Cas no 80745-10-4 (H-Arg(Mtr)-OH H2O)

H-Arg(Mtr)-OH·H?O is a protected derivative of L-arginine, where the guanidine group is shielded by the 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) protecting group. This compound is widely used in peptide synthesis to prevent unwanted side reactions during coupling steps, ensuring high purity and yield. The Mtr group offers selective deprotection under mild acidic conditions, making it suitable for sensitive peptide sequences. The inclusion of water (H?O) in the formulation enhances stability and handling. Its compatibility with standard solid-phase and solution-phase synthesis protocols makes it a versatile choice for researchers. This reagent is particularly valuable in constructing complex peptides requiring orthogonal protection strategies.
H-Arg(Mtr)-OH H2O structure
H-Arg(Mtr)-OH H2O structure
Product Name:H-Arg(Mtr)-OH H2O
CAS No:80745-10-4
MF:C16H26N4O5S
MW:386.466442584991
MDL:MFCD00057846
CID:60256
PubChem ID:24886795
Update Time:2025-06-07

H-Arg(Mtr)-OH H2O Chemical and Physical Properties

Names and Identifiers

    • N'-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
    • H-Arg(Mtr)-OH
    • Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
    • (S)-2-Amino-5-(3-((4-methoxy-2,3,6-trimethylphenyl)sulfonyl)guanidino)pentanoic acid
    • H-ARG(MTR)-OH·H2O
    • H-Arg(Mtr)-OH·H2O N-ω-4-methoxy-2,3,6-trimethylbenzenesulfonyl-L-arginine monohydrate
    • H-L-Arg(Mtr)-OH
    • L-ARGINYL-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL
    • 2H2O
    • AMINO ACID SERIES
    • ARGININE(MTR)-OH
    • H-Arg(Mtr)-OH.1
    • H-Arg(Mtr)-OH?1
    • N-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
    • CS-W011745
    • O-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
    • N
    • Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine, >=98.0% (TLC)
    • Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
    • Nw-((4-Methoxy-2,3,6-trimethylphenyl)sulfonyl)-L-arginine
    • 80745-10-4
    • DS-16176
    • SCHEMBL18468371
    • (S)-2-amino-5-(3-(4-methoxy-2,3,6-trimethylphenylsulfonyl)guanidino)pentanoic acid
    • AKOS016842846
    • (2S)-2-amino-5-[[amino-[(4-methoxy-2,3,6-trimethylphenyl)sulfonylamino]methylidene]amino]pentanoic acid
    • Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine
    • HY-W011029
    • N5-[Imino[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]methyl]-L-ornithine (ACI)
    • H-Arg(Mtr)-OH H2O
    • MDL: MFCD00057846
    • Inchi: 1S/C16H26N4O5S/c1-9-8-13(25-4)10(2)11(3)14(9)26(23,24)20-16(18)19-7-5-6-12(17)15(21)22/h8,12H,5-7,17H2,1-4H3,(H,21,22)(H3,18,19,20)/t12-/m0/s1
    • InChI Key: FUSAEZSSVDNYPO-LBPRGKRZSA-N
    • SMILES: S(C1C(C)=CC(OC)=C(C)C=1C)(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)O

Computed Properties

  • Exact Mass: 386.16200
  • Monoisotopic Mass: 386.162
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 5
  • Hydrogen Bond Acceptor Count: 9
  • Heavy Atom Count: 26
  • Rotatable Bond Count: 10
  • Complexity: 604
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 166A^2
  • XLogP3: -1.6

Experimental Properties

  • Density: 1.3600
  • Boiling Point: 615.4°C at 760 mmHg
  • Flash Point: 326°C
  • Refractive Index: 1.593
  • PSA: 162.98000
  • LogP: 3.27780
  • Sensitiveness: Moisture Sensitive

H-Arg(Mtr)-OH H2O Security Information

  • WGK Germany:3
  • Storage Condition:Store in cold storage.

H-Arg(Mtr)-OH H2O Pricemore >>

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H-Arg(Mtr)-OH H2O Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Acetic acid ,  Methanol ,  Water
Reference
Solution synthesis of the heptadecapeptide sequence of vespulakinin 1
Biondi, Laura; et al, Gazzetta Chimica Italiana, 1988, 118(6), 427-33

H-Arg(Mtr)-OH H2O Raw materials

H-Arg(Mtr)-OH H2O Preparation Products

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