Cas no 80485-89-8 (N-1H-Indol-3-ylformamide)

N-1H-Indol-3-ylformamide structure
N-1H-Indol-3-ylformamide structure
Product Name:N-1H-Indol-3-ylformamide
CAS No:80485-89-8
MF:C9H8N2O
MW:160.17262172699
CID:6624962
Update Time:2024-01-15

N-1H-Indol-3-ylformamide Chemical and Physical Properties

Names and Identifiers

    • N-(1H-indol-3-yl)formamide
    • N-1H-Indol-3-ylformamide
    • Inchi: 1S/C9H8N2O/c12-6-11-9-5-10-8-4-2-1-3-7(8)9/h1-6,10H,(H,11,12)
    • InChI Key: ZZCLANUFFNXARO-UHFFFAOYSA-N
    • SMILES: C(NC1C2=C(NC=1)C=CC=C2)=O

Experimental Properties

  • Density: 1.349±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
  • Boiling Point: 438.9±18.0 °C(Predicted)
  • pka: 15.82±0.30(Predicted)

N-1H-Indol-3-ylformamide Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Formic acid ,  Hydrogen Catalysts: Palladium Solvents: Methanol ;  3 h, -10 °C; 1 h, -10 °C → 10 °C
Reference
The first isocyanide of plant origin expands functional group diversity in cruciferous phytoalexins: synthesis, structure and bioactivity of isocyalexin A
Pedras, M. Soledade C.; et al, Organic & Biomolecular Chemistry, 2012, 10(18), 3613-3616

N-1H-Indol-3-ylformamide Raw materials

N-1H-Indol-3-ylformamide Preparation Products

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