Cas no 78686-78-9 (Methyl 6-chloro-5-fluoropyridine-3-carboxylate)
Methyl 6-chloro-5-fluoropyridine-3-carboxylate is a fluorinated pyridine derivative commonly used as a versatile intermediate in pharmaceutical and agrochemical synthesis. Its key structural features—the chloro and fluoro substituents—enhance reactivity and selectivity in cross-coupling reactions, making it valuable for constructing complex heterocyclic frameworks. The ester group provides a handle for further functionalization, such as hydrolysis or amidation. This compound exhibits high purity and stability under standard storage conditions, ensuring reliable performance in synthetic applications. Its utility in medicinal chemistry is underscored by its role in the development of bioactive molecules, particularly those targeting CNS and antimicrobial agents.
78686-78-9 structure
Product Name:Methyl 6-chloro-5-fluoropyridine-3-carboxylate
CAS No:78686-78-9
MF:C7H5ClFNO2
MW:189.571504354477
MDL:MFCD14698136
CID:1793813
PubChem ID:12677297
Update Time:2025-10-29
Methyl 6-chloro-5-fluoropyridine-3-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- methyl 6-chloro-5-fluoropyridine-3-carboxylate
- MolPort-008-146-155
- methyl 6-chloro-5-fluoronicotinate
- KB-87225
- 2-Chloro-3-fluoro-5-(methoxycarbonyl)pyridine
- C-2489
- Methyl 2-chloro-3-fluoropyridine-5-carboxylate
- METHYL 2-CHLORO-3-FLUORO-5-PYRIDINECARBOXYLATE
- 3-PYRIDINECARBOXYLIC ACID,6-CHLORO-5-FLUORO-,METHYL ESTER
- Methyl 6-chloro-5-fluoro-pyridine-3-carboxylate
- 6-chloro-5-fluoropyridine-3-carboxylic acid methyl ester
- DTXSID10506563
- CS-0181862
- methyl6-chloro-5-fluoronicotinate
- EN300-7412497
- 78686-78-9
- KDMTVIVGDHCOAH-UHFFFAOYSA-N
- PS-6731
- AKOS016015633
- MFCD14698136
- Z1255459532
- SB52956
- DB-109476
- SCHEMBL990912
- Methyl 6-chloro-5-fluoropyridine-3-carboxylate
-
- MDL： MFCD14698136
- Inchi： 1S/C7H5ClFNO2/c1-12-7(11)4-2-5(9)6(8)10-3-4/h2-3H,1H3
- InChI Key： KDMTVIVGDHCOAH-UHFFFAOYSA-N
- SMILES： ClC1=C(C=C(C(=O)OC)C=N1)F
Computed Properties
- Exact Mass: 188.9992843g/mol
- Monoisotopic Mass: 188.9992843g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 179
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.8
- Topological Polar Surface Area: 39.2?2
Methyl 6-chloro-5-fluoropyridine-3-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C13172-5g |
Methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 5g |
15592CNY | 2021-05-08 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C13172-1g |
Methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 1g |
4032CNY | 2021-05-08 | ||
| TRC | B498730-10mg |
methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 10mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B498730-50mg |
methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 50mg |
$ 95.00 | 2022-06-07 | ||
| TRC | B498730-100mg |
methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 100mg |
$ 135.00 | 2022-06-07 | ||
| Chemenu | CM243884-1g |
Methyl 6-chloro-5-fluoronicotinate |
78686-78-9 | 95% | 1g |
$542 | 2021-08-04 | |
| Chemenu | CM243884-5g |
Methyl 6-chloro-5-fluoronicotinate |
78686-78-9 | 95% | 5g |
$1627 | 2021-08-04 | |
| Frontier Specialty Chemicals | C13172-1 g |
Methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 1g |
$ 189.00 | 2022-11-04 | ||
| Frontier Specialty Chemicals | C13172-5 g |
Methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 5g |
$ 788.00 | 2022-11-04 | ||
| Matrix Scientific | 188025-1g |
Methyl 6-chloro-5-fluoropyridine-3-carboxylate |
78686-78-9 | 1g |
$346.00 | 2023-09-07 |
Methyl 6-chloro-5-fluoropyridine-3-carboxylate Related Literature
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
-
Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
-
Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
-
Chao-Han Cheng,Wen-Zhen Wang,Shie-Ming Peng,I-Chia Chen Phys. Chem. Chem. Phys., 2017,19, 25471-25477
78686-78-9 (Methyl 6-chloro-5-fluoropyridine-3-carboxylate) Related Products
- 38186-88-8(2-chloro-5-fluoropyridine-3-carboxylic acid)
- 82671-06-5(2,6-Dichloro-5-fluoronicotinic acid)
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- 950691-52-8(6-Chloro-5-fluoropyridine-3-carbaldehyde)
- 628691-95-2(methyl 2-chloro-3-fluoropyridine-4-carboxylate)
- 82671-03-2(Ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate)
- 38186-86-6(6-chloro-5-fluoropyridine-3-carboxylic acid)
- 847729-27-5(methyl 2-chloro-5-fluoropyridine-3-carboxylate)
- 139911-30-1(Ethyl 2-chloro-5-fluoronicotinate)
- 189281-66-1(Methyl 2,6-dichloro-5-fluoronicotinate)
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