Cas no 80321-63-7 (Gypenoside IX)

Gypenoside IX is a bioactive saponin compound primarily derived from Gynostemma pentaphyllum (Jiaogulan). It exhibits notable pharmacological properties, including antioxidant, anti-inflammatory, and potential neuroprotective effects. Structurally, it belongs to the dammarane-type triterpenoid saponins, characterized by its specific sugar moieties and aglycone core. Research suggests Gypenoside IX may modulate cellular signaling pathways, such as AMPK and NF-κB, contributing to its therapeutic potential in metabolic and inflammatory disorders. Its high purity and standardized isolation make it suitable for pharmacological studies and nutraceutical applications. Analytical methods like HPLC and LC-MS ensure consistent quality, supporting its use in research on natural product-derived therapeutics.

Gypenoside IX structure

Product Name:Gypenoside IX

CAS No:80321-63-7

MF:C₄₇H₈₀O₁₇

MW:917.127917289734

CID:721475

PubChem ID:46887681

Update Time:2025-05-28

Gypenoside IX Chemical and Physical Properties

Names and Identifiers

- b-D-Glucopyranoside, (3b,12b)-3-(b-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-b-D-xylopyranosyl-
- 3-O-β-D-Glucopyranosyl-20-O-<α-L-arabinopyranosyl(1->6)-β-D-glucopyranosyl>-20(S)-protopanaxadiol
- Notoginsenoside Fd
- Stevenleaf
- Ginsenoside C-Mx1
- Gynosaponin I
- Gynostemma Extract
- Gypenoside
- GYPENOSIDE IX
- SS-D-GLUCOPYRANOSIDE, (3SS,12SS)-3-(SS-D-GLUCOPYRANOSYLOXY)-12-HYDROXYDAMMAR-24-EN-20-YL 6-O-SS-D-XYLOPYRANOSYL-
- (3beta,12beta)-3-(beta-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside
- 2-(Hydroxymethyl)-6-[[(5S,8R,9R,10R,13R,14R)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-
- CG0047
- SW219585-1
- (2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9S,10R,12R,13R,14R,17R)-12-hydroxy-4,4,8,10,14-pent
- (3β,12β)-3-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside (ACI)
- Dammarane, β-D-glucopyranoside deriv. (ZCI)
- 3-O-Glucosylginsenoside C-Mx
- MS-31714
- Ginsenoside C-Mx1; Gynosaponin I; Gypenoside IX
- (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
- AC-34770
- AKOS022168210
- s2306
- BDBM50317535
- CCG-270573
- CHEMBL1095009
- Gynostemma pentaphyllum
- CS-5342
- NCGC00386168-01
- 80321-63-7
- DTXSID001317599
- HY-N0167
- B0005-479871
- FT-0777164
- 2-(hydroxymethyl)-6-[[12-hydroxy-4,4,8,10,14-pentamethyl-17-[6-methyl-2-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
- (2R,3R,4S,5S,6R)-2-{[(1S,3aR,3bR,5aR,7S,9aR,9bR,11R,11aR)-11-hydroxy-3a,3b,6,6,9a-pentamethyl-1-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hept-5-en-2-yl]-dodecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
- BRD-K58775955-001-02-4
- DA-67789
- Gypenoside IX
- MDL： MFCD10566702
- Inchi： 1S/C47H80O17/c1-22(2)10-9-14-47(8,64-42-39(58)36(55)34(53)27(62-42)21-60-40-37(56)32(51)25(50)20-59-40)23-11-16-46(7)31(23)24(49)18-29-44(5)15-13-30(43(3,4)28(44)12-17-45(29,46)6)63-41-38(57)35(54)33(52)26(19-48)61-41/h10,23-42,48-58H,9,11-21H2,1-8H3/t23-,24+,25+,26+,27+,28-,29+,30-,31-,32-,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,44-,45+,46+,47-/m0/s1
- InChI Key： ZTQSADJAYQOCDD-HUGMCNGHSA-N
- SMILES： C[C@@]12CC[C@H]3C([C@H](CC[C@]3(C)[C@H]1C[C@@H](O)[C@@H]1[C@H](CC[C@@]21C)[C@](C)(CC/C=C(\C)/C)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)O1)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)(C)C

Computed Properties

Exact Mass: 916.54000
Monoisotopic Mass: 916.53955108 g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 11
Hydrogen Bond Acceptor Count: 17
Heavy Atom Count: 64
Rotatable Bond Count: 12
Complexity: 1630
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 18
Undefined Atom Stereocenter Count : 6
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: 1.9
Topological Polar Surface Area: 278
Molecular Weight: 917.1

Experimental Properties

Color/Form: White powder
Density: 1.36
Melting Point: No data available
Boiling Point: 982.5±65.0 °C at 760 mmHg
Flash Point: 548.0±34.3 °C
Refractive Index: 1.597
Solubility: 生物體外In Vitro:DMSO溶解度25 mg/mL(27.26 mM;Need ultrasonic)H2O< 0.1 mg/mL(insoluble)
PSA: 277.91000
LogP: 0.61230

Gypenoside IX Security Information

Signal Word：warning
Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care
Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Gypenoside IX Pricemore >>

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