 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride
    • 1,4,5, 8-Naphthalenetetracarboxylic acid anhydride
    • s10066
    • CAS-81-30-1
    • Naphthalene-1,4,5,8-tetracarboxylic Dianhydride, (purified by sublimation)
    • FT-0606752
    • 6,13-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),2,4(16),8,10-pentaene-5,7,12,14-tetrone
    • 1,4,5, 8-Naphthalenetetracarboxylic dianhydride
    • NS00038115
    • 1,4,5,8-Naphthalenetetracarboxylic 1,8:4,5-dianhydride (7CI, 8CI)
    • Naphthalenetetracarboxylic dianhydride (6CI)
    • 1,4,5,8-Naphthalenetetracarboxylic acid-1,8:4,5-dianhydride
    • 1,4,5,8-Naphthalic dianhydride
    • 1,4,5,8-Tetracarboxynaphthalene dianhydride
    • Naphthalene-4,5,8,9-tetracarboxylic dianhydride
    • Naphthalenetetracarboxylic anhydride
    • DB-056510
    • 1,4,5,8-Naphthalenetetracarboxylic dianhydride; NTCDA
    • MDL： MFCD00006915
    • Inchi： 1S/C14H4O6/c15-11-5-1-2-6-10-8(14(18)20-12(6)16)4-3-7(9(5)10)13(17)19-11/h1-4H
    • InChI Key： YTVNOVQHSGMMOV-UHFFFAOYSA-N
    • SMILES： O=C1C2C3C(=CC=C4C=3C(=CC=2)C(=O)OC4=O)C(=O)O1
    • BRN： 0272788

Computed Properties

  • Exact Mass: 268.00100
  • Monoisotopic Mass: 268.001
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 0
  • Complexity: 446
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 1.9
  • Topological Polar Surface Area: 86.7

Experimental Properties

  • Color/Form: Yellowish powder
  • Density: 1.5122 (rough estimate)
  • Melting Point: >300?°C (lit.)
  • Boiling Point: 617°C at 760 mmHg
  • Flash Point: 280.4oC
  • Refractive Index: 1.5230 (estimate)
  • PSA: 86.74000
  • LogP: 1.46100
  • Sensitiveness: Moisture Sensitive
  • Solubility: Uncertain.
  • Vapor Pressure: 0.0±1.8 mmHg at 25°C

1,4,5,8-Naphthalenetetracarboxylic dianhydride Security Information

  • Symbol: GHS07
  • Prompt：warning
  • Signal Word：Warning
  • Hazard Statement： H315,H319,H335
  • Warning Statement： P261,P305+P351+P338
  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：2
  • Hazard Category Code： 36/37/38
  • Safety Instruction： S26-S36
  • FLUKA BRAND F CODES：10-21
  • RTECS：QK3695000
  • Hazardous Material Identification： Xi
  • TSCA：Yes
  • Risk Phrases：R36/37/38
  • Storage Condition：Argon filled storage

1,4,5,8-Naphthalenetetracarboxylic dianhydride Customs Data

  • HS CODE：29173990

1,4,5,8-Naphthalenetetracarboxylic dianhydride Pricemore >>

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1,4,5,8-Naphthalenetetracarboxylic dianhydride Production Method

Production Method 1

Reaction Conditions
1.1 Solvents: Acetic acid ;  16 h, reflux
Reference
Dinaphtho[1,8-bc:1',8'-fg][1,5]dithiocine Bisimide
Tanaka, Yuki; et al, Asian Journal of Organic Chemistry, 2021, 10(3), 541-544

Production Method 2

Reaction Conditions
1.1 Reagents: Sodium dichromate Catalysts: Sulfuric acid Solvents: Water
2.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 3

Reaction Conditions
1.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 4

Reaction Conditions
1.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 5

Reaction Conditions
1.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 6

Reaction Conditions
1.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 7

Reaction Conditions
1.1 Reagents: Oxygen Solvents: Dichloromethane ;  12 - 60 min
2.1 Reagents: Oxygen Solvents: Dichloromethane
Reference
NTCDA-TTF first axial fusion: emergent panchromatic, NIR optical, multi-state redox and high optical contrast photooxidation
Asthana, Deepak; et al, Chemical Communications (Cambridge, 2012, 48(52), 6475-6477

Production Method 8

Reaction Conditions
1.1 Reagents: Potassium hydroxide Solvents: Water
2.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 9

Reaction Conditions
1.1 Reagents: Sulfur tetrafluoride
Reference
Fluorination by Sulfur Tetrafluoride
Wang, Chia-Lin J., Organic Reactions (Hoboken, 1985, 34,

Production Method 10

Reaction Conditions
1.1 Reagents: Acetic acid ,  Cobalt diacetate ;  110 °C; 10 min, 40 °C
1.2 Reagents: Acetic acid ,  Peracetic acid ;  50 °C
1.3 Reagents: Potassium hydroxide ,  Sodium hypochlorite ;  pH 10, 50 °C
1.4 Reagents: Sodium bicarbonate ;  pH 1, 80 °C
1.5 Reagents: Hydrochloric acid ;  cooled
Reference
New xanthene structures
Iscrulescu, Lucian; et al, Revista de Chimie (Bucharest, 2008, 59(5), 578-581

Production Method 11

Reaction Conditions
1.1 Reagents: Sodium iodide ,  Cadmium chloride ;  > 3 h, 3 MPa, 430 - 450 °C; cooled
1.2 Reagents: Water
1.3 Reagents: Hydrochloric acid Solvents: Water ;  rt; 1 h, pH 1 - 2, rt
1.4 Solvents: Methanol ;  rt; > 6 h, 150 °C
Reference
Synthesis and structural characterization of organic semiconductor NTCDA
Li, Jian-feng; et al, Gongneng Cailiao Yu Qijian Xuebao, 2007, 13(6), 630-634

Production Method 12

Reaction Conditions
1.1 Reagents: Oxygen Solvents: Dichloromethane
Reference
NTCDA-TTF first axial fusion: emergent panchromatic, NIR optical, multi-state redox and high optical contrast photooxidation
Asthana, Deepak; et al, Chemical Communications (Cambridge, 2012, 48(52), 6475-6477

Production Method 13

Reaction Conditions
1.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 14

Reaction Conditions
1.1 Solvents: Acetic anhydride ;  18 h, 140 °C
Reference
Electronic and assembly properties of a water-soluble blue naphthalene diimide
Welsh, Thomas A.; et al, New Journal of Chemistry, 2021, 45(31), 14005-14013

Production Method 15

Reaction Conditions
1.1 Solvents: Toluene ,  Dimethylacetamide ;  2 h, 111 °C; 111 °C → 10 °C; overnight, 10 °C
Reference
Conformationally rigid molecular and polymeric naphthalene-diimides containing C6H6N2 constitutional isomers
Abbinante, Vincenzo Mirco; et al, Journal of Materials Chemistry C: Materials for Optical and Electronic Devices, 2021, 9(33), 10875-10888

Production Method 16

Reaction Conditions
Reference
Stack Exchange Strategies for the Synthesis of Covalent Double-Channel Photosystems by Self-Organizing Surface-Initiated Polymerization
Sakai, Naomi; et al, Journal of the American Chemical Society, 2011, 133(46), 18542-18545

Production Method 17

Reaction Conditions
1.1 Reagents: Sulfuric acid Solvents: Water
2.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

Production Method 18

Reaction Conditions
1.1 Reagents: Sulfuric acid
2.1 Reagents: Potassium hypochlorite Solvents: Water
Reference
Derivatives of 1,4,5,8-naphthalenetetracarboxylic acid. IV. Oxidation of 1,6- and 1,8-pyrenequinones with alkali metal hypochlorites
Shigalevskii, V. A.; et al, Zhurnal Organicheskoi Khimii, 1985, 21(7), 1506-13

1,4,5,8-Naphthalenetetracarboxylic dianhydride Raw materials

1,4,5,8-Naphthalenetetracarboxylic dianhydride Preparation Products

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Suzhou Senfeida Chemical Co., Ltd
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(CAS:81-30-1)1,4,5,8-naphthalenetetracarboxylic dianhydride
Order Number:sfd610
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:81-30-1)Naphthalene-1,4,5,8-tetracarboxylic Dianhydride, ≥ 95.0%
Order Number:LE16681;LE1695802
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
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Amadis Chemical Company Limited
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(CAS:81-30-1)1,4,5,8-Naphthalenetetracarboxylic dianhydride
Order Number:A840089
Stock Status:in Stock
Quantity:500g/1kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 06:48
Price ($):238.0/469.0

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Suzhou Senfeida Chemical Co., Ltd
(CAS:81-30-1)1,4,5,8-naphthalenetetracarboxylic dianhydride
sfd610
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:81-30-1)Naphthalene-1,4,5,8-tetracarboxylic Dianhydride, ≥ 95.0%
LE16681;LE1695802
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
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