Cas no 78955-90-5 (Methyl 4-chloro-2-methoxybenzoate)

Methyl 4-chloro-2-methoxybenzoate is a versatile benzoate ester used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its key advantages include high purity, stability under standard conditions, and reactivity in esterification and substitution reactions. The compound is particularly valued for its role in producing fine chemicals and active pharmaceutical ingredients (APIs).
Methyl 4-chloro-2-methoxybenzoate structure
78955-90-5 structure
Product Name:Methyl 4-chloro-2-methoxybenzoate
CAS No:78955-90-5
MF:C9H9ClO3
MW:200.618962049484
MDL:MFCD09800922
CID:581034
PubChem ID:327084
Update Time:2025-06-17

Methyl 4-chloro-2-methoxybenzoate Chemical and Physical Properties

Names and Identifiers

    • Methyl 4-chloro-2-methoxybenzoate
    • Benzoic acid,4-chloro-2-methoxy-, methyl ester
    • 4-Chlor-2-methoxy-benzoesaeure-methylester
    • 4-chloro-2-methoxy-benzoicacidmethylester
    • MFCD09800922
    • AC-24331
    • E78386
    • BS-25944
    • DTXSID00316178
    • 78955-90-5
    • 4-chloro-2-methoxybenzoic acid methyl ester
    • METHYL4-CHLORO-2-METHOXYBENZOATE
    • J-514958
    • AKOS005147189
    • NSC-300574
    • Benzoic acid, 4-chloro-2-methoxy-, methyl ester
    • CS-0127627
    • A9887
    • NSC300574
    • SCHEMBL1484183
    • UTEXPQWKBMXWJD-UHFFFAOYSA-N
    • Methyl 2-methoxy-4-chlorobenzoate
    • NSC 300574
    • DB-119438
    • 4-Chloro-2-methoxy-benzoic acid methyl ester
    • MDL： MFCD09800922
    • Inchi： 1S/C9H9ClO3/c1-12-8-5-6(10)3-4-7(8)9(11)13-2/h3-5H,1-2H3
    • InChI Key： UTEXPQWKBMXWJD-UHFFFAOYSA-N
    • SMILES： O=C(C1C(OC)=CC(Cl)=CC=1)OC

Computed Properties

  • Exact Mass: 200.02400
  • Monoisotopic Mass: 200.0240218g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 184
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.4
  • Topological Polar Surface Area: 35.5?2

Experimental Properties

  • PSA: 35.53000
  • LogP: 2.13520

Methyl 4-chloro-2-methoxybenzoate Security Information

  • Hazardous Material Identification： Xi

Methyl 4-chloro-2-methoxybenzoate Customs Data

  • HS CODE：2918990090
  • Customs Data：

    China Customs Code:

    2918990090

    Overview:

    2918990090. Other additional oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Methyl 4-chloro-2-methoxybenzoate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM155256-25g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5 95%
25g
 $542 2021-06-17
Alichem
A013027858-250mg
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5 97%
250mg
 $504.00 2023-09-01
Alichem
A013027858-500mg
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5 97%
500mg
 $847.60 2023-09-01
Alichem
A013027858-1g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5 97%
1g
 $1504.90 2023-09-01
Chemenu
CM155256-25g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5 95%
25g
 $264 2022-12-31
Apollo Scientific
OR11925-1g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5
1g
 ￡104.00 2023-08-31
Apollo Scientific
OR11925-5g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5
5g
 ￡170.00 2023-08-31
Apollo Scientific
OR11925-25g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5
25g
 ￡536.00 2023-08-31
abcr
AB237369-1 g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5
1g
 €105.20 2022-06-11
abcr
AB237369-5 g
Methyl 4-chloro-2-methoxybenzoate
 78955-90-5
5g
 €200.00 2022-06-11

Methyl 4-chloro-2-methoxybenzoate Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ;  rt; 18 h, 75 °C
Reference
Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors
Capkova, Katerina; Yoneda, Yoshiyuki; Dickerson, Tobin J.; Janda, Kim D., Bioorganic & Medicinal Chemistry Letters, 2007, 17(23), 6463-6466

Production Method 2

Reaction Conditions
1.1 Catalysts: Sulfuric acid ;  overnight, 80 °C
Reference
N-Arylsulfonyl Indolines as Retinoic Acid Receptor-Related Orphan Receptor γ (RORγ) Agonists
Doebelin, Christelle; Patouret, Remi; Garcia-Ordonez, Ruben D.; Chang, Mi Ra; Dharmarajan, Venkatasubramanian; et al, ChemMedChem, 2016, 11(23), 2607-2620

Production Method 3

Reaction Conditions
1.1 Solvents: Ethanol ,  Water
Reference
4,4'-Dichlorosalicil
Kuhn, Richard; Hensel, Hans R., Chemische Berichte, 1951, 84, 557-62

Production Method 4

Reaction Conditions
1.1 Reagents: Potassium hydroxide Solvents: Methanol ;  1 h, rt
1.2 Solvents: Tetrahydrofuran ;  2 d, rt
1.3 Reagents: Diethylamine ;  3 h, rt
Reference
Modulation on C- and N-Terminal Moieties of a Series of Potent and Selective Linear Tachykinin NK2 Receptor Antagonists
Gensini, Martina; Altamura, Maria; Dimoulas, Tula; Fedi, Valentina; Giannotti, Danilo; et al, ChemMedChem, 2010, 5(1), 65-78

Production Method 5

Reaction Conditions
1.1 Reagents: Sulfuric acid Solvents: Methanol
Reference
Heterocyclic tertiary alcohol derivatives (fungicides and plant growth regulators)
, United Kingdom, , ,

Methyl 4-chloro-2-methoxybenzoate Raw materials

Methyl 4-chloro-2-methoxybenzoate Preparation Products

Methyl 4-chloro-2-methoxybenzoate Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:78955-90-5)Methyl 4-chloro-2-methoxybenzoate
Order Number:A9887
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 17:46
Price ($):377.0

Methyl 4-chloro-2-methoxybenzoate Related Literature

Related Categories

78955-90-5 (Methyl 4-chloro-2-methoxybenzoate) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:78955-90-5)Methyl 4-chloro-2-methoxybenzoate
A9887
Purity:99%
Quantity:25g
Price ($):377.0
Email