Production Method 1

1747-60-0

808755-67-1

Reaction Conditions

1.1 Reagents: Isoamyl nitrite ,  Copper bromide (CuBr2) Solvents: Acetonitrile ;  65 °C
2.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  2 h, rt

Reference

Synthesis of Firefly Luciferin Analogues and Evaluation of the Luminescent Properties

Ioka, Shuji; et al, Chemistry - A European Journal, 2016, 22(27), 9330-9337

Production Method 2

2941-58-4

808755-67-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  2 h, rt

Reference

Synthesis of Firefly Luciferin Analogues and Evaluation of the Luminescent Properties

Ioka, Shuji; et al, Chemistry - A European Journal, 2016, 22(27), 9330-9337

Production Method 3

2941-58-4

808755-67-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  0 °C; 10 min, 0 °C; 27 h, rt
1.2 Reagents: Methanol ;  0 °C

Reference

Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

Bort, Guillaume; et al, European Journal of Medicinal Chemistry, 2014, 87, 843-861

Production Method 4

1747-60-0

808755-67-1

Reaction Conditions

1.1 Reagents: p-Toluenesulfonic acid ,  Isoamyl nitrite ,  Tetrabutylammonium bromide Catalysts: Copper bromide (CuBr2) Solvents: Acetonitrile ;  45 min, 25 °C
2.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  -78 °C; -78 °C → rt; 16 h, rt
2.2 Reagents: Ammonium chloride Solvents: Water ;  rt

Reference

Multicomponent Bioluminescence Imaging with a π-Extended Luciferin

Yao, Zi; et al, Journal of the American Chemical Society, 2020, 142(33), 14080-14089

Production Method 5

1747-60-0

808755-67-1

Reaction Conditions

1.1 Reagents: tert-Butyl nitrite ,  Copper bromide (CuBr2) Solvents: Acetonitrile ;  2.5 d, rt; 1.5 h, rt → 65 °C
1.2 Reagents: Hydrochloric acid Solvents: Water
2.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  0 °C; 10 min, 0 °C; 27 h, rt
2.2 Reagents: Methanol ;  0 °C

Reference

Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

Bort, Guillaume; et al, European Journal of Medicinal Chemistry, 2014, 87, 843-861

2-Bromobenzodthiazol-6-ol Raw materials

• 2-Bromo-6-methoxy-1,3-benzothiazole
• 6-methoxy-1,3-benzothiazol-2-amine

2-Bromobenzodthiazol-6-ol Preparation Products

• 2-Bromobenzodthiazol-6-ol (808755-67-1)

• 1. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 2. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
• 3. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 4. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 5. Dissociative electron attachment to HGaF4 Lewis–Br?nsted superacid
  Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzothiazoles Benzothiazoles
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzothiazoles

• 2941-58-4(2-Bromo-6-methoxy-1,3-benzothiazole)
• 408328-13-2(2,6-Dibromobenzothiazole)
• 864169-36-8(2-bromo-5,6-dimethoxy-1,3-benzothiazole)
• 412923-38-7(Benzothiazole,2-bromo-6-ethoxy-)
• 3622-39-7(2-Bromo-4-methoxybenzodthiazole)
• 2516-40-7(2-Bromo-1,3-benzothiazole)
• 214337-39-0(2-bromo-5-methoxy-1,3-benzothiazole)
• 1019111-64-8(2,5-Dibromo-benzothiazole)
• 628725-99-5(2-Bromo-6-(trifluoromethoxy)benzothiazole)
• 3622-45-5(2-bromo-7-methoxy-1,3-benzothiazole)