Production Method 1

79636-93-4

79636-94-5

Reaction Conditions

1.1 Reagents: Copper sulfate

Reference

Facile conversion of electron rich benzylic hydrocarbons to carbonyl compounds by peroxydisulfate and copper ions

Bhatt, M. Vivekananda; Perumal, P. Thirumalai, Tetrahedron Letters, 1981, 22(27), 2605-8

Production Method 2

1761-61-1

79636-94-5

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ;  overnight, rt

Reference

Structural Simplification of a Tetrahydroquinoline-Core Peptidomimetic μ-Opioid Receptor (MOR) Agonist/δ-Opioid Receptor (DOR) Antagonist Produces Improved Metabolic Stability

Henry, Sean P.; Fernandez, Thomas J.; Anand, Jessica P.; Griggs, Nicholas W.; Traynor, John R.; et al, Journal of Medicinal Chemistry, 2019, 62(8), 4142-4157

Production Method 3

1761-61-1

79636-94-5

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ;  2 d, rt

Reference

Synthesis and bioevaluation of substituted chalcones, coumaranones and other flavonoids as anti-HIV agents

Cole, Amy L.; Hossain, Sandra; Cole, Alex M.; Phanstiel, Otto IV, Bioorganic & Medicinal Chemistry, 2016, 24(12), 2768-2776

Production Method 4

1761-61-1

79636-94-5

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ;  2 d, rt

Reference

Development of Flavonoid-Based Inverse Agonists of the Key Signaling Receptor US28 of Human Cytomegalovirus

Kralj, Ana; Nguyen, Mai-Thao; Tschammer, Nuska; Ocampo, Nicolette; Gesiotto, Quinto; et al, Journal of Medicinal Chemistry, 2013, 56(12), 5019-5032

5-Bromo-2-ethoxybenzaldehyde Raw materials

• 5-Bromo-2-hydroxybenzaldehyde
• 4-Bromo-1-ethoxy-2-methylbenzene

5-Bromo-2-ethoxybenzaldehyde Preparation Products

• 5-Bromo-2-ethoxybenzaldehyde (79636-94-5)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Phenol ethers
• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)