• 1. Fe3O4 nanosphere@microporous organic networks: enhanced anode performances in lithium ion batteries through carbonization?
  Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
• 2. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
• 3. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 4. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 5. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026

• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes

Professional Introduction of 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde (CAS No. 80395-32-0)

The compound 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde ( CAS No. 80395-32-0 ) is a unique organic molecule that has garnered significant attention in the field of pharmaceutical chemistry and drug discovery. This compound belongs to the class of naphthalene derivatives, which are known for their diverse applications in medicine and biotechnology. The structure of this compound features a naphthalene ring system with a difluoromethoxy group at position 2 and a carbaldehyde group at position 1, making it a highly functionalized aromatic compound.

Recent studies have highlighted the potential of difluoromethoxy groups in enhancing the pharmacokinetic properties of drugs. The presence of this group in 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde may contribute to improved bioavailability and targeted delivery, which are critical factors in drug development. Additionally, the naphthalene core provides a rigid framework that can facilitate molecular interactions with biological targets, such as enzymes and receptors.

The synthesis of 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde involves multi-step organic reactions, including fluorination and aldehyde formation. The compound's synthesis has been optimized to ensure high purity and yield, which are essential for its use in preclinical studies and clinical trials. Advanced analytical techniques, such as HPLC and NMR, have been employed to characterize this compound, confirming its structural integrity and stability.

In terms of applications, 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde has shown promising potential in the development of anticancer agents. Its naphthalene moiety is known to exhibit cytotoxicity against various cancer cell lines, while the difluoromethoxy group may modulate its pharmacokinetic profile to enhance therapeutic efficacy. Furthermore, this compound has been explored as a candidate for modulating enzymatic activity, making it a valuable tool in enzyme inhibition studies.

Recent research has also investigated the neuroprotective properties of 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde. Studies suggest that this compound may possess anti-inflammatory and antioxidant activities, which are crucial for neurodegenerative diseases such as Alzheimer's and Parkinson's. These findings underscore the broad therapeutic potential of this compound across multiple disease areas.

The use of naphthalene derivatives in biomedical research is not new, but the incorporation of fluorinated groups has opened up new avenues for drug design. The difluoromethoxy group in this compound adds a layer of complexity to its pharmacological profile, making it a subject of interest for medicinal chemists and pharmacologists alike. Its unique combination of structural features makes it a versatile tool for exploring various biological pathways.

Overall, 2-Difluoromethoxy-Naphthalene-1-Carbaldehyde ( CAS No. 80395-32-0 ) represents an exciting frontier in the field of pharmaceutical chemistry. Its unique structure, coupled with its potential applications in oncology, neuroscience, and enzyme inhibition, positions it as a valuable asset in the quest for novel therapeutic agents. Continued research into this compound is expected to yield significant advances in our understanding of its pharmacological properties and its potential as a drug candidate.

• 94651-33-9(2-(Trifluoromethoxy)benzaldehyde)
• 147249-30-7(2-(difluoromethoxy)-5-methylbenzaldehyde)
• 71663-53-1(2-(Difluoromethoxy)benzaldehyde)
• 66988-93-0((difluoromethoxy)benzaldehyde)
• 71653-64-0(2-(Difluoromethoxy)benzaldehyde)
• 145742-58-1(Benzaldehyde, 2,5-bis(difluoromethoxy)-)
• 886503-52-2(4-methoxy-2-(trifluoromethoxy)benzaldehyde)
• 145742-65-0(2-Methoxy-5-(trifluoromethoxy)benzaldehyde)
• 221013-25-8(Benzaldehyde,2-(fluoromethoxy)-)
• 749920-58-9(4-(difluoromethoxy)-3,5-dimethylbenzaldehyde)